Urology Times Podcasts9 Syys 2025

Pearls & Perspectives: Prostate MRI and Focal Therapy, with Dan Sperling, MD, DABR

In this episode of Pearls & Perspectives, Amy Pearlman, MD, speaks with Dan Sperling, MD, DABR, a board-certified radiologist and medical director of the Sperling Prostate Center (Florida, New York) and the Sperling Diagnostic Group (Florida). The discussion focuses on advances in prostate MRI, targeted biopsy, and focal therapies for prostate cancer.

Sperling shares how his career evolved from traditional diagnostic imaging into prostate MRI after collaborating with large urology groups frustrated by the limitations of standard transrectal ultrasound-guided prostate biopsy. Early exposure to European innovators in multi-parametric MRI (mpMRI) and in-bore biopsy fueled his adoption of advanced imaging and eventually focal therapies. Although initially met with skepticism, mpMRI is now a central component of prostate cancer care, with MRI-ultrasound fusion biopsies widely adopted as a cost-effective and accurate option.

The conversation highlights the infrastructure required for in-bore MRI biopsies, the evolution of targeted fusion approaches, and how patients often seek Sperling from across the globe for cutting-edge imaging and treatment. His patients, many of whom prioritize quality of life and minimal adverse events, are increasingly exploring focal therapies as alternatives to surgery or radiation.

Sperling explains his use of 3 main focal therapy modalities—focal laser ablation, MRI-guided focused ultrasound, and TULSA (transurethral ultrasound ablation). He outlines factors influencing treatment selection, including tumor location, prostate size, presence of calcifications, and genomic risk. Adverse events are generally mild, with catheter use for a short period post-procedure.

The episode also underscores the role of artificial intelligence (AI) in prostate imaging. Sperling uses multiple AI platforms to refine detection, reduce false positives, aid in targeting, and even help differentiate scar tissue from recurrence after treatment. He sees AI as a rapidly evolving tool that will reshape diagnosis, treatment planning, and surveillance in prostate cancer.

For urologists, Sperling emphasizes the importance of close collaboration with radiologists, adopting MRI-guided diagnostic strategies, and staying informed about focal therapy research. He encourages open-mindedness toward these evolving technologies, which he believes represent an exciting new era in prostate cancer management.

Chapters
1:17 Dr Sperling outlines his background
6:46 Barriers to adoption of MRI-guided biopsy
12:14 Decision making for focal therapy treatments
21:28 Who is the ideal candidate for focal therapy?
24:45 AI's role in Dr Sperling's practice
29:26 Urologist-radiologist collaboration

Tämä jakso on lisätty Podme-palveluun avoimen RSS-syötteen kautta eikä se ole Podmen omaa tuotantoa. Siksi jakso saattaa sisältää mainontaa.

Jaksot(215)

The Expert APProach: Advancing APP Leadership and Expertise in Urology, With Susanne Quallich, PhD, ANP-BC, NP-C

Susanne Quallich, PhD, ANP-BC, NP-C, discusses APP leadership, specialization, professional growth, and expanding the role of APPs in urology.

20 Elo 28min

Pearls & Perspectives: Patient Expectations, Physician Autonomy, and Life Beyond Surgery, With Andrew T. Cohen, MD, FACS

In this episode of Pearls & Perspectives, host Amy Pearlman, MD, and plastic surgeon Andrew T. Cohen, MD, FACS, discuss managing patient expectations and the importance of cultivating balance outside ...

12 Elo 39min

The UroOnc Minute: Navigating BCG Maintenance Therapy in NMIBC, With Mark D. Tyson, II, MD, MPH

In this episode of The UroOnc Minute, Mark D. Tyson, II, MD, MPH, joins host Adam Weiner, MD, to discuss the importance of BCG maintenance therapy in NMIBC and share strategies for navigating treatmen...

12 Elo 13min

Pearls & Perspectives: Wearable Technology and the Future of Sexual Health, With Elliot Justin, MD

Host Amy Pearlman, MD, and guests Larry Lipshultz, MD, and Elliot Justin, MD, explore the potential of wearable technology to advance the diagnosis, monitoring, and optimization of sexual health for b...

12 Elo 15min

Pearls & Perspectives: From Prostate Cancer Diagnosis to Patient Advocacy, with Gabe Canales

In this episode of Pearls & Perspectives, host Amy Pearlman, MD, is joined by male reproductive specialist Larry Lipshultz, MD, and patient advocate Gabe Canales for a candid conversation about prosta...

12 Elo 15min

The UroOnc Minute: Optimizing Patient Follow-Up in Urologic Oncology, With Jason Hafron, MD

In this episode of The UroOnc Minute, host Adam Weiner, MD, is joined by Jason Hafron, MD, to discuss how data-driven pathways and patient follow-up systems can improve quality and outcomes in urologi...

24 Heinä 12min

Pearls & Perspectives: Understanding the Long-Term Health Effects of Military Exposures, With Shane Kronstedt, MD

Host Amy Pearlman, MD, and Larry Lipshultz, MD, speak with Shane Kronstedt, MD, about research on the long-term urologic effects of military exposures and how these findings may help improve care for ...

22 Heinä 5min

First Assist: Early Cystectomy in Non–Muscle Invasive Bladder Cancer, with Matvey Tsivian, MD

In this episode of First Assist: GU Oncology Unpacked, host Taylor Goodstein, MD, is joined by Matvey Tsivian, MD, to discuss how patient selection, staging, and quality-of-life considerations influen...

15 Heinä 49min