Part 43 - Dr. Dale Bredesen and the End of Alzheimer's, How YOU Can Prevent it, and Hope for All Degenerative Diseases
Peak Human - Unbiased Nutrition Info for Optimum Health, Fitness & Living30 Touko 2019

Part 43 - Dr. Dale Bredesen and the End of Alzheimer's, How YOU Can Prevent it, and Hope for All Degenerative Diseases

This is an interview I've been looking forward to for years. Dr. Dale Bredesen is shaking up the medical world by showing that Alzheimer's actually can be prevented, treated, and sometimes even reversed. This is really important to me because my mom is the final stages of Alzherimer's and I, of course, am doing everything I can to prevent myself from falling to the same fate.

I believe the Sapien way of eating and lifestyle is doing just that - setting me up for my best chances at my longest healthspan. You can learn more about this at http://sapien.org/diet

Dr. Bredesen and I agree on all the core principles. He really is describing a Sapien diet with his protocol. We're only at odds with the ratio of plant foods to animal foods.

As I've posted today on social media, I think people are actually more on the side of animal foods than they think. In the context of a whole foods, low carb diet without refined grains, sugar or vegetable oil, more often than not people are getting the majority of their calories from animal foods without necessarily realizing it. Only people eating Standard American Diets or Mediterranean Diets and the like are getting most of their calories from plant foods from all the empty calories coming from grains and other carbohydrates.

Many health figures in this space say things like "a plant heavy diet" or "fill half your plate up with greens" and people take this as being akin to a vegetarian diet. As I showed in my post, a daily intake where about 70% of the plates are filled with plants are actually 92% animal foods by calories.

I actually eat this way a lot. This is carnivore adjacent and is part of the Sapien Framework. You're still getting a ton of flavor, variety, and nutrients from plants (even though they're not as bioavailable), but you're really getting 90% of your calories from animal foods. So make your own decision on the ratio of plant to animal foods, but from what I've found, higher animal foods is more species appropriate for homo sapiens, and is actually what most people avoiding empty calorie, nutrient poor foods are already doing.

As always, I didn't want to press him on this. I don't invite people on my podcast to tell them I don't agree with their opinions. I'd love for this to be debated with a moderator at some point, but as long as it's a 1 on 1 Peak Human podcast I'm letting the guest speak their minds.

Here's a bit of Dr. Bredesen's extensive resume. He received his undergraduate degree from Caltech and his medical degree from Duke. He served as Resident and Chief Resident in Neurology at UCSF, he was the Director of the Easton Center for Alzheimer's Disease Research, he's a Professor in the Department of Molecular and Medical Pharmacology at UCLA School of Medicine, and the Founder of the Buck Institute for Research on Aging.

The Bredesen Laboratory studies basic mechanisms underlying the neurodegenerative process, and the translation of this knowledge into effective therapeutics for Alzheimer's disease and other neurodegenerative conditions, leading to the publication of over 220 research papers. He and his group developed a new approach to the treatment of Alzheimer's disease, and this approach led to the discovery of subtypes of the disease, followed by the first description of reversal of symptoms in patients with MCI and Alzheimer's disease, with the ReCODE protocol, published in 2014, 2016, and 2018. His book, The End of Alzheimer's, is a New York Times Bestseller and has been translated into 29 languages.

I'll largely skip the plugs for today. Everyone listening knows about the Food Lies film on Indiegogo, the Patreon at http://patreon.com/peakhuman and my new grass fed meat company http://NoseToTail.org If you find any value in this podcast or my other content on YouTube or social media channels, please consider supporting me and my projects there. I wish I could really get across how much it means to me. It's honestly the only way any of this is possible. Thanks so much, and I'll most likely end season 3 with this episode and come back in a couple weeks with an amazing season 4. Here's the future legend, Dr. Dale Bredesen.

BUY THE MEAT NosetoTail.org

Preorder Food Lies: http://indiegogo.com/projects/food-lies-post

Support me on Patreon! http://patreon.com/peakhuman

SHOW NOTES

  • Dr. Bredesen has been studying the phenomenon of Alzheimer's Disease (AD) for 3 decades and have published over 200 papers on his research
  • Understanding the fundamental nature of the disease is how we can design an effective treatment
  • His protocol is different because it targets the root cause, not the symptoms like most AD drugs do
  • Humans are extremely complicated and there is no one single therapy that will treat the complexity of AD
  • AD is the result of the brain protecting itself from different insults
  • The protective response in the brain causes the brain to shrink and "retreat" so that there is less for foreign substances (insults) to target
  • Amyloids are antimicrobial, bind to toxins, and change the brain's response to glucose but when they are overproduced and build up that's when problems occur
  • Some of the contributors to AD are: chronic inflammation, insulin resistance, glycation damage, toxin exposure, decrease in nutrients, hormones, trophic factors, poor vascular support
  • He has identified and categorized 6 different types of AD: inflammatory, atrophic, glycotoxic, toxic, vascular, and traumatic
  • Paraffin candles produce toxins that damage the brain
  • Most damaging mycotoxins (produced from mold) are the ones you breathe - test your home for molds
  • Go to www.survivingmold.com to learn how to test your home for mold and if you are concerned about mold exposure to learn about what to personally get tested
  • For overall markers you should get tested, you can order tests directly from Dr. Bredesen's site www.drbredesen.com or go to your doctor and test markers
  • Markers for glycotoxicity: fasted insulin, HbA1c, and fasted glucose
  • Markers for nutrients, hormones, and trophic factors: o Vit. D, pragnenolone, progesterone, estradiol, testosterone, free T3 and free T4 (for thyroid), TSH (thyroid stimulating hormone), and reverse T3 (which is an inhibitor of the effect of your active thyroid hormone)
  • Inflammation markers: HS-CRP, TNF-a, IL6, IL8, IL1-b
  • Don't wait until it's too late to check for these things, because AD is preventable
  • Glycotoxicity and how sugar is toxic
  • Humans are not designed to eat sugar
  • Overconsumption of sugar is linked to hypertension, CVD, diabetes, dementia, arthritic, leaky gut, and more
  • Sugar is this generation's smoking, we will get to a day when we think back to how crazy it was that we were eating this stuff
  • We have biomarkers that will tell you whether AD is creeping up on you, so check early in life because you might not feel sick now, but that doesn't mean it's not on its way
  • All these lifestyle and diet changes that you make to prevent AD, apply to so many other modern illnesses
  • If AD runs in your family, you should be interested in prevention
  • AD should be a rare disease
  • APOE4 is the most common genetic risk factor
  • If you have a single copy of APOE4 the risk is ~30%
  • If you have a double copy of APOE4 the risk becomes greater than 50%
  • For people with APOE4, find out early and get on prevention, and you will have a low chance of getting the disease
  • 21st century medicine is about root cause and prevention
  • There is no mono-therapy for AD
  • Look out for symptoms of early cognitive decline like the lack of ability to learn new things, losing organizational skills, not being able to do simple calculations, not being able to find the right word, getting lost in familiar places
  • Don't shake these off as "senior moments"
  • Basic things everyone can do: optimize insulin sensitivity, follow a low-carb, moderate protein, high (good) fat diet, exercise, get enough sleep, reduce stressors in your life, detox, avoid or fix any gut issues, go into periods of ketosis
  • His diet plan is called "KetoFlex 12/3"
  • "Keto" for going into periods of ketosis
  • "Flex" because it is flexitarian, if you want to be a vegetarian or eat meat you can do either
  • "12" because he wants people fasting for at least 12 hours between dinner and the next day's first meal
  • "3" because he wants people to finish eating at least 3 hours before they go to sleep
  • The Big Four to avoid: grains, simple carbs, dairy, and lectins
  • He has had amazing success with his patients and has been publishing results since 2014
  • He has never had someone at risk come in for prevention and develop even mild cognitive impairment (MCI)
  • People who come in with subjected cognitive impairment (SCI) see improvement
  • People who come in with MCI the majority improve
  • People with full-blown AD, some people improve and some people don't
  • He has had people score zero on cognitive tests that have improved
  • The most important point of all of this is that if you get put on a drug for AD you might get a little bump but you fall back to declining again, his approach targets what is actually causing the decline, the people who get better sustain their improvement
  • Complexity gap between the complexity of the problem (human illness) and the data sets that traditional medical doctors are using to treat them (aka we can't expect a simple mono-therapy to treat a complex condition)
  • Dr. Bredesen's daughter is a brain health coach and you can find her at www.siabrainhealth.com
  • His protocol includes sauna for riding the body of toxins
  • We are swimming in an Alzheimer's soup with the amount of toxins we are exposed to in our modern world
  • Get rid of toxins by sweating (sauna and exercise), high fiber diet, optimizing glutathione levels, filtered water, urination, each one of these gets rid of different things
  • If you have leaky gut, fix that
  • The importance of sleep
  • Current research on macular degeneration
  • His new book coming out "The First Survivors of Alzheimer's Disease" will be about people's first-hand stories of people told they had no hope but used his protocol and got better and have kept themselves better
  • The future of medicine will need to look at how humans were evolutionarily designed to live
  • You are not powerless to AD, you have control over it
  • We can reduce the global burden of dementia, we can fight cognitive decline
  • Find Dr. Dale Bredesen at www.drbredesen.com
  • His Facebook page https://facebook.com/drdalebredesen/

BUY THE MEAT NosetoTail.org

Support me on Patreon! http://patreon.com/peakhuman

Preorder the film here: http://indiegogo.com/projects/food-lies-post

Film site: http://FoodLies.org

YouTube: https://www.youtube.com/c/FoodLies

Sapien Movement: http://SapienMovement.com

Follow along:

http://twitter.com/FoodLiesOrg

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Theme music by https://kylewardmusic.com/

Jaksot(233)

Part 185 - Layne Norton, PhD and The Great Diet Debate

Part 185 - Layne Norton, PhD and The Great Diet Debate

Layne completed a BS in Biochemistry and a PhD in Nutritional Sciences, honing his intellectual skills under Dr. Donald Layman, one of the foremost researchers on protein metabolism and fat loss in the world. He has also enjoyed success in bodybuilding, winning a natural pro card in 2006. He is the founder of BioLayne. He created the company to provide ethical, science-based coaching that synthesized real world experience with evidence based protocols. In his coaching career he has turned over 70 people pro and reshaped the way that countless people think about nutrition. https://biolayne.com GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org SHOW NOTES: (9:51) There is no "one-size-fits-all" prescription in the fitness and nutrition space. (19:50) There is no such thing as "good" and "bad" foods. (24:15) Nuance is king in the fitness and nutrition space. (31:36) Don't sweat the carb/fat debate. (49:01) Layne doesn't claim to be an arbiter of truth; but, he's all for intellectual honesty. (1:03:00) Brian and Layne debate on common points of contention in nutritional science. (1:22:30) It's much easier to live an unhealthy life today compared to just three decades ago. Learn more about the individuals and studies we mentioned in today's episode: Dr. Ted Naiman: https://www.dietdoctor.com/authors/dr-ted-naiman-md "Co-consumption of Vegetables and Fruit, Whole Grains, and Fiber Reduces the Cancer Risk of Red and Processed Meat in a Large Prospective Cohort of Adults from Alberta's Tomorrow Project": https://www.mdpi.com/2072-6643/12/8/2265 Ultra-Processed Diets Cause Excess Calorie Intake and Weight Gain: An Inpatient Randomized Controlled Trial of Ad Libitum Food Intake: https://www.cell.com/cell-metabolism/pdf/S1550-4131(19)30248-7.pdf GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

15 Helmi 20231h 36min

Part 184 - Dr. Scott Sherr on Optimizing Your Mitochondria For Peak Health

Part 184 - Dr. Scott Sherr on Optimizing Your Mitochondria For Peak Health

Dr. Scott Scherr is an Internal Medicine MD. CoFounder of OneBase health, COO of Troscriptions, and HOMe. A specialist in HBOT, Dr. Scott is interested in all things health/performance optimization. IG: https://www.instagram.com/drscottsherr/?hl=en Websites: https://linktr.ee/drscottsherr   GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org   SHOW NOTES: Coming soon       GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org   Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

8 Helmi 20231h 29min

Part 183 - Dr. Molly Maloof on True Heath in the Modern World

Part 183 - Dr. Molly Maloof on True Heath in the Modern World

Dr. Molly Maloof is a Healthspan Doctor, determined to maximize our potential with health optimization, biohacking, and personalized wellness. Founder of multiple wellness-focused organizations, and having served as medical advisor for a multitude of brands, she's on a mission to help us all live our best lives through education and health awareness. She is the author of Spark Factor: The Secret to Supercharging Energy, Becoming Resilient, and Feeling Better Than Ever which is now open for pre-order. Dr. Molly's Website: https://drmolly.co/ BUY THE MEAT NosetoTail.org Preorder the film here: http://indiegogo.com/projects/food-lies-post SHOW NOTES 1:55 - Dr. Molly's background 4:25 - Healthspan and the role of Mitochondria 13:30 - Blood sugar and different carb types 17:30 - The myth of the Calories in/Calories out theory 20:37 - The truth of healthcare and predictions for the industry 27:42 - Trying to stay healthy in a new environment 30:40 - How is technology changing health? 34:00 - The role of social connection in living a healthy life. 37:35 - How to make friends and improve your network 42:20 - Dr. Molly's health journey and becoming a doctor 48:58 - How trauma affects our health and navigating sexual and relationship experiences 58:20 - Women's biohacking BUY THE MEAT NosetoTail.org Preorder the film here: http://indiegogo.com/projects/food-lies-post Film site: http://FoodLies.org YouTube: https://www.youtube.com/c/FoodLies Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

1 Helmi 20231h 16min

Part 182- Natalie Kovarik and Tara Vander Dussen - Is Walmart Beef & Milk Healthy?

Part 182- Natalie Kovarik and Tara Vander Dussen - Is Walmart Beef & Milk Healthy?

Natalie Kovarik Natalie is a Ranch wife, mother, and social entrepreneur. She's grown from an instagram following to include her own podcast, clothing line, an online course, and she now hosts marketing retreats for women in rural lifestyles. Natalie's website: https://nataliekovarik.com Tara Vander Dussen Tara is a 5th generation dairy farmer, environmental scientist, farm wife, and mother to 2 girls. She serves as president of United Dairy Women, a charity dedicated to providing dairy to families in New Mexico. A passionate advocate for all things dairy farming. She's proudly known as the New Mexico Milkmaid when sharing online. Her mission is to share the truth about dairy farming and weed out the misconceptions about farming and farm life. Tara's Website: https://taravanderdussen.com/ Together with Tara they host the DiscoverAg podcast and help women with agriculture marketing with their Ecourses and Facebook community ElevateAg. GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org SHOW NOTES [4:28] - Nuances of the ranching solution. [8:00] - Types of ranching operations [11:15] - Breakdown of farm sizes and stats in the US [13:00] - Common misconception that cows spend their lives in cages [15:10] - Cattle are naturally herd animals, it gives off a misconception that they're always packed super close together when on pastures [17:53] - The majority of people have been fed the propaganda that meat is the enemy [21:00] - Are there bad players/practices in the industry? [28:40] There's a lot of arguments about how we get our food, but ultimately we still need some amount of efficiency for such large populations [34:45] How has the quality of milk/meat changed? Can cows actually eat corn and non-traditional diets. [39:52] Is marbled meat bad? [48:39] What are some of the differences in nutrition with lab grown meat? [53:10] - Is climate change a human cause? What's the truth? [59:29] Meat based diets are making a comeback and gaining traction over veganism. GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

26 Tammi 20231h 13min

Part 181 - Elliot Overton on 2 Huge Nutrition Aspects That Could Change Your Health

Part 181 - Elliot Overton on 2 Huge Nutrition Aspects That Could Change Your Health

After developing some minor health issues of his own after an extended back-packing trip through Asia,  Elliot decided to take responsibility and began researching ways by which he could find resolution without the use of pharmaceutical medications. Elliot soon discovered that the solution to his problems was rooted in nutrition and basic lifestyle principles.  Elliot's  experience, and the experience of those close to him, demonstrated the power of nutritional intervention. Elliots success in improving his own health journey inspired him to study nutrition at a professional standard so that he could go on to help others along the way. Elliot trained as a nutritional therapist at the College of Naturopathic Medicine in the UK, and later gained a qualification in Functional Medicine. https://www.eonutrition.co.uk/   BUY THE MEAT NosetoTail.org Preorder the film here: http://indiegogo.com/projects/food-lies-post     SHOW NOTES 01:20  How Elliot got interested in thiamine 06:50  Are you getting enough Thiamine When animals were given large doses of thiamine before being exposed to head trauma, it was shown to mitigate many of the negative ramifications of the head injury, and allow for normal functions to be carried out at a greater rate than the control group. https://www.sciencedirect.com/science/article/pii/S0005272818301208  Very high doses of B1 have been found to completely abolish symptoms of Alzheimer's disease. https://www.hormonesmatter.com/new-developments-in-high-dose-thiamine-the-legacy-of-antonio-costantini/  Large doses of thiamine have also demonstrated two almost completely abolished symptoms of fibromyalgia seemingly overnight. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669831/#:~:text=Some%20observations%20indicate%20that%20the,mitochondria%20or%20to%20enzymatic%20abnormalities.  21:20  Why don't more people know about thiamine? 38:00  Oxalates and thiamine  Elliot credits much of his knowledge of oxalates to Susan Owens, who's website can be found here: http://lowoxalate.info/  54:40  Brian's story with oxalates 59:10  signs and symptoms of oxalates issues 1:10:00 Why Elliot chose thiamine and oxalates 1:17:00  Thiamine and the diet 1:30:00  How to find Elliot  Instagram- https://instagram.com/eonutrition?igshid=YmMyMTA2M2Y= Twitter- Elliot Overton (@EO_Nutrition) / Twitter https://twitter.com/eo_nutrition?lang=en  YouTube - https://youtube.com/@EONutrition Website- https://www.eonutrition.co.uk/     BUY THE MEAT NosetoTail.org Preorder the film here: http://indiegogo.com/projects/food-lies-post   Film site: http://FoodLies.org YouTube: https://www.youtube.com/c/FoodLies   Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

18 Tammi 20231h 41min

Part 180 - Mike Mutzel Gives a Masterclass on Reading Labs & Bloodwork

Part 180 - Mike Mutzel Gives a Masterclass on Reading Labs & Bloodwork

Mike earned his B.S. in Biology from Western Washington University in 2006 and completed his M.S. in Clinical Nutrition from the University of Bridgeport in 2015 and is a graduate of the Institute for Functional Medicine's (IFM) Applying Functional Medicine in Clinical Practice (AFMCP). https://highintensityhealth.com/about/ BUY THE MEAT NosetoTail.org Preorder the film here: http://indiegogo.com/projects/food-lies-post SHOW NOTES: 00:00- Head over to https://nosetotail.org/ for our nose to tail products Go to http://drinklmnt.com/peakhuman for a free gift from LMNT electrolytes. Join the sapien newsletter https://www.sapien.org/ 04:00- It will be much better to watch the video presentation on the Food Lies YouTube 06:24- The importance of exercise 12:40- Carb cycling and timing 15:20- Effects of blood viscosity 26:38- LDL cholesterol 35:00- How to assess the liver 39:13- Benefits of cholesterol 40:56- Triglycerides and a case study 47:10- Omega 3 and 6 49:30- Vitamin D 55:30- Mike's approach to looking at labs. Case studies 1:04:20- Post menopause 1:06:23- DHEA 1:09:05- Common male bloodwork For full show notes with links to all the studies join the Patreon BUY THE MEAT NosetoTail.org Preorder the film here: http://indiegogo.com/projects/food-lies-post Film site: http://FoodLies.org YouTube: https://www.youtube.com/c/FoodLies Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

29 Joulu 20221h 13min

Part 179 - Dr. Aseem Malhotra on Was It Safe & Effective?

Part 179 - Dr. Aseem Malhotra on Was It Safe & Effective?

Dr Aseem Malhotra is an NHS Trained Consultant Cardiologist, and visiting Professor of Evidence Based Medicine, Bahiana School of Medicine and Public Health, Salvador, Brazil. He is a world renowned expert in the prevention, diagnosis and management of heart disease. He is honorary council member to the Metabolic Psychiatry Clinic at Stanford University school of medicine California, and is Cardiology MSc examiner at the University of Hertfordshire, UK. He is a founding member of Action on Sugar and was the lead campaigner highlighting the harm caused by excess sugar consumption in the United Kingdom, particularly its role in type 2 diabetes and obesity. https://doctoraseem.com/biography/ Get the free gift from LMNT DrinkLMNT.com/PeakHuman GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org SHOW NOTES: 00:30- Introduction 04:03- How Dr. Aseem's views have changed 06:15- Transition to Rumble 08:18- A framework for the rest of the discussion 13:28- the evidence-based medicine triad 15:35- how to survive the medical miss information mess 18:30- The corruption of medicine from pharmaceutical companies 19:20- Blatant misconduct from the pharmacy industries 21:15- What about the life-saving drugs? 29:00- Statistical literacy 32:25- The effects of fear and stress 34:20- The real impact of the vaccine 49:00- Dr. Aseem's consensus on the data 1:00:00- The harms of the vaccine 1:08:00- Getting to the root of the problem? 1:28:30- Where to find the best products on the market For full show notes join the Peak Human Patreon http://patreon.com/peakhuman GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

16 Joulu 20221h 34min

Part 178 - Dr. Suneel Dhand on Big Pharma Bribing Your Doctor & Worldwide Corruption

Part 178 - Dr. Suneel Dhand on Big Pharma Bribing Your Doctor & Worldwide Corruption

Dr. Suneel Dhand is an internist in Hyannis, Massachusetts and is affiliated with multiple hospitals in the area, including Salem Hospital and Beth Israel Deaconess Medical Center. He received his medical degree from The University of Wales College of Medicine and has been in practice between 11-20 years. https://suneeldhand.com/ BUY THE MEAT NosetoTail.org FREE SAPIEN LIFESTYLE GUIDE Sapien.org SHOW NOTES: 00:18- Introduction to Dr. Dhand 05:00- Dr. Dhand transition out of the typical healthcare system 08:00- Your doctor wants you to be sick 10:00- How big pharma is bribing your doctor 11:30- Dr. Dhand approach to treating his patients 15:45- Using food as medicine 21:35- Why eating meat could actually be dangerous 23:15- Dr. Dhand's optimistic view of our health future 25:30- The corruption of medicine 30:40- The real Anthony Fauci 34:20- The intertwined agenda of big pharma, big tech, and mainstream media 41:30- Big pharma's flawed studies 50:50- Medical dictatorship and mass psychosis 58:45 - The effects of mainstream media 1:04:10- The fallacy of the "greater good" 1:18:55- Where to find Dr. Dhand BUY THE MEAT NosetoTail.org Support me on Patreon! http://patreon.com/peakhuman Preorder the film here: http://indiegogo.com/projects/food-lies-post Film site: http://FoodLies.org YouTube: https://www.youtube.com/c/FoodLies Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

7 Joulu 20221h 24min

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