Symposium | Understanding the differences between FLT3-ITD and -TKD mutations in AML: Q&A
AML Hub12 Feb

Symposium | Understanding the differences between FLT3-ITD and -TKD mutations in AML: Q&A

The AML Hub held a virtual symposium on November 19, 2025, titled Understanding the differences between FLT3-ITD and -TKD mutations in AML: Implications for clinical practice. The symposium ended with a panel Q&A discussion with live audience participation.


The panelists, Gail J. Roboz, Jorge Sierra, and Jorge Cortes, shared their perspectives on treatment decisions for patients with FLT3-mutated acute myeloid leukemia, including choice of FLT3 inhibitor, how FLT3-mutated measurable residual disease (MRD) might guide transplant decisions, as well as the importance of monitoring FLT3-mutated MRD with the appropriate assay.


This educational resource is independently supported by Daiichi Sankyo. All content was developed by SES in collaboration with an expert steering committee. Funders were allowed no influence on the content of this resource.

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Episoder(40)

Menin inhibitors in AML: Where are we now, and where are we going?

Menin inhibitors in AML: Where are we now, and where are we going?

During a meeting of the AML Hub Steering Committee, held on February 19, 2026, Jorge Cortes chaired a discussion on the topic, Menin inhibitors in AML: Where are we now, and where are we going? The di...

22 Mai 30min

Managing side effects of menin inhibitors in clinical practice

Managing side effects of menin inhibitors in clinical practice

The AML Hub was pleased to speak with Gail Roboz, Weill Cornell Medicine, New York, US. We asked, What side effects are typically observed with menin inhibitor-based regimens, and how do you approach ...

21 Mai 7min

 Mechanisms and rationale for menin inhibitor combination strategies in AML

Mechanisms and rationale for menin inhibitor combination strategies in AML

The AML Hub was pleased to speak with Eunice Wang from Roswell Park Comprehensive Cancer Center, Buffalo, US. We asked, What are the mechanisms and rationale for menin inhibitor combination strategies...

20 Mai 4min

Treatment decisions in AML: Personalizing care with FLT3 inhibitor therapy

Treatment decisions in AML: Personalizing care with FLT3 inhibitor therapy

During a meeting of the AML Hub Steering Committee, held on February 19, 2026, Jorge Sierra chaired a discussion on the topic, Treatment decisions in acute myeloid leukemia (AML): Personalizing care w...

19 Mai 32min

What key insights are emerging from ongoing trials of menin inhibitor combination strategies in AML?

What key insights are emerging from ongoing trials of menin inhibitor combination strategies in AML?

The AML Hub was pleased to speak with Joshua Zeidner, University of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill, US. We asked, What key insights are emerging from ongoing trials...

15 Mai 5min

Symposium | Implications for clinical practice: Managing AML with FLT3-ITD and -TKD mutations

Symposium | Implications for clinical practice: Managing AML with FLT3-ITD and -TKD mutations

The AML Hub held a virtual symposium on November 19, 2025, titled Understanding the differences between FLT3-ITD and -TKD mutations in AML: Implications for clinical practice. Here, we share a present...

11 Feb 14min

Symposium | Comparing treatment options for patients with FLT3-ITD and -TKD mutations

Symposium | Comparing treatment options for patients with FLT3-ITD and -TKD mutations

The AML Hub held a webinar on November 19, 2025, titled, Understanding the differences between FLT3-ITD and -TKD mutations in AML: Implications for clinical practice. Here, we share a presentation fro...

19 Jan 20min

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