This Nobel Prize Discovery Reverses Aging In 72 Hours : 1432

This Nobel Prize Discovery Reverses Aging In 72 Hours : 1432

Is aging an inevitable decline, or just a "repair backlog" your body hasn't cleared yet?. In this episode, Dave breaks down the 2016 Nobel Prize-winning science of autophagy—the body's internal recycling system discovered by Dr. Yoshinori Ohsumi.


Most people are stuck in a state of "biological debt," where cellular junk piles up like trash in a factory, leading to brain fog, fatigue, and chronic inflammation. Standard 16-hour fasts aren't enough to reach the deep-cleaning phase. You will learn the exact 3-day protocol to trigger a "Deep Reset," where ketones peak, inflammation falls, and stem cells wake up to rebuild your immune system from scratch.


Join my FREE Fasting Challenge: https://daveasprey.com/fast-this-way-challenge/


Timestamps:

00:00 - The Anti-Aging Switch

01:30 - Chronological vs. Biological Age

02:32 - How Aging Works at the Cellular Level

04:58 - 43 Ways to Upgrade Your Mitochondria

07:37 - What Is Autophagy

09:17 - The Stages of Fasting

10:46 - What Happens During a 3-Day Fast

13:04 - How to Fast Correctly

14:42 - Breaking the Fast

15:58 - The Power of Subtraction


Thank you to our sponsors!

-KILLSwitch | If you’re ready for the best sleep of your life, order now at https://www.switchsupplements.com/ and use code DAVE for 20% off

-Join My Low-Oxalate 30-Day Challenge: https://daveasprey.com/2026-low-ox-reset/


Connect with Dave Asprey!


Website: https://daveasprey.com

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Facebook: https://www.facebook.com/Daveaspreyofficial/

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YouTube: https://www.youtube.com/c/daveaspreybpr


The Human Upgrade Podcast: https://www.instagram.com/TheHumanUpgradePodcast/ https://m.facebook.com/Thehumanupgrade/


Danger Coffee: https://dangercoffee.com/DAVE15

Dave Asprey’s BEYOND Conference: https://beyondconference.com/

Dave Asprey’s New Book - Heavily Meditated: https://daveasprey.com/heavily-meditated/

Dave's favorite supplements: https://www.shopsuppgradelabs.com/discount/DAVE15

Upgrade Labs: https://upgradelabs.com

40 Years of Zen: https://40yearsofzen.com

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Episoder(1488)

Your Telomeres Are a Lie, Bats Beat Aging, Sleep Meds Ruin Mornings, CO's Silent Kill, and more... : 1431

Your Telomeres Are a Lie, Bats Beat Aging, Sleep Meds Ruin Mornings, CO's Silent Kill, and more... : 1431

This week’s stories: Smartphone App Catches What Sleep Trackers Miss A 2026 trial found that suvorexant, a popular prescription sleep drug, improves sleep quality scores — but worsens morning alertnes...

13 Mar 12min

Your Penis Is a Longevity Organ (Here's How to Hack It) : 1430

Your Penis Is a Longevity Organ (Here's How to Hack It) : 1430

Testosterone levels in 40-year-old men are 30 percent lower than their fathers, and most doctors still have no idea what to do about it. -Watch this episode on YouTube for the full video experience: h...

12 Mar 1h 3min

AI Expert Says: Humans Are Just Mystical Meat Robots : 1429

AI Expert Says: Humans Are Just Mystical Meat Robots : 1429

What if understanding how AI thinks could reveal uncomfortable truths about how your own brain works, and give you powerful tools to make smarter decisions, resist manipulation, and upgrade your cogni...

10 Mar 57min

How I Finally FIXED My Terrible Sleep After 18 Years  : 1428

How I Finally FIXED My Terrible Sleep After 18 Years : 1428

Block toxic light with these glasses: https://truedark.com/discount/DAVETUBEThink 8 hours of sleep is enough? Think again. I used to think I had a sleep issue—turns out, it was a light issue. In this ...

8 Mar 9min

WW3 Doomscrolling, 5 Minute Sleep Hack, Diet Wars, Dopamine Supplements : 1427

WW3 Doomscrolling, 5 Minute Sleep Hack, Diet Wars, Dopamine Supplements : 1427

This week’s stories: Healthy Diets That Offset "Bad Genes" A major UK Biobank study of over 100,000 people found that following any one of five healthy dietary patterns was associated with up to 3 ext...

6 Mar 11min

Your Brain Is 0.5% Plastic (Here’s How to Flush It) : 1426

Your Brain Is 0.5% Plastic (Here’s How to Flush It) : 1426

Microplastics are invading your brain, blood, hormones, and fat tissue, and most people have no idea how deep the damage goes. In this episode, Host Dave Asprey and microplastics expert Josephine Musc...

5 Mar 56min

Why Are Hackers Microdosing “Sex Drugs” Now?  : 1425

Why Are Hackers Microdosing “Sex Drugs” Now? : 1425

Most doctors treat the average patient. But you are not average, and this episode gives you the precision medicine blueprint to treat yourself like the individual you are, using multi-omic testing, bi...

3 Mar 53min

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