Ep 47 | Is Estrogen Safe After a Blood Clot? The Answer Is Annoyingly Complicated

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Blood clots and hormone therapy: two things that can make perimenopause feel even more delightfully complicated.

In this episode of OvaryActive, Dr. Rebecca Dunsmoor-Su and Dr. Amy Voedisch dig into the risk of blood clots with menopausal hormone therapy, and why the internet's favorite phrase, "It's totally safe," deserves a few very large asterisks.

Rebecca and Amy take a data-driven look at what we actually know about oral versus transdermal estrogen, including findings from the Million Women Study.

They also explain what "provoked" blood clots really mean, when prior clots may make estrogen especially risky, why a hematologist might need to join the group chat, and how shared decision-making should work when the research doesn't give a clean yes-or-no answer.

Listeners will come away understanding why hormone therapy recommendations need to be individualized, what questions to ask their clinician, and why "we don't have enough data yet" is sometimes the most medically accurate answer available.

What you'll hear in this episode:

[0:43] Clot risk controversy

[1:54] Not birth control estrogen

[3:15] Million Women Study

[10:31] Let's talk about our high risk ladies

[12:03] Provoked clots debate

[18:54] Prior clot evidence

[25:05] Clinical counseling approach

[30:25] Shared decision making

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Estrogen, Interrupted by Dr. Rebecca Dunsmoor-Su & Dr. Amy Voedisch

Support the show: patreon.com/cw/OvaryActive

Meet the Docs:

More information about Dr. Rebecca Dunsmoor-Su:

Gennev: www.gennev.com/clinician/dr-rebecca-dunsmoor-su

LinkedIn @rebecca-dunsmoor-su

More information about Dr. Amy Voedisch:

Stanford Medical Clinic: stanfordhealthcare.org/doctors/v/amy-voedisch.html

This episode was produced by Audiotocracy Podcast Production.