Spatial Organization of the Human Genome (Wendy Bickmore)

Spatial Organization of the Human Genome (Wendy Bickmore)

In recent years it has become more and more evident, that genome folding and chromatin packaging into the nucleus plays a pivotal role in the regulation of gene expression. In this Episode of our Podcast our host Dr. Stefan Dillinger spoke with Professor Wendy Bickmore about her work on the spatial organization of the human genome. Prof. Bickmore and her team mainly use visual methods like fluorescence in situ hybridisation (FISH) to study the organization of chromosomes in human and murine cells and how they contribute to transcriptional regulation and how this organization changes during ageing, development or disease.

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Episoder(167)

Evolutionary Forces Shaping Mammalian Gene Regulation (Emily Wong)

Evolutionary Forces Shaping Mammalian Gene Regulation (Emily Wong)

In this episode of the Epigenetics Podcast, we talked with Emily Wong from the University of New South Wales in Sydney about her work on how evolution shapes mammalian genes. As the head of the Regula...

18 Sep 202542min

Chromatin Evolution (Arnau Sebé-Pedrós)

Chromatin Evolution (Arnau Sebé-Pedrós)

In this episode of the Epigenetics Podcast, we talked with Arnau Sebé-Pedrós from the Center for Genomic Regulation in Barcelona about his work on chromatin evolution. The Interview starts by examinin...

4 Sep 202546min

Epigenetic Mechanisms in Breast Cancer (Luca Magnani)

Epigenetic Mechanisms in Breast Cancer (Luca Magnani)

In this episode of the Epigenetics Podcast, we talked with Luca Magnani from Institute of Cancer Research and UNIMI in Milan about his work on epigenetic mechanisms of drug resistance and cancer cell ...

21 Aug 202537min

How BRD4 and H2BE Influence Neuronal Activity (Erica Korb)

How BRD4 and H2BE Influence Neuronal Activity (Erica Korb)

In this episode of the Epigenetics Podcast, we talked with Erica Korb from the University of Pennsylvania about her work on BRD4 and the histone variant H2BE, which influences synaptic genes and neuro...

7 Aug 202537min

Mapping the Epigenome: From Arabidopsis to the Human Brain (Joseph Ecker)

Mapping the Epigenome: From Arabidopsis to the Human Brain (Joseph Ecker)

In this episode of the Epigenetics Podcast, we talked with Dr. Joseph Ecker from the Salk Institute about his work on high-resolution genome-wide mapping technologies, specifically how the regulation ...

24 Jul 202544min

The Human Cell Atlas (Sarah Teichmann)

The Human Cell Atlas (Sarah Teichmann)

In this episode of the Epigenetics Podcast, we talked with Sarah Teichmann from the University of Cambridge about the Human Cell Atlas. In the Interview we explore Sarah Teichmann's impressive career ...

10 Jul 202546min

The Discovery of Genomic Imprinting (Azim Surani)

The Discovery of Genomic Imprinting (Azim Surani)

In this episode, Professor Asim Surani, shares how his extensive research has significantly advanced the understanding of how the mammalian germline is specified, the mechanisms governing epigenetic r...

19 Jun 202556min

Exploring DNA Methylation and TET Enzymes in Early Development (Petra Hajkova)

Exploring DNA Methylation and TET Enzymes in Early Development (Petra Hajkova)

In this episode of the Epigenetics Podcast, we talked with Petra Hajkova from the MRC Laboratory of Medical Sciences about her work on epigenetics research on mammalian development, highlighting DNA m...

5 Jun 202539min

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