Spatial Organization of the Human Genome (Wendy Bickmore)

Spatial Organization of the Human Genome (Wendy Bickmore)

In recent years it has become more and more evident, that genome folding and chromatin packaging into the nucleus plays a pivotal role in the regulation of gene expression. In this Episode of our Podcast our host Dr. Stefan Dillinger spoke with Professor Wendy Bickmore about her work on the spatial organization of the human genome. Prof. Bickmore and her team mainly use visual methods like fluorescence in situ hybridisation (FISH) to study the organization of chromosomes in human and murine cells and how they contribute to transcriptional regulation and how this organization changes during ageing, development or disease.

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Episoder(169)

The Discovery of Genomic Imprinting (Azim Surani)

The Discovery of Genomic Imprinting (Azim Surani)

In this episode, Professor Asim Surani, shares how his extensive research has significantly advanced the understanding of how the mammalian germline is specified, the mechanisms governing epigenetic r...

19 Jun 202556min

Exploring DNA Methylation and TET Enzymes in Early Development (Petra Hajkova)

Exploring DNA Methylation and TET Enzymes in Early Development (Petra Hajkova)

In this episode of the Epigenetics Podcast, we talked with Petra Hajkova from the MRC Laboratory of Medical Sciences about her work on epigenetics research on mammalian development, highlighting DNA m...

5 Jun 202539min

Epigenetic Regulation and Small Molecule Innovation in AML: Advances in Translational Leukemia Research (Ani Deshpande)

Epigenetic Regulation and Small Molecule Innovation in AML: Advances in Translational Leukemia Research (Ani Deshpande)

In this episode of the Epigenetics Podcast, we talked with Ani Deshpande from Sanford Burnham Prebys about his work on epigenetic regulation and developing small molecules through high throughput scre...

22 Mai 20251h

Beyond Mom: Rethinking Paternal Influence in Epigenetic Inheritance (Raffaele Teperino)

Beyond Mom: Rethinking Paternal Influence in Epigenetic Inheritance (Raffaele Teperino)

In this episode Dr. Raffaele Teperino shares insights from his ongoing research focused on developmental programming, particularly how paternal health before conception influences not only offspring h...

8 Mai 202559min

Evolutionary Epigenetic Clocks and Epigenetic Inheritance in Plants (Frank Johannes)

Evolutionary Epigenetic Clocks and Epigenetic Inheritance in Plants (Frank Johannes)

In this episode of the Epigenetics Podcast, we talked with Dr. Frank Johannes from the Technical University of Munich in Freising about his work on evolutionary clocks and epigenetic inheritance in pl...

24 Apr 202539min

Neuroepigenetic Mechanisms and Primate Epigenome Evolution (Boyan Bonev)

Neuroepigenetic Mechanisms and Primate Epigenome Evolution (Boyan Bonev)

In this episode of the Epigenetics Podcast, we talked with Boyan Bonev from the HelmholtzZetrum in Munich about his work on neuroepigenetics, focusing on gene regulation, chromatin architecture, and p...

10 Apr 202545min

The Role of H3K4me3 in Embryonic Development (Eva Hörmanseder)

The Role of H3K4me3 in Embryonic Development (Eva Hörmanseder)

In this episode of the Epigenetics Podcast, we talked with Dr. Eva Hörmanseder from the HelmholtzZentrum in Munich about her work on epigenetic mechanisms in cellular memory and gene regulation. In th...

27 Mar 202537min

Using RICC-Seq to Probe Short Range Chromatin Folding (Viviana Risca)

Using RICC-Seq to Probe Short Range Chromatin Folding (Viviana Risca)

In this episode of the Epigenetics Podcast, we talked with Viviana Risca from Rockefeller University about her work on RICC-Seq and how it's used to probe DNA-DNA contacts in intact or fixed cells usi...

13 Mar 202546min

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