We Can Slow Down Aging Right Now – David Sinclair, Ph.D.  : 626

We Can Slow Down Aging Right Now – David Sinclair, Ph.D. : 626

In this episode of Bulletproof Radio,my guest is an Australian biologist best known for his research on lifespan extension and the treatment of diseases for aging.

“I'm a scientist,” says David Sinclair, Ph.D., “and I'm trying to figure this stuff out before time runs out for all of us.”

David is a professor in the department of Genetics at Harvard Medical School and also co-director of Harvard’s Paul F. Glenn Center for the Biology of Aging. He’s the co-creator and co-chief editor of the journal Aging, has co-founded several biotechnology companies, and is an inventor of nearly three dozen patents.

Among the career honors and awards he’s received are his inclusion in Time Magazine’s list of the “100 Most Influential People in the World” in 2014 and “The Healthcare 50: Fifty People Transforming Healthcare in 2018.”

For two decades, his research at The Sinclair Lab has consistently focused on understanding how and why human beings age and how to slow its effects.

“We need to move to a world where we know much more about our bodies and what's going on so we can get ahead of the problems before they actually cause us to get diseases,” he says.

David has introduced an exciting new longevity theory based on his own research and the top aging scientific breakthroughs known to date. In this conversation, you’ll learn what he’s discovered about aging—he’s “reprogramming cells to be young again”—and the exciting science behind his new book: "Lifespan: The Revolutionary Science of Why We Age — and Why We Don’t Have To.”

Enjoy the show!

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Episoder(1459)

What Biohacking Borrows from Shamanism – Manvir Singh, Ph.D. : 967

What Biohacking Borrows from Shamanism – Manvir Singh, Ph.D. : 967

IN THIS EPISODE OF THE HUMAN UPGRADE™...… you’ll find out about the relevance of shamanism in a modern world and why high performers are turning toward shamanic practices to get ahead.The show’s guest, Manvir Singh, Ph.D., is an anthropologist at the Institute for Advanced Study in Toulouse, France. He studies universal or near-universal cultural practices, including music, shamanism, and witchcraft. For the past seven years, he’s conducted ethnographic fieldwork in Indonesia. He recently wrote an article in WIRED magazine titled, “The Shamanification of the Tech CEO,” noting some curious parallels.“Silicon Valley austerity continues to grow more extreme. By 2020 intermittent fasting was no longer enough, and dopamine fasting—an abstention not just from food but from any form of stimulation, including music, eye contact, and playing Magic: The Gathering—had taken off. These self-denial fads are often touted as biohacking innovations. Yet as an anthropologist who has studied austerity in some of the most remote regions of the world, I see them as part of a larger pattern: the self-shamanification of tech CEOs.”“Analyzing an old dataset of 43 nonindustrial societies, I found that shamans in 81 percent of the societies observed prohibitions on food, sex, or social contact. Given that these data were collated from reports by travelers and anthropologists, they are probably an underestimate. Silicon Valley deprivation, it turns out, is less a strange, new development and more the most recent manifestation of a ubiquitous shamanic practice.”This conversation gets into:shamanism in generalthe cultural significance of shamanshow shamanic practices have made their way into modern culturewhy humans think they need shamans—or similar “magic” or “other” beings More about Manvir Singh, Ph.D.: Manvir earned a Ph.D. in Human Evolutionary Biology at Harvard University and a Sc.B. with Honors in Human Biology: Evolution, Environment, & Ecosystems at Brown University. He’s received multiple awards, honors, grants and fellowships—from Fulbright Scholarship to visiting scholar and research fellow. He’s written more than a dozen peer-reviewed journal articles and more than a dozen articles for general audiences. He gives talks domestically and internationally on the topic of shamans.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Control Blood Glucose: https://pendulumlife.com, sign up for membership to get monthly supply delivery, use code DAVE20 to save $20 on your first shipmentIncrease BDNF and Support Neurogenesis: Go to https://nootopia.com/davegenius, use code DAVE10 to get an extra 10% offIsometrics for Cardiovascular Health: https://www.zona.com, use code DAVE2022 to get $150 off the Zona PlusSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

16 Aug 20221h 6min

How To Be Your Future Self Right Now – Benjamin Hardy, Ph.D. : 966

How To Be Your Future Self Right Now – Benjamin Hardy, Ph.D. : 966

IN THIS EPISODE OF THE HUMAN UPGRADE™...… you’ll find out how your imagined future directs your behavior right now, rather than your past. You’ll learn how to manage threats to your future self, recognize truths about your future self, and how to take steps to be your future self. You’ll also gain strategies you can start using today for creating and becoming exactly who you want to be in the present moment.Benjamin Hardy, Ph.D., is an organizational psychologist and author of multiple books on how to improve your mindset. He joins the show to explain how you can borrow from your future and actually be that person right now. In his newest book, “Be Your Future Self Now: The Science of Intentional Transformation,” he says, “Research now shows that a person’s past does not drive or dictate their actions and behaviors. Rather, we are pulled forward by our future.” There’s no looking back, only moving ahead. Most people, out of fear, limit their view of the future to a narrow range. Take a dangerous leap to think more broadly. Take cues from your brain.“With neuroscience, the brain is essentially considered a prediction machine,” Ben says. “So, what the brain is always doing is predicting what's going to happen, and learning is essentially just updating its sense of predictions. The brain is always anticipating the future.”Since you’re already thinking about the future, put those thoughts to use in the here and now with 21 actions (7 threats to, 7 truths about, and 7 steps for being your future self) designed to transform yourself. For example:Offset a THREAT: Urgent battles and small goals keep you stuck. To exit the rat race of day-to-day mindset requires a shift in your focus. Face a TRUTH: Failing as your future self is better than succeeding as your current self. The more willing you are to invest in momentary loss and pain directed at a goal, the faster you’ll adapt to the level of your future self. Take a STEP: Schedule your future self. Put the important before the urgent. Once you commit to your Future Self, you’ll be required to be courageous. Choosing freedom over security is an act of courage.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Calm Your Nervous System: Give the sensation of a hug, deep relaxation and better sleep: https://balooliving.com/dave, use code DAVE for a special discountTasty Keto Bread & Chips: https://www.uprisingfood.com/DAVE, use code DAVE to get $10 off the starter bundleSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

12 Aug 20221h 7min

Control Your Mindset with 4 Questions – Legacy Upgrade ft. Byron Katie : 965

Control Your Mindset with 4 Questions – Legacy Upgrade ft. Byron Katie : 965

IN THIS EPISODE OF THE HUMAN UPGRADE™...…a legacy upgrade conversation with Byron Katie will have you digging deep into the work of fine-tuning your mindset. Her keystone practice, The Work, allows you to access the wisdom you already hold inside you. She explains it as a process to “clear the mind.”You’ll ask yourself four questions and apply them to a specific problem you’re facing. Going through these steps gives you perspective and a new way of thinking about what’s causing you distress. Questioning diminishes the power your thoughts have over you. And THAT leads to true freedom.Her work contains elements of therapist, a counselor or a religious leader, though she’s technically not any one of these. She’s been described as a spiritual mentor. As the bestselling author of “Loving What Is: Four Questions That Can Change Your Life," followed by "A Mind at Home with Itself: How Asking Four Questions Can Free Your Mind, Open Your Heart, and Turn Your World Around," her inspirational guidance offers people a different way to think their thoughts so they can change their mindsets and, ultimately, their lives.Her own story of early life success that spiraled into depression, rage, addiction, and self-loathing, sets the foundation for The Work. “The thoughts like, “I’m not good enough. There's something wrong with me," which was true,” Byron explains. “It was my thinking. My thoughts were aimed out at other people. It was their fault. Then when I would say or do something, I would experience the guilt, so I had this vicious circle going of judgment, guilt, judgment, guilt. It was debilitating.”She had to save herself. Several weeks into treatment, she woke up one morning to a state of constant joy that has never left her and four questions clearly in her mind that would lead her out of her own darkness. She’s never been able to truly explain this epiphany, nor has she evangelized it. She realized that when she believed her stressful thoughts, she suffered, but that when she questioned them, she didn't suffer, and that this is true for every human being. She simply shares The Work with people who want to make profound life changes—and has continued this path for nearly 40 years.“I have a lot of people across the globe that are saying their lives are shifting so dramatically they're unrecognizable, but I don't call it The Work for nothing,” she says. “It does take stillness. It takes silence, and it takes being courageous enough to look at the thoughts in your head without trying to change them and accept them the way they are.”WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Kickstart Autophagy: https://timelinenutrition.com/DAVE, use the code ASPREY10 to get 10% off any planMattress Temperature Tech: https://www.eightsleep.com/dave, use code dave to save $250 on the Pod ProSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

9 Aug 202253min

Upgrade Spotlight: Cook Faster, Easier & Better With Light – Brava : 964

Upgrade Spotlight: Cook Faster, Easier & Better With Light – Brava : 964

IN THIS EPISODE OF THE HUMAN UPGRADE™...... you’re going to find out how to cook differently using an innovative kitchen appliance, Brava, that’s got some cool features that will get you excited about making your meals at home—always a good idea!First—what Brava is not. The Brava countertop cooking oven isn’t a microwave, isn’t a toaster oven, and isn’t a convection oven.Instead, it’s a device that cooks with light. Six lamps deliver exact, variable, infrared light waves to your food. Brava synchronizes and controls the amount of power each lamp emits. Simultaneously, the lamps instantly reach full power and turn off just as quickly, creating three independent cooking zones inside the chamber. The top five benefits of this cooking method include: Searing (great for your grass-fed steaks), precision, versatility, speed and quality. Brava also cooks up to three different ingredients at the same time. You can air fry, dehydrate and cook your favorite white rice in it (Bulletproof Diet approved). It’s user- and kid-friendly, so your whole family can be part of a lifestyle that prioritizes food that nourishes your body and ups your energy.Brava’s vice president and professional chef, Travis Rea, led the Brava Culinary Team in developing Brava's patented Pure Light Technology (physicists and mathematicians were in on it, too). He’s on the show to explain the technology behind Brava and how cooking with light will change your entire approach to food.Travis earned a degree in Culinary Arts at the California Culinary Academy. Prior to Brava, he headed the Food Development team at Williams-Sonoma for eight years where he developed nearly 800 private label food products. His experience also includes leadership roles at Revolution Foods and NatureBox. So, he knows the many facets of creating great food.Brava takes out the guesswork of meal planning by offering over 7,000 fully automated recipe programs. This means you can enjoy cooking more because it takes less of your time.SPECIAL OFFER FOR LISTENERS OF THE HUMAN UPGRADE: https://www.brava.com, use code DAVE at checkout to get $200 OFF any Brava set through December 31, 2022. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

6 Aug 202235min

How Whole Body Vibration Hacks Fitness & Fat Loss – Tony Molina : 963

How Whole Body Vibration Hacks Fitness & Fat Loss – Tony Molina : 963

IN THIS EPISODE OF THE HUMAN UPGRADE™...… you’ll learn how whole body vibration works and the many ways it benefits your physiology. It’s the nexus between energy and life, says Tony Molina, a performance optimization expert.“This biohack helps you burn more calories,” he says. “It helps you increase strength and reaction time. You can improve skin and circulation, bone density, pain relief, hormonal changes, posture and balance. It's also a lifelong health and longevity partner.” He’s talking about the Power Plate. He’s a high-altitude and longevity researcher and Senior Research and Development Specialist at the company.“Whole body vibration runs off Isaac Newton's second law, so force equals mass times acceleration,” he explains. “Where acceleration is what’s being increased versus mass. And generally, we focus on the mass, whether we do any kind of strength training, we focus on holding mass or dealing with the mass or changing the mass. With whole body vibration and Power Plate, you’re focusing on the acceleration or the speed change.”Other cool things about whole body vibration:You're changing the formula from conscious effort (like conventional exercise) to subconscious (harmonic vibration).You’re experiencing multiplanar movement that creates an unstable environment that’s proprioceptively challenging. (The nervous system doesn't know what to do, which is a good thing.)Your neuromuscular spindle gets stimulated without the need for the brain even to get involved. (Cognitive confidence!) Your nervous system itself is ramping up safety signals so the brain understands what it needs to do without you consciously having to do anything.Your reflexes improve; your reaction time gets better; your ability to propriocept allows your posture to improve; and you breathe better.Listen on to find out more about whole-body vibration training, therapy, and how it can make you live longer, whatever your fitness level or ability.SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: https://powerplate.com/dave to get 20% off a Power Plate® MOVE (save $659) AND a FREE Power Plate Pulse Massage Gun (valued at $249.99) WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Increase BDNF and Support Neurogenesis: Go to https://nootopia.com/davegenius, use code DAVE10 to get an extra 10% offA Cleaner Nicotine Alternative: https://lucy.co, use code DAVE20 for 20% off your first order of pouches, gums or lozengesCooler Temps for Deeper Sleep: https://www.chilisleep.com/, use code HUMANUPGRADE20 to save 20% on the Dock Pro Sleep System See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

5 Aug 202254min

How to Hack Your Metabolism and Power Your Energy – Michal Mor, Ph.D. : 962

How to Hack Your Metabolism and Power Your Energy – Michal Mor, Ph.D. : 962

IN THIS EPISODE OF THE HUMAN UPGRADE™...…you’ll learn about the critical role metabolism plays in your body’s energy and performance. Important new science findings about human metabolic health shows how you can change your metabolism. To help you make these changes, this episode gives you practical tips and tools for measuring your metabolism and ways to manage it effectively.Guest Michal Mor, Ph.D., co-founded Lumen with her twin sister, Merav Mor, Ph.D., and three long-time entrepreneur friends nearly a decade ago. As Chief of Metabolic Health & Science, Michal’s background includes degree studies in Medical Laboratory Sciences and Physiology with an emphasis on cardiac arrhythmia. The Lumen founders set out to close the gap of what existed in the science and something people could actually use to manage their metabolic health.Both Michal and her twin, Merav, were multiple-year Ironman participants. Athletic performance—and how to improve it—influenced their work with metabolism. Four years of research and development plus more years of validation studies and beta test users went into developing Lumen. Lumen is a hand-held device that accurately measures your metabolism through the breath. It uses a CO2 sensor and flow meter to measure the CO2 concentration in your breath, indicating if your body is in carb or fat burn.“So, this ability to shift between them, it's not only good for athletic performance it's also improving our quality of life,” Michal says. “It enables us to enjoy life to our fullest potential. It's about longevity. It's about being able to achieve our goals, not having those mood swings. This is so much more than improving athletic performance.”Lumen has accumulated a metabolic measurement database with over 20m measurements. These insights have shown how lifestyle habits affect metabolism and the body more than previously thought possible. Listen on to learn how with just one breath in the morning, you can set your metabolism course for the day and then monitor it throughout the day.SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERS: https://lumen.me, use code Asprey50 to get $50 off a Lumen deviceWE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Experience the High Life with Infrared Therapy: https://higherdose.com and use code HUMAN10 for 10% off your entire purchase.Capture Life Force Energy: https://leelaq.com, use discount code DAVE10 to get 10% off sitewideBusiness Growth With SEO: https://www.stephanspencer.com, get a FREE consultationSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

2 Aug 20221h 6min

Mini-Episode: Cool Facts Friday #25

Mini-Episode: Cool Facts Friday #25

In this Episode of The Human Upgrade™...​Cool Facts are quick hits of new human and world science curated into short bursts of information just for you. This fun compilation publishes one Friday a month.Tattoos can help monitor your blood pressure Device that protects against head injuries Upgrading your avocado toastWays to manage the harmful aging-inflammation duo Pee recycling does the soil goodEPISODE SPONSOR: The Eng3 NanoVi device helps repair oxidative stress damage and support the body’s natural repair mechanisms. https://eng3corp.com/DAVE/. Learn more: The Anti-Aging Science Behind the NanoVi Device – Rowena Gates & Hans Eng – #416.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

30 Jul 202212min

How to Fix Your Brain When It’s Tired, Wired and Slow – Matt Gallant & Mr. Noots : 961

How to Fix Your Brain When It’s Tired, Wired and Slow – Matt Gallant & Mr. Noots : 961

IN THIS EPISODE OF THE HUMAN UPGRADE™... … you’ll find out why aging and stress are the major contributors to neurodegenerative diseases in your lifetime, what you can do to stave off the effects, and how you can kickstart your brain into functioning at a way higher level.You’ll also learn about:BDNF (Brain-Derived Neurotrophic Factor) and ways to increase itOptions for how you can support your brain’s neurogenesisHow certain mushrooms and collagen can be used to increase your cognitive function—so you can focus, concentrate and be more creativeHow customized nootropics can help you reach peak mental performance Matt Gallant keeps coming back on the show to introduce innovative supplements that work with your brain and body. We’ve talked about nootropics, psychobiotics, magnesium, enzymes, blood sugar, gut health and more. As co-founder of BiOptimizers, Matt makes important connections within body systems and finds unique ways to maximum human performance. After a personal health scare with his own brain, he’s turned his professional attention to hacking and upgrading the brain in as many ways as possible.Most people’s brains aren't at 100% due to many factors, he says, like lack of sleep, chronic high stress, an inadequate diet, and overuse of certain drugs and prescriptions.Mr. Noots, (scientist Mark Effinger) teamed up with Matt on this quest to support brain health and improve cognitive function. After a childhood exploring everything science, chemistry and physics, he joined the US Air Force and became an endurance athlete and bodybuilder. His life, like Matt’s, took an unexpected turn and he struggled with health issues. It took creative, performance-enhancing nutrition to get himself well. He’s now Chief Product Officer for the mind-enhancing compounds and stacks of nootropics at Nootopia and works side-by-side with Matt.Their newest product, CollaGenius, combines powerful mushroom extracts and collagen into a formula specifically to energize your brain and body. Collagen improves skin health, relieves joint issues, strengthens hair and nails, and prevents bone loss—and it also does your brain a lot of good. And here’s what the mushrooms do for you in the right amounts. That’s the key principle—the dose creates the effect. Lion’s Mane: Boosts BDNFChaga: A natural anti-inflammatory that supports immunityReishi: Alleviates stressCordyceps: Elevates athletic performance and maximizes brain health Together, Matt and Mr. Noots continue pushing limits and finding ways to make your brain operate at its highest capacity. SPECIAL OFFER FOR THE HUMAN UPGRADE LISTENERSGo to https://nootopia.com/davegenius, use code DAVE10 to get an extra 10% off.WE APPRECIATE OUR PARTNERS. CHECK THEM OUT!Mineral-Rich Salt with Micronutrients: https://oryxdesertsalt.com, learn more at the website and purchase through Whole FoodsA Cleaner Nicotine Alternative: https://lucy.co, use promo code DAVE20 for 20% off your first order of pouches, gums or lozenges.Isometrics for Cardiovascular Health: https://www.zona.com, use code DAVE2022 to get $150 off the Zona Plus See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

29 Jul 202258min

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