Relationship Goals: Your Gut Microbiome and Immune Function – Kiran Krishnan, Ph.D., with Dave Asprey : 864

Relationship Goals: Your Gut Microbiome and Immune Function – Kiran Krishnan, Ph.D., with Dave Asprey : 864

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IN THIS EPISODE OF BULLETPROOF RADIO...

Research microbiologist Kiran Krishnan, Ph.D., explores the world of microorganisms inside your body. He studies the human microbiome and knows just how much inflammation damages your gut and how your immune system fixes it.

He’s particularly adept at explaining practical ways to apply the latest science he’s uncovering.

His expertise lies in the newest frontier in microbiology—gut commensal spore bacteria. He partners with Just Thrive Health on prebiotics, probiotics and other gut health product development.

When he was on the show previously, we got into probiotics and immune health. (Don’t miss those! Support Immune Health in Two Steps: Modulate Gut Bacteria & Neutralize Inflammation – #677 and Armor-Plated Immortal Probiotics from Space – #629. This time, he makes connections between your microbiome and immune function.

“The inflammatory response is the biggest driver of gut related damage that occurs,” Kiran says. “You can also eat foods that are absolutely toxigenic to your microbiome.”

The good news? Up to 80 percent of your immune system lies in your digestive tract, Kiran explains. “Your immune system is there, ready and waiting to help with the situation.”

In this episode, you’ll learn that lipopolysaccharide (LPS) is the unknown villain of virtually everything. Kiran says it causes damage to the brain, contributes to metabolic disease, drives Alzheimer’s, Parkinson’s, and is the No. 1 driver of diabetes (to name a few).

“LPS is the most pervasive toxin we have to deal with and it’s an endotoxin, which is a key because we can’t get away from it,” Kiran says.

Kiran has a strict research background in the fields of molecular medicine and microbiology. For nearly 20 years, he’s conducted dozens of human clinical trials in human nutrition through his research organization: Clinical Research Organization.

His recently published leaky gut study showed reversal of gut enteropathy within 30 days. He’s now involved with a longer, more extensive leaky gut trial.

His current research also includes nine other ongoing human clinical trials. Some test the effect of gut commensal spore probiotics on conditions like Thyroid/Hashimoto’s, Irritable Bowel Syndrome and liver failure.

Listening to this extensive interview, you’ll find out cool stuff, like what faecalibacterium prausnitzii is and how it helps you.

“We all have all kinds of damage occurring in our large bowel all the time,” Kiran says. “But if you have faecalibacterium, it's constantly repairing it. If you don't have faecalibacterium, at some point, the damage overcomes the repair and you start getting significant inflammation in lining which then puts you at risk for things like inflammatory bowel disease. Right, so we're constantly battling this state of damage, oxidative stress, inflammation, and all that, and then repair recovery and so on. And then as it turns out, microbes are so important for that repair and recovery phase.”

You’ll also gain new perspective of your own body biomes and the broader world: “I've always referred to the human system as a walking, talking rainforest,” Kiran says. “We are a holo-biome which is a super organism. We are an organism made up of a collective of organisms that together in a certain balance will function and work. But we are also in constant osmosis with the ecosystem, and we're designed to be that way.”

Another positive for your gut and immune health is the vast number of microbial genes in your system.

“We have such limited amount of genetic capability as a species,” Kiran says. “We barely have enough genetic material as an earthworm does, and so we're not that cool or sophisticated. What makes us as sophisticated as we are, is the two and a half million or so microbial genes in our system. And so, being able to outsource functionality to microbes is a big part of being human. There are sets of organisms that we have outsourced through the course of evolution, the ability to modulate and monitor the rest of the microbiome. We're finding that when you start putting in these microbes back into your system, you really start getting the positive changes. They start refereeing the ecosystem and making things more balance and improved.”

Enjoy! And get more resources at Dave.Asprey/podcasts. Got a comment, idea or question for the podcast? Submit via this form.

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Episoder(1459)

#51 Transhumanism, Technology & the Future with Natasha Vita-More

#51 Transhumanism, Technology & the Future with Natasha Vita-More

This episode stretches the boundaries of biohacking by looking at the futurist ideology and movement called transhumanism. Natasha Vita-More, an American designer, theorist and author, joined me on this episode to discuss the possible transformation of the human condition by developing technologies that enhance intellectual, physical, and psychological capacities.  Natasha Vita-more is co-editor and author of The Transhumanist Reader: Classical and Contemporary Essays on the Science, Technology and Philosophy of the Human Future and designer and author of "Primo Posthuman," a pioneering future whole body prototype. Vita-More is a professor at the University of Advancing Technology, and a Fellow of the Institute for Ethics and Emerging Technologies and the Hybrid Reality Institute. She is currently Chairman of the Board of Directors of Humanity+. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

23 Jul 201349min

#50 New Bulletproof iPhone App, Food Sensitivities & HRV with Ronda Collier from SweetWater Health

#50 New Bulletproof iPhone App, Food Sensitivities & HRV with Ronda Collier from SweetWater Health

The 50th episode of Bulletproof Executive Radio introduces you to a brand new free iPhone app called Bulletproof(R) Food Sense and to the scientist who made it all happen.  Today’s interview is with long time biohacker and founder of Sweetwater Health™, Ronda Collier. Ronda is putting her more than 25 years of experience in high tech to work at SweetWater Health™, where they are looking at the signal coming from the human heart, and instead of seeing beats per minute or simple heart rate variability, seeing a huge pool of big data just waiting to be analyzed using Ronda’s crazy advanced math skills. There is a lot more information in your heartbeat than you’d think – stress levels are just the beginning. By applying mobile health monitoring and stress management with medical research techniques, SweetWater Health is creating some very advanced, very easy to use biohacking technologies. My experience as a bio hacker who used to weigh 300 pounds and really struggled with food cravings, is that every single person has a set of things in their environment or their food that makes them weak. SweetWater Health and Bulletproof Executive just partnered to create the free Bulletproof(R) Food Sense iPhone app to help you find your personal kryptonite by using the phone’s onboard sensors to detect your hidden food sensitivities.   You can also get an amazingly full-featured version of the app that works with a chest strap to measure and track your heart rate variability all day long and use complex algorithms to quantify your food, stress, and overall health. Click here to download your free Bulletproof Food Sense app from the Apple iTunes store. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

16 Jul 201348min

#49 Q & A Eggs, Butter & Zen - Podcast

#49 Q & A Eggs, Butter & Zen - Podcast

About once a month, I set aside a whole podcast to answer questions from the Bulletproof community. It's all about answering your very best questions, sourced from e-mail, Facebook, Twitter, the Bulletproof forum and the blog! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

10 Jul 201359min

#48 “Fat Burning Man,” Abel James and Bulletproof Exec Unite

#48 “Fat Burning Man,” Abel James and Bulletproof Exec Unite

This podcast is with Abel James – a #1 best-selling author, fat loss coach, musician, radio show host, and veritable health crusader. Abel also runs the extremely popular “Fat Burning Man” show – which is one of the top health podcasts on iTunes.  A former strategic advisor to the food and beverage industry, Abel now acts as a consumer advocate who exposes the truth behind deceptive marketing practices, misleading corporate propaganda, and powerful special interests that have accelerated the worldwide obesity epidemic and health crisis. Abel harnesses the techniques he developed for the Lean Body System to achieve extremely compelling results in fat loss and health for his clients and the community. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

3 Jul 201356min

#47 Biohacking Cows, Bulletproof Dairy and Probiotics with Natural Health Expert, Jordan Rubin

#47 Biohacking Cows, Bulletproof Dairy and Probiotics with Natural Health Expert, Jordan Rubin

Jordan Rubin is one of America’s most recognized and respected natural health experts. He is the author of the New York Times best selling book, The Maker’s Diet, as well as the author of 19 other health related titles, including his latest work Perfect Weight America. An international motivational speaker, Jordan hosts the weekly television show Extraordinary Health that reaches more than 30 million households worldwide. He is Founder and CEO of Garden of Life, a leading health and wellness company committed to empowering extraordinary health with whole food based supplements, functional foods, and founder of Beyond Organic. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

24 Jun 201349min

#46: Reichart Von Wolfsheild - Bulletproof Your Systems

#46: Reichart Von Wolfsheild - Bulletproof Your Systems

Reichart Von Wolfsheild, is a co-host on History Channel’s Invention USA.  He is a technologist, inventor, artist and futurist. Starting in his teens, he designed and built a computer CPU from scratch. In the early 1980s, while helping pioneer music videos for the then-fledgling network, MTV, he started his first successful technology company developing Artificial Intelligence applications. Blending his talents from several fields he made history conceiving one of the first multi-player modem video games, kicking off a franchise. He has designed everything from toys to weapons and developed more than 120 products for companies such as Boeing, Disney, Dreamworks and Mattel, and is always looking for the next fun challenge. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

20 Jun 201346min

#45: Q & A More on Coffee, Kale, & Adrenal Fatigue

#45: Q & A More on Coffee, Kale, & Adrenal Fatigue

Questions Asked in the Podcast:   1:20 What is the best way to store Bulletproof Coffee and can you pre-grind it and store it? 4:10 For people who like to do heavy workouts several times a week what do you recommend for  recovery and muscle building? 5:30 What's the deal with drugs, specifically marijuana? Is it Bulletproof? 7:14 What about marijuana by products like Hemp protein powder or Hemp seed oil? 8:44 How can I get a Bulletproof T-shirt like the one Dave had on the Joe Rogan Experience? (bulletproofexec.com/shirts) 10:01 What are the differences between the new Bulletproof Upgraded Brain Octane Oil and the Bulletproof MCT Oil? Does the Octane Oil replace the MCT Oil or is it mean to be an addition? 13:10 Can I add the Upgraded Whey into my coffee without pushing myself out of ketogenesis? 14:28 Why is there no Certified Organic label on the MCT Oil? 15:10 How do you make a proper iced ,and blended iced, Bulletproof coffee without the fat sticking to the sides or globbing together? 16:22 Is taking Bioidentical growth hormone safe? 17:34 In the Kale Shake you list raw eggs as a potential addition, would eggshells work as well? 18:49 I massage my kale before blending or sauteing it, do I still need to stew this before steaming, or should I just cut the massage out altogether? Also are the oxalates in baby kale less? 19:43 Should I make a kale shake in addition to or in lieu of Bulletproof coffee? 20:35 Are kale chips Bulletproof? 22:19 Why is Bulletproof Coffee NOT affected by the coffee fungus problem? 24:21 Changing your diet making you stinky? 26:40 Activated charcoal and its benefits 30:24 How do I recover if I have a cheat meal from the Bulletproof Diet? 32:03 How to schedule Bulletproof Coffee and Diet around a crazy sleep schedule 35:30 Can I substitute kale with broccoli to avoid the toxins? 35:50 Adrenal Fatigue, how do you know you have it, what are some common causes, and how do I make it better? 39:35 How do you gain weight while Bulletproof? 42:35 Biohacks of the week and other conversation...   See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

10 Jun 201349min

Bonus: Client Review with Jonathan Kos

Bonus: Client Review with Jonathan Kos

Jonathan Kos is an IT professional and a recent follower of the Bulletproof Diet.  He is a 44 year old IT professional . At 6' 3" and a former college athlete that played football, competitive ice hockey up until the age of 25 he was an extremely fit 220 lbs and my coaches wanted me up to 275 or so to play the defensive line so I was eating literally non stop to put weight on. After college he dropped down to around 200 lbs and eventually settled at for me was a healthy 235.  As he got older and more settled in his job, his weight climbed and he couldn’t keep his weight in check with exercise alone and he started to have to diet he was up to 300 lbs and was exercising more that ever but the weight didn’t come off. After he met his wife, exercise was out the window, a carb heavy diet was in, and his weight ballooned up to 365lbs. He was about to give up until he heard Tait Fletcher on Joe Rogan's podcast mentioning Bulletproof ® Coffee and he gave it a shot. He lost 45lbs in 45 days, and is here to share his experience with you.  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

3 Jun 201311min

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