Relationship Goals: Your Gut Microbiome and Immune Function – Kiran Krishnan, Ph.D., with Dave Asprey : 864

Relationship Goals: Your Gut Microbiome and Immune Function – Kiran Krishnan, Ph.D., with Dave Asprey : 864

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IN THIS EPISODE OF BULLETPROOF RADIO...

Research microbiologist Kiran Krishnan, Ph.D., explores the world of microorganisms inside your body. He studies the human microbiome and knows just how much inflammation damages your gut and how your immune system fixes it.

He’s particularly adept at explaining practical ways to apply the latest science he’s uncovering.

His expertise lies in the newest frontier in microbiology—gut commensal spore bacteria. He partners with Just Thrive Health on prebiotics, probiotics and other gut health product development.

When he was on the show previously, we got into probiotics and immune health. (Don’t miss those! Support Immune Health in Two Steps: Modulate Gut Bacteria & Neutralize Inflammation – #677 and Armor-Plated Immortal Probiotics from Space – #629. This time, he makes connections between your microbiome and immune function.

“The inflammatory response is the biggest driver of gut related damage that occurs,” Kiran says. “You can also eat foods that are absolutely toxigenic to your microbiome.”

The good news? Up to 80 percent of your immune system lies in your digestive tract, Kiran explains. “Your immune system is there, ready and waiting to help with the situation.”

In this episode, you’ll learn that lipopolysaccharide (LPS) is the unknown villain of virtually everything. Kiran says it causes damage to the brain, contributes to metabolic disease, drives Alzheimer’s, Parkinson’s, and is the No. 1 driver of diabetes (to name a few).

“LPS is the most pervasive toxin we have to deal with and it’s an endotoxin, which is a key because we can’t get away from it,” Kiran says.

Kiran has a strict research background in the fields of molecular medicine and microbiology. For nearly 20 years, he’s conducted dozens of human clinical trials in human nutrition through his research organization: Clinical Research Organization.

His recently published leaky gut study showed reversal of gut enteropathy within 30 days. He’s now involved with a longer, more extensive leaky gut trial.

His current research also includes nine other ongoing human clinical trials. Some test the effect of gut commensal spore probiotics on conditions like Thyroid/Hashimoto’s, Irritable Bowel Syndrome and liver failure.

Listening to this extensive interview, you’ll find out cool stuff, like what faecalibacterium prausnitzii is and how it helps you.

“We all have all kinds of damage occurring in our large bowel all the time,” Kiran says. “But if you have faecalibacterium, it's constantly repairing it. If you don't have faecalibacterium, at some point, the damage overcomes the repair and you start getting significant inflammation in lining which then puts you at risk for things like inflammatory bowel disease. Right, so we're constantly battling this state of damage, oxidative stress, inflammation, and all that, and then repair recovery and so on. And then as it turns out, microbes are so important for that repair and recovery phase.”

You’ll also gain new perspective of your own body biomes and the broader world: “I've always referred to the human system as a walking, talking rainforest,” Kiran says. “We are a holo-biome which is a super organism. We are an organism made up of a collective of organisms that together in a certain balance will function and work. But we are also in constant osmosis with the ecosystem, and we're designed to be that way.”

Another positive for your gut and immune health is the vast number of microbial genes in your system.

“We have such limited amount of genetic capability as a species,” Kiran says. “We barely have enough genetic material as an earthworm does, and so we're not that cool or sophisticated. What makes us as sophisticated as we are, is the two and a half million or so microbial genes in our system. And so, being able to outsource functionality to microbes is a big part of being human. There are sets of organisms that we have outsourced through the course of evolution, the ability to modulate and monitor the rest of the microbiome. We're finding that when you start putting in these microbes back into your system, you really start getting the positive changes. They start refereeing the ecosystem and making things more balance and improved.”

Enjoy! And get more resources at Dave.Asprey/podcasts. Got a comment, idea or question for the podcast? Submit via this form.

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Episoder(1459)

#59 Hacking Productivity, Forming Habits & 'Lift' iPhone App, With Tony Stubblebine

#59 Hacking Productivity, Forming Habits & 'Lift' iPhone App, With Tony Stubblebine

Learn how to unlock your Bulletproof potential from the CEO of the habit-building app, Lift. Tony Stubblebine shares his take on what habits are good to form, and how to develop and sustain those habits by creating a supportive lifestyle. Tony and I also dug deep into the performance and emotional aspects of being a CEO. If you are a productivity hack or a high performing businessperson, than you do not want to miss this episode! Tony Stubblebine co-founded Lift based on the idea that positive reinforcement and community support could be deployed universally to help people achieve their goals. Prior to Lift, he was the founder and CEO of CrowdVine Event Social Networks, which builds simple and powerful software to help people connect and meet. He was also a part of the Wesabe launch team, Director of Engineering at Odeo.com and O'Reilly Media, and authored Regular Expression Pocket Reference. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

4 Sep 201354min

#58 Food Choices, Willpower & Sugar Cravings with Michael Fishman

#58 Food Choices, Willpower & Sugar Cravings with Michael Fishman

Take control of your food choices, understand your willpower, and combat sugar cravings by listening to this episode with expert health marketing advisor, Michael Fishman. You will hear how Michael radically changed his diet to be a healthier, more in control and happier version of himself, and how you can do that too. Michael Fishman is a leading advisor on marketing, positioning and strategy for health, wellness and personal development businesses and personalities such as Rodale's Prevention and Men's Health publishing brands, Dr. Andrew Weil, Dr. Mark Hyman, Dr. Christiane Northrup, Dr. Dean Ornish and many others. Michael is also a highly sought after speaker on how marketing language, customer care and work culture combine to take companies from merely good to the beloved best at what they do. He created the annual Consumer Health Summit, which is the preeminent invitational forum for CEOs, entrepreneurs and marketing leaders in health and wellness. He is also a co-founder of BehaviorCon, a conference on marketing and consumer psychology.  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

27 Aug 201347min

#57 Becoming Alpha, Dispelling Myths & Making Changes, with Adam Bornstein

#57 Becoming Alpha, Dispelling Myths & Making Changes, with Adam Bornstein

As a top health and fitness editor and best-selling author, Adam Bornstein came on the show to share what it means to be ‘Alpha’ and how being bulletproof is possible for everyone. In this episode, Adam and I discuss our shared egg obsession, whether cheat days are helpful or harmful, and how mental barriers keep you from achieving the best version of yourself. You will even get a glimpse into the workings of mainstream media, research, and health journalism. Adam Bornstein is a biohacking, solutions oriented machine! Adam has been named “one of the most influential people in health.” He’s a long time health and fitness writer and editor for magazines like Men’s Health and Livestrong, and best-selling author of four fitness books, including his most recent book “Man 2.0 Engineering the Alpha: A Real World Guide to an Unreal Life: Build More Muscle. Burn More Fat. Have More Sex” See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

20 Aug 201354min

#56 Biohacking Apocalypse Survival, Stress Inoculation & Shamans, with Sam Sheridan

#56 Biohacking Apocalypse Survival, Stress Inoculation & Shamans, with Sam Sheridan

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13 Aug 201350min

#55 Fitness, Nutrition & Bulletproof Habits, with High Performance Health Coach, Yuri Elkaim

#55 Fitness, Nutrition & Bulletproof Habits, with High Performance Health Coach, Yuri Elkaim

From professional athlete to high performance health coach, Yuri Elkaim joins us today to talk about (almost) all things Bulletproof. In his goal to help 10,000,000 people become healthier, Yuri will share his take on raw food, the “fruit & veg” argument, exercise vs. rest, habits, and more! If you are an athlete (or biohacker) looking for 1 or 2 tips to take your performance to the next level, this is the show for you. Yuri Elkaim is a registered holistic nutritionist, fitness expert, and highly sought after high performance health coach. He’s also a former professional soccer player and served as the Head Strength & Conditioning and Nutrition Coach for men’s soccer at the University of Toronto for 7 seasons. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

9 Aug 201346min

#54 Neurofeedback Technology, Best Biohack Yet, with Dr. Valdeane Brown

#54 Neurofeedback Technology, Best Biohack Yet, with Dr. Valdeane Brown

This episode is all about the most effective biohack I’ve experience yet – NeurOptimal® brain training. Dr. Valdeane Brown, Founder of NeurOptimal, came on the show to explain how this technology takes your performance to uncharted levels! The NeurOptimal brain trainer is the most powerful and affordable neurofeedback technology available. You will get to hear about the EEG technology and how it transforms your brain, upgrade athletic performance, and even help with migraines, PTSD, and abusive relationships. Does this sound too good to be true? Listen for yourself… Dr. Valdeane W. Brown is an internationally recognized "trainer of neurofeedback trainers", who has taught and consulted widely on personal and organizational transformation. With a Ph.D. in Clinical Psychology and a background in math, physics, computer programming, philosophy, yoga, meditation and martial arts, Dr. Brown brings a presence and precision to his work. This is further informed by a profound sense of compassion, a facility with energy dynamics and a deep commitment to revealing the elegant simplicity inherent in learning and transformation. Developer of the Five Phase Model and co-creator with his wife Sue of the Period 3 Approach to Clinical Neurofeedback, Dr. Brown has realized his vision of a truly comprehensive training system in NeurOptimal. His vision in bringing NeurOptimal to the world is to make personal transformation effortless and available to all. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

6 Aug 20131h 1min

#53 Raw Vegan to Bulletproof Meat Eater - a beneficial transformation, with Kristen 'Raw' Suzanne

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1 Aug 201357min

#52 – Sex, Sex Culture & Sex at Dawn with Christopher Ryan - Podcast

#52 – Sex, Sex Culture & Sex at Dawn with Christopher Ryan - Podcast

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