Communicable E1 - Late-breaker clinical trial results from ESCMID Global 2024: Should they change your practice?
Communicable10 Mai 2024

Communicable E1 - Late-breaker clinical trial results from ESCMID Global 2024: Should they change your practice?

CMI Communications editors Angela Huttner, Marc Bonten, and Erin McCreary discuss late-breaker clinical trials presented at ESCMID Global (ECCMID) in Barcelona, providing insights into the trials’ designs, results, and implications. The DOTS trial compared two doses of long-acting dalbavancin to standard of care in patients with complicated S. aureus bacteremia. GAME-CHANGER compared cefiderocol to standard of care for gram-negative infections. PediCAP compared oral step-down therapy with amoxicillin with or without clavulanic acid at shorter durations to the current WHO-recommended standard of five days of intravenous antibiotic therapy in children with severe pneumonia. Additional results from the MULTICAP and CLEEN trials, the CAMERA-2 follow-on in vitro analysis, and the Burkina Faso Escherichia coli transmission study are also discussed. Episode peer-reviewed by Dr. Yousra Kherabi.

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Episoder(61)

Communicable E60: Quarterly catch-up (August 2026 edition)

Communicable E60: Quarterly catch-up (August 2026 edition)

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Communicable E59: 'Ask me anything' – EUCAST and CLSI leadership explain

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Communicable E58: Reducing hospital-acquired pneumonia – the HAPPEN trial and how it happened

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12 Jul 54min

Communicable E57: We will make you love PK/PD, part 2

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28 Jun 47min

Communicable E56: Frequentist vs Bayesian for clinical trial analysis – 99% probability you’ll want to listen to this

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14 Jun 1h 5min

Communicable E55: Bonus episode – Bundibugyo ebolavirus outbreak

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7 Jun 57min

Communicable E54: ESCMID Global Late Breakers, part 2

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31 Mai 55min

Communicable E53: ESCMID Global Late Breakers, part 1

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The ESCMID Global Late Breakers series returns to Communicable! Five CMI Communications editors – Marc Bonten, Josh Davis, Angela Huttner, Anne-Grete Märtson, and Erin McCreary – handpicked five late-...

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