Essentials: Understanding & Treating Addiction | Dr. Anna Lembke
Huberman Lab26 Jun 2025

Essentials: Understanding & Treating Addiction | Dr. Anna Lembke

In this Huberman Lab Essentials episode, my guest is Dr. Anna Lembke, MD, Chief of the Stanford Addiction Medicine Dual Diagnosis Clinic at Stanford University School of Medicine. We discuss how dopamine drives reward, motivation and addictive behaviors. Dr. Lembke explains the concept of the pleasure-pain balance of dopamine and how this cycle plays a key role in the development and persistence of addiction. We also discuss some of the challenges of addiction recovery, including withdrawal, relapses and the potential benefits of psychedelic-assisted therapy. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Wealthfront**: https://wealthfront.com/huberman BetterHelp: https://betterhelp.com/huberman **This experience may not be representative of the experience of other clients of Wealthfront, and there is no guarantee that all clients will have similar experiences. Cash Account is offered by Wealthfront Brokerage LLC, Member FINRA/SIPC. The Annual Percentage Yield (“APY”) on cash deposits as of December 27,‬ 2024, is representative, subject to change, and requires no minimum. Funds in the Cash Account are swept to partner banks where they earn the variable‭ APY. Promo terms and FDIC coverage conditions apply. Same-day withdrawal or instant payment transfers may be limited by destination institutions, daily transaction caps, and by participating entities such as Wells Fargo, the RTP® Network, and FedNow® Service. New Cash Account deposits are subject to a 2-4 day holding period before becoming available for transfer. Timestamps 00:00:00 Anna Lembke 00:00:15 Dopamine, Reward & Movement 00:01:54 Baseline Dopamine; Genetics, Temperament & Addiction 00:05:24 Addiction, Modern Life & Boredom 00:07:18 Sponsor: AG1 00:08:55 Pleasure-Pain Balance, Dopamine, Addiction 00:14:17 Resetting Dopamine, Substance or Behavior Recovery, Tool: 30-Day Abstinence 00:16:04 Relapse, Addiction, Reflexive Behavior, Empathy 00:20:17 Triggers, Relapse, Dopamine 00:23:15 Sponsor: Wealthfront & BetterHelp 00:26:04 Shame, Truth Telling & Recovery 00:28:26 Addiction, Psychedelic-Assisted Therapy, Psilocybin, MDMA 00:33:29 Social Media & Addiction, Tool: Intentionality Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

Episoder(402)

Essentials: Control Sugar Cravings & Metabolism with Science-Based Tools

Essentials: Control Sugar Cravings & Metabolism with Science-Based Tools

In this Huberman Lab Essentials episode, I explain how the body senses and uses sugar, and why understanding those mechanisms can help reduce sugar cravings. I discuss different types of sugar and how...

30 Apr 33min

Male Roles, Obligations and Options for Building a Fulfilling Life | Scott Galloway

Male Roles, Obligations and Options for Building a Fulfilling Life | Scott Galloway

Scott Galloway is a professor of marketing at New York University's Stern School of Business. We discuss masculine roles and obligations of past, present and future. We explore which are timeless and ...

27 Apr 2h 36min

Essentials: The Neuroscience of Speech, Language & Music | Dr. Erich Jarvis

Essentials: The Neuroscience of Speech, Language & Music | Dr. Erich Jarvis

In this Huberman Lab Essentials episode, my guest is Dr. Erich Jarvis, PhD, a professor and Head of the Laboratory of Neurogenetics of Language at Rockefeller University and an investigator at the How...

23 Apr 39min

How to Better Regulate Your Emotions | Dr. Marc Brackett

How to Better Regulate Your Emotions | Dr. Marc Brackett

Dr. Marc Brackett, PhD, is founding director of the Yale Center for Emotional Intelligence and a professor in the Child Study Center at Yale University. We discuss the science of emotion regulation an...

20 Apr 2h 27min

Essentials: Understand & Improve Memory Using Science-Based Tools

Essentials: Understand & Improve Memory Using Science-Based Tools

In this Huberman Lab Essentials episode, I explain how memories are formed and how key neurochemicals, such as adrenaline, can be leveraged to enhance memory formation. I also share science-based prot...

16 Apr 40min

How Women Can Improve Their Fertility & Hormone Health | Dr. Natalie Crawford

How Women Can Improve Their Fertility & Hormone Health | Dr. Natalie Crawford

Dr. Natalie Crawford, MD, is a double board-certified OB-GYN and reproductive endocrinologist. We discuss how to improve hormone health at any age and the importance of fertility markers not just for ...

13 Apr 2h 36min

Essentials: The Biology of Aggression, Mating & Arousal | Dr. David Anderson

Essentials: The Biology of Aggression, Mating & Arousal | Dr. David Anderson

In this Huberman Lab Essentials episode, my guest is Dr. David Anderson, PhD, a professor of biology at the California Institute of Technology (Caltech) and an investigator at the Howard Hughes Medica...

9 Apr 38min

Cultivating Awe & Emotional Connection in Daily Life | Dr. Dacher Keltner

Cultivating Awe & Emotional Connection in Daily Life | Dr. Dacher Keltner

Dr. Dacher Keltner, PhD, is a professor of psychology at the University of California, Berkeley, and a leading expert on the science of emotions and human connection. We discuss the science of awe—wha...

6 Apr 2h 20min

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