Essentials: Understanding & Treating Addiction | Dr. Anna Lembke
Huberman Lab26 Jun 2025

Essentials: Understanding & Treating Addiction | Dr. Anna Lembke

In this Huberman Lab Essentials episode, my guest is Dr. Anna Lembke, MD, Chief of the Stanford Addiction Medicine Dual Diagnosis Clinic at Stanford University School of Medicine. We discuss how dopamine drives reward, motivation and addictive behaviors. Dr. Lembke explains the concept of the pleasure-pain balance of dopamine and how this cycle plays a key role in the development and persistence of addiction. We also discuss some of the challenges of addiction recovery, including withdrawal, relapses and the potential benefits of psychedelic-assisted therapy. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Wealthfront**: https://wealthfront.com/huberman BetterHelp: https://betterhelp.com/huberman **This experience may not be representative of the experience of other clients of Wealthfront, and there is no guarantee that all clients will have similar experiences. Cash Account is offered by Wealthfront Brokerage LLC, Member FINRA/SIPC. The Annual Percentage Yield (“APY”) on cash deposits as of December 27,‬ 2024, is representative, subject to change, and requires no minimum. Funds in the Cash Account are swept to partner banks where they earn the variable‭ APY. Promo terms and FDIC coverage conditions apply. Same-day withdrawal or instant payment transfers may be limited by destination institutions, daily transaction caps, and by participating entities such as Wells Fargo, the RTP® Network, and FedNow® Service. New Cash Account deposits are subject to a 2-4 day holding period before becoming available for transfer. Timestamps 00:00:00 Anna Lembke 00:00:15 Dopamine, Reward & Movement 00:01:54 Baseline Dopamine; Genetics, Temperament & Addiction 00:05:24 Addiction, Modern Life & Boredom 00:07:18 Sponsor: AG1 00:08:55 Pleasure-Pain Balance, Dopamine, Addiction 00:14:17 Resetting Dopamine, Substance or Behavior Recovery, Tool: 30-Day Abstinence 00:16:04 Relapse, Addiction, Reflexive Behavior, Empathy 00:20:17 Triggers, Relapse, Dopamine 00:23:15 Sponsor: Wealthfront & BetterHelp 00:26:04 Shame, Truth Telling & Recovery 00:28:26 Addiction, Psychedelic-Assisted Therapy, Psilocybin, MDMA 00:33:29 Social Media & Addiction, Tool: Intentionality Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

Episoder(376)

Essentials: Micronutrients for Health & Longevity | Dr. Rhonda Patrick

Essentials: Micronutrients for Health & Longevity | Dr. Rhonda Patrick

In this Huberman Lab Essentials episode, my guest is Dr. Rhonda Patrick, PhD, a biomedical scientist and a leading health educator focused on nutrition, aging and general health. We discuss four key ...

1 Jan 40min

Defining Healthy Masculinity & How to Build It | Terry Real

Defining Healthy Masculinity & How to Build It | Terry Real

Terry Real is a therapist and best-selling author expert on male emotional health and how men can build the skills for healthy relating to others: in relationships, work, friendships and to themselves...

29 Des 20252h 50min

Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

Essentials: How to Optimize Your Hormones for Health & Vitality | Dr. Kyle Gillett

In this Huberman Lab Essentials episode, my guest is Dr. Kyle Gillett, MD, a dual board-certified physician in family medicine and obesity medicine and an expert in optimizing hormone levels to improv...

25 Des 202542min

Transform Pain & Trauma Into Creative Expression | David Choe

Transform Pain & Trauma Into Creative Expression | David Choe

David Choe is a world-renowned artist, writer, podcaster and TV host. He tells how as a child, he was made to believe he was destined for greatness but also that he was a complete disgrace, leading hi...

22 Des 20253h 54min

Essentials: How to Set & Achieve Goals

Essentials: How to Set & Achieve Goals

In this Huberman Lab Essentials episode, I explain how to use science-based tools to better set and achieve goals. I discuss the neuroscience of goal pursuit and how dopamine and visual attention sh...

18 Des 202537min

Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

Improve Energy & Longevity by Optimizing Mitochondria | Dr. Martin Picard

Dr. Martin Picard, PhD, is a professor of behavioral medicine at Columbia University and an expert on how our behaviors and psychology shape cellular energy production and rates of aging. He explains ...

15 Des 20253h 17min

Essentials: How to Build, Maintain & Repair Gut Health | Dr. Justin Sonnenburg

Essentials: How to Build, Maintain & Repair Gut Health | Dr. Justin Sonnenburg

In this Huberman Lab Essentials episode, my guest is Dr. Justin Sonnenburg, PhD, a professor of microbiology and immunology at Stanford University. We discuss how microbes in our gut impact our menta...

11 Des 202539min

Master the Creative Process | Twyla Tharp

Master the Creative Process | Twyla Tharp

Twyla Tharp is a world-renowned dancer, choreographer and expert on the creative process. She explains how to achieve creative success by keeping a highly disciplined routine that ultimately allows yo...

8 Des 20252h 30min

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