Essentials: Understanding & Treating Addiction | Dr. Anna Lembke
Huberman Lab26 Jun 2025

Essentials: Understanding & Treating Addiction | Dr. Anna Lembke

In this Huberman Lab Essentials episode, my guest is Dr. Anna Lembke, MD, Chief of the Stanford Addiction Medicine Dual Diagnosis Clinic at Stanford University School of Medicine. We discuss how dopamine drives reward, motivation and addictive behaviors. Dr. Lembke explains the concept of the pleasure-pain balance of dopamine and how this cycle plays a key role in the development and persistence of addiction. We also discuss some of the challenges of addiction recovery, including withdrawal, relapses and the potential benefits of psychedelic-assisted therapy. Read the episode show notes at hubermanlab.com. Thank you to our sponsors AG1: https://drinkag1.com/huberman Wealthfront**: https://wealthfront.com/huberman BetterHelp: https://betterhelp.com/huberman **This experience may not be representative of the experience of other clients of Wealthfront, and there is no guarantee that all clients will have similar experiences. Cash Account is offered by Wealthfront Brokerage LLC, Member FINRA/SIPC. The Annual Percentage Yield (“APY”) on cash deposits as of December 27,‬ 2024, is representative, subject to change, and requires no minimum. Funds in the Cash Account are swept to partner banks where they earn the variable‭ APY. Promo terms and FDIC coverage conditions apply. Same-day withdrawal or instant payment transfers may be limited by destination institutions, daily transaction caps, and by participating entities such as Wells Fargo, the RTP® Network, and FedNow® Service. New Cash Account deposits are subject to a 2-4 day holding period before becoming available for transfer. Timestamps 00:00:00 Anna Lembke 00:00:15 Dopamine, Reward & Movement 00:01:54 Baseline Dopamine; Genetics, Temperament & Addiction 00:05:24 Addiction, Modern Life & Boredom 00:07:18 Sponsor: AG1 00:08:55 Pleasure-Pain Balance, Dopamine, Addiction 00:14:17 Resetting Dopamine, Substance or Behavior Recovery, Tool: 30-Day Abstinence 00:16:04 Relapse, Addiction, Reflexive Behavior, Empathy 00:20:17 Triggers, Relapse, Dopamine 00:23:15 Sponsor: Wealthfront & BetterHelp 00:26:04 Shame, Truth Telling & Recovery 00:28:26 Addiction, Psychedelic-Assisted Therapy, Psilocybin, MDMA 00:33:29 Social Media & Addiction, Tool: Intentionality Disclaimer & Disclosures Learn more about your ad choices. Visit megaphone.fm/adchoices

Episoder(376)

Essentials: Erasing Fears & Traumas Using Modern Neuroscience

Essentials: Erasing Fears & Traumas Using Modern Neuroscience

In this Huberman Lab Essentials episode, I explore the neuroscience of fear and trauma and how to effectively process and eliminate traumatic responses. I explain why successful fear treatment requir...

6 Nov 202540min

Using Existing Drugs in New Ways to Treat & Cure Diseases of Brain & Body | Dr. David Fajgenbaum

Using Existing Drugs in New Ways to Treat & Cure Diseases of Brain & Body | Dr. David Fajgenbaum

My guest is Dr. David Fajgenbaum, MD, professor of translational medicine and human genetics at the University of Pennsylvania. He explains how, unbeknownst to most doctors, many approved medications ...

3 Nov 20251h 59min

Essentials: The Biology of Slowing & Reversing Aging | Dr. David Sinclair

Essentials: The Biology of Slowing & Reversing Aging | Dr. David Sinclair

In this Huberman Lab Essentials episode, my guest is Dr. David Sinclair, PhD, a professor of genetics at Harvard Medical School and a leading expert on the biology of aging. We discuss the cellular a...

30 Okt 202539min

Improve Your Lymphatic System for Overall Health & Appearance

Improve Your Lymphatic System for Overall Health & Appearance

Here I explain the lymphatic system, a crucial bodily network for overall health and appearance. I explain how the lymphatic system works to remove cellular waste and fluid from your organs and combat...

27 Okt 20251h 40min

Essentials: The Science of Gratitude & How to Build a Gratitude Practice

Essentials: The Science of Gratitude & How to Build a Gratitude Practice

In this Huberman Lab Essentials episode, I explore the science of gratitude and how to develop an effective, research-supported gratitude practice. I explain why common gratitude practices (like simp...

23 Okt 202539min

How to Overcome Inner Resistance | Steven Pressfield

How to Overcome Inner Resistance | Steven Pressfield

My guest is Steven Pressfield, author of The War of Art and expert in how to overcome the inner force of "resistance"—the self-sabotaging tendency to procrastinate on your life's most important work t...

20 Okt 20252h 15min

Essentials: How Your Brain Functions & Interprets the World | Dr. David Berson

Essentials: How Your Brain Functions & Interprets the World | Dr. David Berson

In this Huberman Lab Essentials episode, my guest is Dr. David Berson, PhD, a professor of neuroscience at Brown University and an expert on the visual system and circadian biology. We explore how th...

16 Okt 202540min

Protect & Improve Your Hearing & Brain Health | Dr. Konstantina Stankovic

Protect & Improve Your Hearing & Brain Health | Dr. Konstantina Stankovic

My guest is Konstantina Stankovic, MD, PhD, Professor and Chair of Otolaryngology at Stanford School of Medicine. She explains how hearing works and why hearing loss—affecting over 1.5 billion people—...

13 Okt 20252h 27min

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