Perimenopause Simplified23 Jul 2025

72. When Should You Start HRT? The Truth for Women in Their 40s

Confused about when to start hormone replacement therapy? You're not alone. In this episode of Perimenopause Simplified, we're cutting through the mixed messages and breaking down when to consider starting HRT, what symptoms to look out for, and how to know if it's the right move for you.

If you're in your 40s and feeling dismissed, overwhelmed, or unsure where to begin…this one's for you.

We cover:

Why hormone replacement therapy (HRT) is so confusing and what's changed since the 2002 WHI study
The difference between perimenopause and menopause & why that matters for HRT timing
Common early symptoms that may signal hormone shifts (and which hormone to start with first)
When estrogen might be added - it's earlier than you think
The risks of waiting too long to start HRT
Why and when I started HRT myself

Sources:

Hormone Therapy & Cardiovascular Disease: The Role of Timing

Hormone Therapy & Cognition

Prevention of Osteoporosis

NAMS Hormone Therapy Position

To learn about hormone therapy, grab Claudia's brand new, FREE resource: 3-Day HRT Crash Course.

In just 3 quick emails, you'll learn:

📌 What HRT is + how it works to improve symptoms
📌 The different types + how to choose for you
📌 Common mistakes (and how to avoid them)

To connect with Claudia Petrilli:

FREE GIFT: Peri-What?! The Must-Have Guide for Women 40+ Navigating Hormone Changes

FREE GIFT: Perimenopause Daily Checklist

WORK WITH US: The Perimenopause Method

BOOK A CLARITY SESSION: Perimenopause Clarity Session

HRT COURSE: Perimenopause HRT Roadmap

QUESTIONS? EMAIL: claudia@claudiapetrilli.com

Love the show? Please subscribe, leave a 5-star rating, review, and share, so that other women can find this podcast for guidance and support through their perimenopause journey!

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Episoder(122)

121. Not Sure What Age to Start HRT? This Will Help You Decide

2 Sep 9min

120. Blood Sugar After 40: Please Stop Fearing Carbs

Blood sugar and carbohydrates can feel incredibly confusing—especially in midlife, when changes in estrogen, muscle mass, sleep, stress, and body composition can affect metabolic health. In this episo...

26 Aug 16min

119. Walking: The Free Health Habit That Actually Matters After 40

Walking is one of the simplest—and most underrated—ways to support your health after 40. In this episode, we're talking about how daily walking can benefit cardiovascular health, metabolism, stress, s...

19 Aug 11min

118. What I Track as a Women's Health Coach Over 40: What Actually Matters

Are you tracking the right things for your health or just the things that create more stress? In this episode, I'm sharing exactly what I track as a women's health coach over 40, what I intentionally ...

12 Aug 12min

117. Why Following the Wrong Advice Keeps Women Stuck in Perimenopause

Between supplements, protocols, and influencers all claiming to have "the answer," it's easy to end up more overwhelmed than when you started — chasing what worked for someone else instead of what you...

5 Aug 9min

116. Protein After 40: How Much Do You Really Need & Are You Forgetting Carbs

Protein has become one of the biggest nutrition buzzwords, but are women over 40 focusing so much on protein that they're forgetting about carbs and fiber? In this episode, I'm breaking down how much ...

1 Jul 11min

115. Why You're Gaining Weight After 40 (Even Though You're Eating Healthy)

Frustrated because you're eating healthy, exercising, and still gaining weight after 40? Many women in perimenopause feel like their body suddenly stopped responding to the things that used to work. I...

24 Jun 14min

114. Why Your Workouts Aren't Working After 40

Working out but not seeing results after 40? Feeling frustrated that your body seems to be changing despite eating "healthy" and exercising? In this episode, I'm breaking down the biggest reasons your...

17 Jun 11min