PHARMACOGENETICS: WHY DRUG RESPONSES DIFFER IN A POPULATION OF PEOPLE │ EP56
Atomic Anesthesia13 Okt 2025

PHARMACOGENETICS: WHY DRUG RESPONSES DIFFER IN A POPULATION OF PEOPLE │ EP56

This is a joint episode recorded with Dr. Chloe Gomez of the My Favorite Learner podcast. This episode explores the foundational concepts of pharmacogenetics and its impact on drug responses during anesthesia, highlighting how genetic, genomic, and epigenetic variations shape individual reactions to commonly used medications in perioperative care. Designed for nurse anesthesia residents, the show walks through the scenarios of variable drug response, the roles of metabolizing enzymes, transport molecules, and molecular targets, as well as the influence of environmental factors and polymorphisms such as single-nucleotide variants and ethnic differences in metabolism. Key topics include disease-specific considerations like G6PD deficiency, acute intermittent porphyria, long QT syndrome, Brugada syndrome, atypical pseudocholinesterase, and malignant hyperthermia, with a focus on clinical implications for personalized medicine, precision dosing, and ethical issues surrounding genetic testing, privacy, and patient equity. Practical advice covers vigilant monitoring, individualized dosing, preoperative assessment for genetic risk, and strategies for documenting and communicating findings for safer anesthesia practice.

💜 LIVE WEBINAR: Save your seat on our monthly, free webinars. Replays are sent to your inbox and you get access to all of our previous webinars.

[WEBINAR SIGN UP]

💜 FREE DOWNLOADS: Grab your copy of customized study plans & worksheets.

[SEE/NCE STUDY PLAN]

[RN ICU DRUG CHART]

💜 CONNECT: 📥 Email questions, comments or topic suggestions to Dr. Temmermand at hello@atomicanesthesia.com, follow us on social media, and sign up for our launch newsletter ⬇️

[NEWSLETTER SIGN-UP]

[INSTAGRAM] [TIKTOK] [YOUTUBE]

Episoder(78)

WHY YOUR "STABLE" CIRRHOSIS PATIENT CAN CRASH ON INDUCTION │ EP78

WHY YOUR "STABLE" CIRRHOSIS PATIENT CAN CRASH ON INDUCTION │ EP78

Welcome to the Atomic Anesthesia podcast hosted by CRNA professor Dr. Rhea Temmermand and Co-Founder Sachi Lord. On this show, you'll hear clear, clinically grounded discussions designed for nurse ane...

22 Jan 20min

HOW TO [NOT] KILL YOUR AORTIC STENOSIS PATIENT │ EP77

HOW TO [NOT] KILL YOUR AORTIC STENOSIS PATIENT │ EP77

Welcome to the Atomic Anesthesia podcast hosted by CRNA professor Dr. Rhea Temmermand and Co-Founder Sachi Lord. On this show, you'll hear clear, clinically grounded discussions designed for nurse ane...

19 Jan 27min

CRASH, CODE OR CRUISE: IV ANESTHETIC CHOICES THAT CHANGE OUTCOMES [LIVE WEBINAR REPLAY] │ EP76

CRASH, CODE OR CRUISE: IV ANESTHETIC CHOICES THAT CHANGE OUTCOMES [LIVE WEBINAR REPLAY] │ EP76

Welcome to the Atomic Anesthesia podcast hosted by CRNA professor Dr. Rhea Temmermand and Co-Founder Sachi Lord. On this show, you'll hear clear, clinically grounded discussions designed for nurse ane...

15 Jan 1h 22min

DOES ANESTHESIA HARM THE BRAIN? A HARD LOOK AT THE DATA │ EP75

DOES ANESTHESIA HARM THE BRAIN? A HARD LOOK AT THE DATA │ EP75

Welcome to the Atomic Anesthesia podcast hosted by CRNA professor Dr. Rhea Temmermand and Co-Founder Sachi Lord. On this show, you'll hear clear, clinically grounded discussions designed for nurse ane...

13 Jan 21min

PROPOFOL REPLACEMENT? CIPEPOFOL AND THE FUTURE OF HIGH-RISK CARDIAC INDUCTION │ EP74

PROPOFOL REPLACEMENT? CIPEPOFOL AND THE FUTURE OF HIGH-RISK CARDIAC INDUCTION │ EP74

Welcome to the Atomic Anesthesia podcast hosted by CRNA professor Dr. Rhea Temmermand and Co-Founder Sachi Lord. On this show, you'll hear clear, clinically grounded discussions designed for nurse ane...

9 Jan 14min

ANESTHESIA MACHINE CHECK: A STEP-BY-STEP WALKTHROUGH OF YOUR WORKSTATION │ EP73

ANESTHESIA MACHINE CHECK: A STEP-BY-STEP WALKTHROUGH OF YOUR WORKSTATION │ EP73

Welcome to the Atomic Anesthesia podcast hosted by CRNA professor Dr. Rhea Temmermand and Co-Founder Sachi Lord. On this show, you'll hear clear, clinically grounded discussions designed for nurse ane...

5 Jan 17min

NEW YEAR, NEW PROVIDER: ANESTHESIA RESOLUTIONS FOR 2026 │ EP72

NEW YEAR, NEW PROVIDER: ANESTHESIA RESOLUTIONS FOR 2026 │ EP72

Welcome to the Atomic Anesthesia podcast hosted by CRNA professor Dr. Rhea Temmermand and Co-Founder Sachi Lord. On this show, you'll hear clear, clinically grounded discussions designed for nurse ane...

2 Jan 24min

KETAMINE UNLOCKED: MECHANISMS, DOSING & CLINICAL PEARLS │ EP71

KETAMINE UNLOCKED: MECHANISMS, DOSING & CLINICAL PEARLS │ EP71

Welcome to the Atomic Anesthesia podcast hosted by CRNA professor Dr. Rhea Temmermand and Co-Founder Sachi Lord. On this show, you'll hear clear, clinically grounded discussions designed for nurse ane...

22 Des 202523min

Populært innen Fakta

fastlegen
dine-penger-pengeradet
relasjonspodden-med-dora-thorhallsdottir-kjersti-idem
treningspodden
foreldreradet
jakt-og-fiskepodden
merry-quizmas
dopet
rss-sunn-okonomi
rss-strid-de-norske-borgerkrigene
hverdagspsyken
podme-bio-3
gravid-uke-for-uke
rss-kull
sovnlos
sinnsyn
tomprat-med-gunnar-tjomlid
dypdykk
rss-var-forste-kaffe
fryktlos