How to Build Muscle WITHOUT Lifting! Biohacker Longevity   : 1362

How to Build Muscle WITHOUT Lifting! Biohacker Longevity : 1362

Your workouts may be doing less than you think, and science now proves why. This episode reveals how to build muscle, improve metabolism, and extend longevity in a fraction of the time using blood flow restriction training and intermittent hypoxia. You’ll learn how to hack your mitochondria for faster recovery, stronger hormonal balance, and better brain performance without the burnout of high-intensity training.


Watch this episode on YouTube for the full video experience:

https://www.youtube.com/@DaveAspreyBPR


Host Dave Asprey talks with Dr. Sten Stray-Gundersen, PhD, CSCS, one of the world’s leading experts on blood flow restriction (BFR) training and metabolic physiology. With over a decade of research and teaching experience, Dr. Stray-Gundersen has explored how BFR and intermittent hypoxia can improve cardiovascular health, metabolism, and recovery. After earning his doctorate in Exercise Physiology from the University of Texas at Austin, he now serves as an Assistant Professor at the University of South Carolina, where he studies vascular adaptations, cognitive performance, and ergogenic aids. He’s also a B Strong master trainer, developing individualized BFR protocols for athletes, military professionals, and everyday people looking to optimize human performance.


Together, Dave and Sten uncover how BFR and oxygen cycling unlock powerful adaptations in the body’s vascular, metabolic, and hormonal systems. You’ll learn how strategic stress signals can trigger nitric oxide production, enhance glucose uptake, improve insulin sensitivity, and supercharge mitochondria for better energy and anti-aging benefits. They also explore how these methods can naturally boost testosterone, growth hormone, and even libido, all while protecting the nervous system and improving recovery.


This episode dives deep into biohacking, functional medicine, and smart exercise efficiency, from Zone 2 and REHIT training to nitric oxide signaling, fasting, nootropics, and precision supplementation. Whether your goal is longevity, strength, or sharper cognition, this conversation shows you how to get maximum results with minimal time using the principles of Smarter Not Harder.


You’ll Learn:

• How intermittent hypoxia works at the level of partial pressure and why altitude acclimation upgrades mitochondria and performance

• Why hypoxia and muscle contraction increase glucose uptake independent of insulin and improve insulin sensitivity

• How blood flow restriction (BFR) accelerates fatigue with light loads to drive hypertrophy, strength, and vascular adaptations

• How BFR and hypoxia influence testosterone, growth hormone, nitric oxide, and libido through short, targeted stress

• The roles of ENOS, INOS, and NNOS in nitric oxide signaling and what that means for circulation and brain perfusion

• Who benefits most from BFR, including athletes, rehab patients, and older adults who cannot lift heavy

• Why BFR produces systemic and “proximal” gains, including carryover to glutes and upper body during lower limb training

• How to stack BFR with Zone 2, REHIT, and vibration plates for VO2 max, muscle, and time efficiency


Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.


New episodes are released every Tuesday, Thursday, Friday, and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.


Keywords: Sten Stray-Gundersen, blood flow restriction training, B Strong, intermittent hypoxia, mitochondrial function, nitric oxide production, VO2 max, metabolic efficiency, vascular health, testosterone boost, growth hormone release, anti-aging performance, exercise recovery, glucose metabolism, functional medicine, biohacking fitness, REHIT training, Zone 2 optimization, strength and longevity, human performance science


Thank you to our sponsors!

-KILLSwitch | If you’re ready for the best sleep of your life, order now at https://www.switchsupplements.com/ and use code DAVE for 20% off.

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-ARMRA | Go to https://tryarmra.com/ and use the code DAVE to get 15% off your first order.


Resources:

• Use code DAVE10 to get a discount on a BFR band today: https://shopify.bstrong.training/products/b-strong-training-system?ref=dave%2F

• Dive deeper in Sten’s work at: https://bstrong.training/

• Danger Coffee: https://dangercoffee.com/discount/dave15

• My Daily Supplements: SuppGrade Labs (15% Off)

• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)

• Dave Asprey’s BEYOND Conference: https://beyondconference.com

• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated

• Upgrade Collective: https://www.ourupgradecollective.com

• Upgrade Labs: https://upgradelabs.com

• 40 Years of Zen: https://40yearsofzen.com


Timestamps:

0:00 - Trailer

1:25 - Guest Intro

5:40 - Intermittent Hypoxia & Altitude Acclimation

12:11 - Introduction to Blood Flow Restriction (BFR)

22:53 - Systemic Benefits & Who Can Use BFR

30:23 - BFR Effects on Hormones & Libido

40:37 - Nitric Oxide & Vascular Health

48:15 - Zone 2 Training with BFR

54:00 - Advanced Protocols: Stacking BFR

59:15 - Cognitive Enhancement & Wrap-Up

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Episoder(1420)

#60 Orgasmic Meditation & Hacking Your Sex Life, with Dr. Pooja Lakshmin

#60 Orgasmic Meditation & Hacking Your Sex Life, with Dr. Pooja Lakshmin

Discover orgasmic meditation (OMing) and the science behind it with Dr. Pooja Lakshmin, M.D., the CSO of OneTaste, and scientist at Rutgers University Newark Orgasm Laboratory. This episode discusses the relationship between orgasm and the nervous system, the importance of mindfulness, and how often men and women should orgasm for maximum performance in life. Be sure not to miss this stimulating episode! Formerly a psychiatrist at Stanford hospital, Pooja switched career paths after experimenting with OMing and researching the science behind it. She later moved across the country to New York City to study the neuroscience involved in OMing through fMRI imaging and clinical studies. Currently, Pooja continues to conduct OMing studies, while also venturing into further researching the male orgasm. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

12 Sep 201346min

#59 Hacking Productivity, Forming Habits & 'Lift' iPhone App, With Tony Stubblebine

#59 Hacking Productivity, Forming Habits & 'Lift' iPhone App, With Tony Stubblebine

Learn how to unlock your Bulletproof potential from the CEO of the habit-building app, Lift. Tony Stubblebine shares his take on what habits are good to form, and how to develop and sustain those habits by creating a supportive lifestyle. Tony and I also dug deep into the performance and emotional aspects of being a CEO. If you are a productivity hack or a high performing businessperson, than you do not want to miss this episode! Tony Stubblebine co-founded Lift based on the idea that positive reinforcement and community support could be deployed universally to help people achieve their goals. Prior to Lift, he was the founder and CEO of CrowdVine Event Social Networks, which builds simple and powerful software to help people connect and meet. He was also a part of the Wesabe launch team, Director of Engineering at Odeo.com and O'Reilly Media, and authored Regular Expression Pocket Reference. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

4 Sep 201354min

#58 Food Choices, Willpower & Sugar Cravings with Michael Fishman

#58 Food Choices, Willpower & Sugar Cravings with Michael Fishman

Take control of your food choices, understand your willpower, and combat sugar cravings by listening to this episode with expert health marketing advisor, Michael Fishman. You will hear how Michael radically changed his diet to be a healthier, more in control and happier version of himself, and how you can do that too. Michael Fishman is a leading advisor on marketing, positioning and strategy for health, wellness and personal development businesses and personalities such as Rodale's Prevention and Men's Health publishing brands, Dr. Andrew Weil, Dr. Mark Hyman, Dr. Christiane Northrup, Dr. Dean Ornish and many others. Michael is also a highly sought after speaker on how marketing language, customer care and work culture combine to take companies from merely good to the beloved best at what they do. He created the annual Consumer Health Summit, which is the preeminent invitational forum for CEOs, entrepreneurs and marketing leaders in health and wellness. He is also a co-founder of BehaviorCon, a conference on marketing and consumer psychology.  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

27 Aug 201347min

#57 Becoming Alpha, Dispelling Myths & Making Changes, with Adam Bornstein

#57 Becoming Alpha, Dispelling Myths & Making Changes, with Adam Bornstein

As a top health and fitness editor and best-selling author, Adam Bornstein came on the show to share what it means to be ‘Alpha’ and how being bulletproof is possible for everyone. In this episode, Adam and I discuss our shared egg obsession, whether cheat days are helpful or harmful, and how mental barriers keep you from achieving the best version of yourself. You will even get a glimpse into the workings of mainstream media, research, and health journalism. Adam Bornstein is a biohacking, solutions oriented machine! Adam has been named “one of the most influential people in health.” He’s a long time health and fitness writer and editor for magazines like Men’s Health and Livestrong, and best-selling author of four fitness books, including his most recent book “Man 2.0 Engineering the Alpha: A Real World Guide to an Unreal Life: Build More Muscle. Burn More Fat. Have More Sex” See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

20 Aug 201354min

#56 Biohacking Apocalypse Survival, Stress Inoculation & Shamans, with Sam Sheridan

#56 Biohacking Apocalypse Survival, Stress Inoculation & Shamans, with Sam Sheridan

In an apocalypse, how would you biohack your survival? This episode dives into answering this question and discusses all things stress-related. It was a blast having Sam Sheridan, best selling author of The Disaster Diaries: How I Learned to Stop Worrying and Love the Apocalypse, on the show to talk about a wide variety of topics ranging from endurance vs. interval training to Cooper’s Color Code and shamans. You’ll hear about the science and psychology of stress, the best way to handle stress, and how to better your chances of surviving an apocalypse. Sam Sheridan was an amateur MMA fighter, EMT, wild-land fire fighter, cowboy, sailor and worked construction at the South Pole. He is also the best selling author of A Fighters Heart: One Man’s Journey Through the World of Fighting, he Fighters Mind: Inside the Mental Game. During research for his latest book The Disaster Diaries: Sam immerses himself in the survivalist and dooms-day preparation subculture by:  Attending stunt driving school;  Learning the art of eskrima (Filipino knife fighting); Participating in Cody Lundin’s (Dual Survival on Discovery Channel) Aboriginal Living Skills School; Learning how to steal a car with ex-gang bangers in Los Angeles. A large portion of The Disaster Diaries explains the bio-chemical cocktail that our bodies produce during moments of intense stress (i.e.  an apocalypse.)  See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

13 Aug 201350min

#55 Fitness, Nutrition & Bulletproof Habits, with High Performance Health Coach, Yuri Elkaim

#55 Fitness, Nutrition & Bulletproof Habits, with High Performance Health Coach, Yuri Elkaim

From professional athlete to high performance health coach, Yuri Elkaim joins us today to talk about (almost) all things Bulletproof. In his goal to help 10,000,000 people become healthier, Yuri will share his take on raw food, the “fruit & veg” argument, exercise vs. rest, habits, and more! If you are an athlete (or biohacker) looking for 1 or 2 tips to take your performance to the next level, this is the show for you. Yuri Elkaim is a registered holistic nutritionist, fitness expert, and highly sought after high performance health coach. He’s also a former professional soccer player and served as the Head Strength & Conditioning and Nutrition Coach for men’s soccer at the University of Toronto for 7 seasons. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

9 Aug 201346min

#54 Neurofeedback Technology, Best Biohack Yet, with Dr. Valdeane Brown

#54 Neurofeedback Technology, Best Biohack Yet, with Dr. Valdeane Brown

This episode is all about the most effective biohack I’ve experience yet – NeurOptimal® brain training. Dr. Valdeane Brown, Founder of NeurOptimal, came on the show to explain how this technology takes your performance to uncharted levels! The NeurOptimal brain trainer is the most powerful and affordable neurofeedback technology available. You will get to hear about the EEG technology and how it transforms your brain, upgrade athletic performance, and even help with migraines, PTSD, and abusive relationships. Does this sound too good to be true? Listen for yourself… Dr. Valdeane W. Brown is an internationally recognized "trainer of neurofeedback trainers", who has taught and consulted widely on personal and organizational transformation. With a Ph.D. in Clinical Psychology and a background in math, physics, computer programming, philosophy, yoga, meditation and martial arts, Dr. Brown brings a presence and precision to his work. This is further informed by a profound sense of compassion, a facility with energy dynamics and a deep commitment to revealing the elegant simplicity inherent in learning and transformation. Developer of the Five Phase Model and co-creator with his wife Sue of the Period 3 Approach to Clinical Neurofeedback, Dr. Brown has realized his vision of a truly comprehensive training system in NeurOptimal. His vision in bringing NeurOptimal to the world is to make personal transformation effortless and available to all. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

6 Aug 20131h 1min

#53 Raw Vegan to Bulletproof Meat Eater - a beneficial transformation, with Kristen 'Raw' Suzanne

#53 Raw Vegan to Bulletproof Meat Eater - a beneficial transformation, with Kristen 'Raw' Suzanne

This episode brings to light an ex-vegan advocate’s journey to eating a mostly meat-embraced Bulletproof diet. Kristen ‘Raw’ Suzanne, author, popular blogger, and nutrition researcher, shared her former vegan assumptions, how easy or difficult it was to change, and the ethics of food. We also dove into a detailed conversations about liver meat, fertility issues on a vegan diet, how to stay Bulletproof when traveling with family, and how to nourish your kids the best way possible. In 2005, Kristen walked away from her corporate career in executive-level operations to focus on her true passion: healthy food. Already a vegan for two years, she turned her attention to the raw vegan cuisine and lifestyle, initially teaching classes and providing personal chef services, but as her online audience grew, she ultimately shifted to full-time blogging, recipe development, and eventually publishing 12 books on raw vegan diets. By 2012, concerns with her and her child's health forced her to reevaluate the nutritional claims made by advocates of raw and vegan diets. After Kristen introduced high quality animal products into her family's diet, she saw dramatic improvements almost immediately. Her family now eats a diet high in grass-fed beef and butter, bison, pastured eggs, and wild-caught seafood, while avoiding grains, gluten, and soy. While her personal transformation and conversion from vegan to omnivore has been controversial in the vegan and raw food community, Kristen has been on hiatus from blogging to spend time researching and fully exploring the nutritional and culinary aspects of eating in this new way for her family. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

1 Aug 201357min

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