Biohacking News Weekly Update : 1363

Biohacking News Weekly Update : 1363

This episode covers:


• Cocoa Extract Cuts Heart Deaths

A massive COSMOS trial found that older adults taking high flavanol cocoa extract daily saw a 27 percent reduction in cardiovascular deaths along with drops in inflammation markers like HSCRP. Women showed unique anti inflammatory cytokine shifts, pointing to a broader longevity effect. Dave explains why cocoa extract is becoming a foundational nutrient for vascular health rather than a dessert ingredient.

Source: https://www.sciencedaily.com/releases/2025/09/250926135957.htm


• AI Stethoscope for Home Diagnostics

Lapsi Health’s Keikku 2.0 just became the first FDA cleared AI powered digital stethoscope for both clinicians and home users. It records heart and lung sounds, analyzes them instantly, and flags early warning signs before symptoms appear. Dave breaks down why tools like this move you from reactive to predictive medicine and why they belong in every quantified self toolkit.

Source: https://www.prnewswire.com/news-releases/lapsi-health-unveils-keikku-2-0-worlds-first-fda-cleared-digital-stethoscope-with-integrated-ai-scribe-302585083.html?utm_source=chatgpt.com


• Beef Organ Supplements Surge

Beef organ supplements have exploded more than 8,000 percent this year, driven largely by women reporting improvements in energy, hormones, mood, and skin. Liver, kidney, and heart deliver vitamin A, heme iron, B12, copper, and choline that modern diets often lack. Dave covers sourcing concerns, purity standards, and why this shift reflects a move from fear based nutrition to evolutionary nutrition.

Source: https://www.verywellhealth.com/beef-organ-supplement-11710185?utm_source=chatgpt.com


• Spirulina for Collagen and DNA Protection

New research highlights spirulina’s ability to support collagen production, reduce oxidative stress, protect DNA, and improve glucose and lipid balance. It is becoming a staple of eco focused anti aging routines and is driving the viral green stacking trend with chlorella and chlorophyll. Dave explains why spirulina functions as a clean daily defense against oxidative stress.

Source: https://www.news-medical.net/news/20250707/Is-Spirulina-the-Next-Anti-Aging-Superfood.aspx


• Health Data Privacy Reform

A new Senate bill aims to extend HIPAA level protections to wearables, genomic tools, glucose monitors, and wellness apps. The goal is to give users control over who sees their biometrics, how they are stored, and whether they can be sold. Dave outlines why this matters for anyone using Oura, Whoop, CGMs, or genetic testing and why your biology should belong to you and not the cloud.

Source: https://natlawreview.com/article/federal-healthcare-update-november-7-2025


All source links provided for easy reference to the original reporting and research above.


This is essential listening for fans of biohacking, hacking human performance, functional medicine, and longevity who want actionable tools from Host Dave Asprey and a guest who embodies what it means to age with energy, clarity, and vitality.


Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade brings you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence, and conscious living.


New episodes are released every Tuesday, Thursday, Friday (audio-only), and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.


Keywords: cocoa extract, flavanols, heart health, nitric oxide pathways, COSMOS trial, AI stethoscope, digital diagnostics, Keikku device, predictive health tech, beef organ supplements, women’s hormonal health, nutrient dense foods, ancestral nutrition, spirulina benefits, collagen support, oxidative stress defense, green stacking, chlorella pairing, DNA protection, wearable privacy laws, HIPAA reform, biometric data rights, longevity news, biohacking updates


Thank you to our sponsors!


Resources:

• Subscribe to my weekly newsletter: https://substack.daveasprey.com/welcome

• Danger Coffee: https://dangercoffee.com/discount/dave15

• My Daily Supplements: SuppGrade Labs (15% Off)

• Favorite Blue Light Blocking Glasses: TrueDark (15% Off)

• Dave Asprey’s BEYOND Conference: https://beyondconference.com

• Dave Asprey’s New Book – Heavily Meditated: https://daveasprey.com/heavily-meditated

• Upgrade Collective: https://www.ourupgradecollective.com

• Upgrade Labs: https://upgradelabs.com

• 40 Years of Zen: https://40yearsofzen.com


Timestamps:

0:00 – Intro

0:19 – Cocoa Extract & Heart Health

1:52 – AI Digital Stethoscope

3:01 – Beef Organ Supplements

4:24 – Spirulina for Longevity

5:42 – Substack Announcement

6:53 – Health Data Privacy Reform

8:23 – Weekly Upgrade Protocol

9:46 – Outro

See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Episoder(1426)

Particle Size Matters: Masterclass in Using Silver for Biohacking - Steve Revelli : 1071

Particle Size Matters: Masterclass in Using Silver for Biohacking - Steve Revelli : 1071

Today, on The Human Upgrade, we talk to Steve Revelli about the long history and bright future of using silver nanoparticles as a biohacking silver bullet. Steve's background is in science and education, now serving as the QA Manager at American Biotech Labs, LLC, the brand which produces Silver Biotics—a long-time resident of my own medicine cabinet. The conversation covers the difference between pathogenic bacteria and probiotics, how silver under a concentration of 40 parts per million can target harmful bacteria while leaving healthy probiotics intact, the importance of nanoparticle size, antibiotic resistance, animal and agricultural applications, and so much more. You will learn how they use silver in the world of medicine (because they actually do and have for more than a hundred years) and how/when to use it yourself, whether topically, supplementally, or otherwise. This, my free-thinking friends, is a masterclass in using silver for biohacking.00:03:06 — Retelling the Long Story of Silver• Historical meaning of “born with a silver spoon”• Microbial elements of AG404–why it works• Chemistry deep dive, searching for missing electrons• Why doesn’t silver attack healthy cells?• Differences between prokaryotic cells• More is not always better00:11:22 — Delivery Systems to Improve Your Health• Importance of nanoparticle sizes in effective use• One warning: avoiding high salt• Using AG404 in nasal spray during air travel• Other off-label uses for Silver Biotics • Silver particles for immune support • Topical use for fighting infection • 70-year medical history of using silver for burns • Using a vertical sprayer for delivery• Code: DAVE for 30% off at silverbiotics.com00:27:09 — Cosmetic Benefits & Antibiotic Resistance• New formulations from Silver Biotics• Wrinkles, acne, cuts, scrapes, etc.• Facial serum vs. skin cream• Fighting antibiotic resistant bacteria • Pet care and successful applications in agriculture • Safety an ingestion cycles • Turning blue from silver toxicity • Relieving bacterial burden from your sinuses • Code: DAVE for 30% off at silverbiotics.comResources• Shop: Use code DAVE for 30% off at silverbiotics.com• Instagram: @silverbioticsThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

20 Jul 202343min

Let Them Eat Dirt: Biohacking Family Nutrition - Andrea Bemis : 1070

Let Them Eat Dirt: Biohacking Family Nutrition - Andrea Bemis : 1070

Today, we're delving deep into the importance of dirt, not just as soil beneath our feet, but as a key factor in regenerative agriculture and biohacking. Our guest, Andrea Bemis, is an expert in sustainable organic farming and a passionate advocate for nurturing healthy babies and children. Together, we explore the power of the family dinner and the significance of avoiding harmful chemicals and additives in the food we provide for our kids.Andrea Bemis, the brilliant mind behind the farm-to-table blog "Let Them Eat Dirt," joins us as our special guest. She has authored remarkable books, "Dishing Up the Dirt" and "Local Dirt," which provide invaluable insights into creating a healthy and nourishing food environment for children. Through our shared belief in empowering kids to make healthier choices, we aim to guide parents away from the junk and chemicals that can harm their children's well-being and towards more sustainable, locally sourced and economical options.Join us as we share our tips and tales from our own dinner tables, and our top strategies for nourishing your children with whole foods that taste good, too. Welcome, Andrea, to The Human Upgrade. 00:02:07 — Avoiding Processed Foods: Dangers of Heavy Metals & Artificial Sweeteners• How processed foods can change brain chemistry• The mistake parents of young children make when it comes to food• Tips for getting kids to eat diverse foods and flavors• Logistics of living on a farm• Benefits of buying from a CSA• The Baby Food Facts Report findings on sweeteners in baby food• Heavy metals in baby food00:21:01 — Healthy, Fast & Economical Recipes for Kids• Most economical ways to make healthier baby food at home • Recommended cooking oils for kids and why• Being mindful of how much kids are snacking• Not forcing your kid to eat when they’re not hungry• Andrea’s fast recipe ideas• How salt impacts babies’ digestive system• Read: Nourishing Traditions by Sally Fallon00:43:45 — Andrea’s Favorite Sweetener & Farm Life Insights• Andrea’s favorite sweetener for kids• Pros and cons of kale• Finding quality bacon • The most difficult crops to grow• Teaching your kids where food really comes from• Why small farms are so incredibly important & economicalResources• Website: dishingupthedirt.com• Instagram: @andreabemis• CSA: gotumbleweed.com• Read: letthemeatdirtkids.comThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

18 Jul 202355min

What Happens in the Gut, Starts in the Mouth – Naveen Jain : 1069

What Happens in the Gut, Starts in the Mouth – Naveen Jain : 1069

Today, a dear friend of the show and someone who's disrupted a huge part of the healthcare industry joins us for an informative chat on the critically important oral microbiome—and from a wider perspective—how and why the human body gets sick. Naveen Jain, founder of Viome—a data company that’s changing the world of health and wellness—goes deep on the latest in anti-aging, what's going on in your mouth and how that affects everything else in your body, the perils of mouthwash, the future of AI-powered analytics, business building with the right priorities in mind, and a whole lot more.And it all comes right back to the base definition, the core understanding, of what biohacking is—using the information and technology around us to live a longer and healthier life. Naveen’s company, Viome, is doing just that. You won’t want to miss this exclusive look into the future—for your own long-term health, or for that of society as a whole.00:01:44 — What Is It About the Human Body That Causes Us To Be Sick?• Fundamentally changing the way we look at the body • Dave’s homemade mouthwash and why he stopped using it • Power of individuality when it comes to health and longevity • Different impacts of foods on identical twins (Research)• What happens in the gut, starts in the mouth • The signals chewing your food sends to your body• Why a healthy oral microbiome means healthy sex 00:09:33 — Viome: Supercharging Human Data Analytics • Reading out the transcript from your body• Determining a diet-based source of bad breath • Viome’s biomarkers and aging score• Looking at RNA va. DNA• Shop viome.com and use code DAVE10 to save 10%• Pooling the data from 550,000 samples analyzed• Custom-made diet recommendations for your genetics• Affordability of Viome testing kits • Predicting mouth and throat cancer at a 95% rate • Personalized oral microbiome toothpaste gel 00:24:13 — Longevity & Lifespan: Our Health Is Our Wealth• Increasing our healthspan—adding truly viable years• Dave calls out the lifespan cowards• Choosing how and when we die: the ultimate goal for society • Naveen shares 5 ways to live a long and healthy life • Nutrition, getting the right fuel for the car• Stress management, escaping fight-or-flight mode• 40 Years of Zen neurofeedback therapy• Why you should quit your shitty stressful job• Smarter Not Harder by Dave Asprey• Prioritizing exercise, 30 minutes a day • Getting proper sleep, quality vs. quantity • Sleep with Dave: 14-day sleep challenge00:37:35 — A Message for the World’s Wantrepreneurs• Find a purpose and live 10 to 15 years longer• Focus on helping people live better—not making more money• Parasitic nature of modern commerce• Amazon’s quality spiral and the race to the bottom • Impacting the world in your uniquely powerful way• Our success will never be defined by how much money we madeResourcesInstagram: @viomeInstagram: @naveenjainceoViome: viome.com (Code DAVE10 to save 10%)Website: naveenjain.comThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

13 Jul 202345min

You Control Your Own Karma! – Sadhguru : 1068

You Control Your Own Karma! – Sadhguru : 1068

IN THIS EPISODE OF THE HUMAN UPGRADE™️... Sadhguru, a yogi, mystic, visionary and spiritual master who spreads wisdom around the world, clarifies the meaning of karma (no, it’s not a checklist of good and bad deeds) and explains how much you’re in charge of your own karma. His most recent book, “Karma: A Yogi’s Guide to Crafting Your Destiny,” breaks down the ways in which karma frames our lives.“It’s time to unpack the most overused, abused and yet indispensable world in the spiritual vocabulary of the world,” says Sadhguru in his book. “It is time to examine how karma is connected to some of the most vital areas of human inquiry: the meaning of life and above all, how to live it.”See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

11 Jul 202342min

Happiness Starts with Your Brain Type! – Dr. Daniel Amen : 1067

Happiness Starts with Your Brain Type! – Dr. Daniel Amen : 1067

IN THIS EPISODE OF THE HUMAN UPGRADE™...“Americans are the unhappiest they have been since the Great Depression,” says Dr. Daniel Amen. But he’s determined to change that. He’s a physician and double board-certified psychiatrist who looks at happiness as a brain function. After studying more than 200,000 brain scans of people from 155 countries, Dr. Daniel Amen discovered five primary brain types and seven neuroscience secrets that influence happiness.“I wanted to spend my time and energy and research on happiness because, ultimately... happiness is a moral obligation because of how you impact other people,” Dr. Amen says. “The big central point [is] the brain is the organ of happiness, and if your brain is not healthy, you are not likely to be happy.”What makes you happy? The answer lies in knowing your specific brain type and how it’s being influenced by seven specific chemicals.Happiness originates in distinct brain regions: pleasure in the orbitofrontal cortex; motivation and habit formation in the basal ganglia; and mood and cognitive flexibility in the brain stem.You may be one or a combination of these five primary brain types: (take this brain assessment to find out yours)Balanced: you have a very healthy brainSpontaneous: you have low dopaminePersistent: you’re often worried, rigid, and inflexibleSensitive: you need other people and isolation is hardCautious: your GABA levels are lowLearn more about brain types and what actually boosts your happiness according to neuroscience in Dr. Amen’s book, "You, Happier: The 7 Neuroscience Secrets of Feeling Good Based on Your Brain Type.”“Happiness comes from moving your life forward toward your life goals with meaning and purpose, based on your values, despite whatever obstacles are in your way,” Dr. Amen says. “A happy life doesn’t focus on the past with regret or look to the future with fear.” See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

6 Jul 20231h 21min

You’re Not Crazy, Toxic Mold Exposure Is Poisoning Your Brain - Brian Karr : 1066

You’re Not Crazy, Toxic Mold Exposure Is Poisoning Your Brain - Brian Karr : 1066

If you have all sorts of unexplained health problems in your home, where you work, or where you go to school, symptoms can be very different. One person's gaining fat, another person's always tired, other people have dark circles, emotional irregularity, sudden weight gain, onset of allergies that no one can explain, on and on.In the episode today, you learn the smarter, not harder, ways to deal with toxic mold exposure in your environment from one of the world’s leading experts on the matter. Our guest is Brian Karr. He's a second-generation indoor environmental consultant and he works with hypersensitive individuals with complex medical conditions. He's the co-founder of We Inspect, an environmental testing company which works to help people understand mold, mycotoxins, and even bacterial toxins that exist in your homes. He takes time to explain what's (usually) there, why it’s important—even down to the genetic level—and what it's doing to you.Go back to the definition of biohacking… The art and science of changing the environment around you and inside of you so that you have full control of your own biology. If your environment is moldy and has biotoxins, maybe you don't have control of your biology—the mold does.Brian's become a go-to guy for medical doctors across the country, helping more than 5,000 people as sensitive as I used to be to create healthier living environments. You're going to learn a lot in this episode, even if you're saying… Well, I don't have a mold problem. You'd be very surprised.00:17:00 — Meeting the Mold (and Brian) Head On• Dave’s younger years battling his own health • The xenoestrogen that took over his life• Brian Karr’s background and introduction• We Inspect environmental testing company • Moldy Movie: moldymovie.com• How Brian married into the business and fell in love • Building an infrastructure to serve the country• Betsy Maldonado’s story 00:15:02 — We Inspect: Spotlighting Innovation & Access • We Inspect’s process—what’s unique and special?• Most mold is hidden out of plain sight • Perils of dry mold: more mobile than wet, living mold• The importance of knowing what to look for• Prioritizing innovation and accessibility • Training program: Mold Finders Method • Mobile app: We Inspect Together• Pitfalls of other, commercially driven services 00:29:18 — Dealing With Mold in Our Day to Day Lives• Brian’s game plan for getting out of a moldy lease • Does spraying bleach work?• Why Dave avoids AirBnbs• Homebiotic: homebiotic.com• Balancing removal options • Three easy steps to take in your home• Understanding the Human Cloud Effect • Gaps in capability of air testing • Effectiveness of dust sampling • Find Out If Your Home Is Making You Sick• 100M structures in the US have meaningful mold problems00:50:04 — Looking Ahead At Life With Less Mold• 90% of structures are exposed to toxic mold• Danger Coffee: dangercoffee.com• What is truly pure?• Balance of bacteria vs. mold in caves • Added susceptibility of women and children• 40% of population impacted by mold exposure • Story time: Dave’s mold-triggered PANDASWE LOVE OUR SPONSORS! CHECK THEM OUT:• We Inspect environmental testing company • The Dust Test: thedusttest.com/dave• YesWeInspect.com/Dave• Moldfinders on Instagram• Brian Karr on LinkedIn• Moldfinders on Facebook• Moldy MovieThe Human Upgrade is produced by Crate Media.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

29 Jun 20231h 9min

Live From The 9th Annual Biohacking Conference: Biohacking the Red Planet with Vera Mulyani : 1065

Live From The 9th Annual Biohacking Conference: Biohacking the Red Planet with Vera Mulyani : 1065

In this special episode of The Human Upgrade LIVE from the 9th annual Biohacking Conference in Orlando Florida, Dave speaks Vera Mulyani, co-founder of Astrobiome and Mars City Design. Vera discusses the connection between biohacking and living on Mars and emphasizes the importance of designing the Martian environment to control human biology, taking into account mental health and architectural expertise. They also highlight challenges like toxic chemicals in spacecrafts and the need to biohack humans for space. Vera introduces Astrobiome, a microbiome product made from fermented bacteria, designed to optimize gut health in extreme conditions. Success stories demonstrate its effectiveness in improving health and performance. The podcast explores the intersection of biohacking, space exploration, and the significance of microbiome health in Mars-like environments.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

27 Jun 202323min

Live From The 9th Annual Biohacking Conference: Protein Panel with Max Lugavere & Dr. Amy Shah : 1064

Live From The 9th Annual Biohacking Conference: Protein Panel with Max Lugavere & Dr. Amy Shah : 1064

In this special episode recorded live from the 9th Annual Biohacking conference in Orlando, Dave dives into the vegan vs. animal protein debate with Max Lugavere and Dr. Amy Shah. They explore the reasons behind choosing a vegan lifestyle, including health, reducing animal suffering, and environmental concerns. Max defends animal protein, highlighting its efficiency and amino acid bioavailability, while Dr. Amy advocates for a balance between plant and animal protein, emphasizing the importance of plant fiber for gut health. They discuss studies linking meat consumption to cardiovascular disease and share their personal experiences, ultimately encouraging listeners to find their own balanced approach to protein. They also delve into topics such as protein intake, muscle building, longevity, fasting, circadian-style eating, and the impact of carbohydrates on the body. 9th Annual Biohacking Conference: You’ll learn from dozens of experts at an amazing event that’s designed to upgrade every area of your life. https://biohackingconference.comSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

22 Jun 202344min

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