95: Mitochondria transfer: biotech strategies and clinical hurdles
Kubat GB et al., Nature Communications - This Perspective surveys recent biotechnological advances that enhance mitochondria transfer and transplantation (MTT) — including surface functionalization, e...
3 Aug 202519min
94: Intraindividual epigenetic heterogeneity in advanced prostate cancer
Mizuno K et al., Nature Communications - Multi-omic profiling (DNA methylation, RNA-seq, H3K27ac and H3K27me3) of 98 metastatic CRPC samples from 35 patients reveals patient-specific epigenetic signat...
2 Aug 202520min
93: Bovine H5N1 Shows Neurovirulence in Mice
Tipih T et al., Nature Communications - Comparative mouse study finds a dairy-cow-derived H5N1 clade 2.3.4.4b (genotype B3.13) isolate is highly virulent, producing rapid respiratory failure, systemic...
1 Aug 202519min
92: Loss of CFHR5 Function Lowers AMD Risk
Nature Communications - A FinnGen-based genetic and functional study identifies CFHR5 loss-of-function variants as independently protective against age-related macular degeneration and links reduced F...
31 Jul 202516min
91: Plasma N‑Glycome, Liver Disease & Anti‑inflammatory Proteins
Sharapov S et al., Nature Communications - This episode examines a large multi-cohort GWAS of the human plasma N-glycome (N≈10,764) that maps genetic regulation of protein N‑glycosylation. The study d...
30 Jul 202517min
90: Sex, APOE-ε4 and TREM2: Who drives tau in medial temporal and neocortex?
Giorgio J et al., Nature Communications - A multi-cohort neuroimaging and genetics study (n=1,354) used PET and causal path modelling to test how sex, APOE-ε4 dosage and TREM2 rare variants influence ...
29 Jul 202515min
89: Genetics of Smell and Sex Differences
Förster F et al., Nature Communications - This GWAMA of up to 21,495 European-ancestry participants used the Sniffin' Sticks odour identification test to map genetic variants influencing identificatio...
28 Jul 202520min
88: Stable heritability of childhood Type 1 diabetes
Wei Y et al., Nature Communications - A Swedish nationwide register study of 2.93 million children born 1982–2010 found that the heritability of childhood-onset type 1 diabetes remained high (~0.83) a...
27 Jul 202518min
