Comparable roles for serotonin in rats and humans for computations underlying flexible decision-making
Serotonin is a critical chemical when it comes to a number of psychiatric conditions, such as OCD, where it seems to play a particular role in cognitive flexibility. That is, serotonin levels are rela...
4 Jan 20249min
Integrating public health and translational basic science to address challenges of xylazine adulteration of fentanyl
The drug naloxone, otherwise known as Narcan, is a critical tool in reversing fentanyl overdoses and reducing mortality. But now fentanyl is appearing on the streets adulterated with a drug called xyl...
16 Okt 20239min
The why, when, where, how, and so what of so-called rapidly acting antidepressants
Sanjay Mathew is a professor and vice chair for research at Baylor College of Medicine and director of the Mood and Anxiety Disorders Program. He’s one of the two authors of a recent review paper in t...
6 Sep 20238min
AI-based analysis of social media language predicts addiction treatment dropout at 90 days
In-person treatment for substance use disorders is an incredibly important tool, but there’s a high failure rate — more than 50 percent of people who enter drop out within the first month. There hasn’...
23 Jun 20239min
Oxytocin effects on amygdala reactivity to angry faces in males and females with ASPD
Antisocial personality disorder, or ASPD, is a difficult disorder to study. There have been studies on psychopathic individuals, and on youth with psychopathic traits, but most studies on ASPD to date...
21 Apr 20239min
To dismantle structural racism in science, scientists need to learn how it works
It’s clear there are diversity issues in science, both in terms of who does or doesn’t receive research grants, as well as who is or isn’t represented at the highest levels of scientific research. Whe...
22 Feb 20239min
Low doses of lysergic acid diethylamide (LSD) increase reward-related brain activity
Psychedelic drugs have received attention recently for their potential use as treatments for psychiatric disorders. Single, high doses of LSD have shown promise for treating depressive disorders. But ...
22 Des 20229min
Sex-dependent risk factors for PTSD: a prospective structural MRI study
After a traumatic event, women are more likely to be diagnosed with post-traumatic stress disorder, or PTSD. Research has been conducted on what might be causing this higher rate of diagnoses; for ins...
1 Nov 20229min
