10-Minute Biohacking News Update : 1367

10-Minute Biohacking News Update : 1367

This episode covers:


Nano CBD Pain Relief Without Cognitive Side Effects


A new nano-micelle formulation of CBD called CBD-IN delivers fast, non-addictive pain relief in mice without memory issues, motor impairment or the usual cannabinoid “fog.” Because it crosses the blood brain barrier and directly targets hyperactive pain circuits, it sidesteps many opioid-type drawbacks. Dave explains why precision-designed cannabinoids could reshape chronic pain treatment and longevity support.

Source: https://www.sciencedaily.com/releases/2025/11/251117095652.htm



Moderate Calorie Restriction Slows Biological Aging


A long-term trial from the National Institute on Aging found that cutting calories by about 12% over two years slowed the pace of aging — measured by methylation clocks and metabolic markers — in lean and mildly overweight adults alike. Dave breaks down why small, manageable dietary tweaks can deliver big longevity gains, without crash dieting or extreme fasting.

Source: https://www.nia.nih.gov/news/cutting-calories-may-slow-pace-aging-healthy-adults


FDA Approves AI-Guided Robotic Surgery Trials for Alzheimer’s


The U.S. Food and Drug Administration (FDA) has granted IDE approval for the first robotic microsurgical study targeting early stage Alzheimer’s disease using AI and deep imaging. The trial uses adaptive robotics to target deep brain lymphatic pathways, potentially clearing amyloid/tau deposits with surgical precision. Dave explains why this signals a new era in neurodegeneration – moving from drug-only to machine-assisted brain repair.

Source: https://www.mmimicro.com/ide-approval-for-first-robotic-microsurgery-alzheimers-study/


Antibiotic Reprograms Gut Bacteria to Produce Anti-Aging Molecules


Researchers demonstrated that the veterinary antibiotic cephaloridine can reprogram gut microbes to secrete colanic acid — a molecule linked to better mitochondrial health, reduced gut permeability and improved cholesterol/insulin balance in mice. Dave explores how this could evolve into a pipeline of engineered probiotics that act as internal “longevity factories.”

Source: https://newatlas.com/aging/antibiotic-longevity-microbiome/ (link remains unchanged)


Klotho: The Longevity Protein Nears Clinical Reality


The longevity protein Klotho, known for clearing toxic by-products, calming inflammation and protecting brain/organ networks, is now advancing toward human trials via injectables, oral formats and gene therapy. Dave explains why Klotho is shaping up as a foundational target for next-gen age-reversal strategies and stacking protocols.

Source: https://investingnews.com/longevity-focused-health-fueling-u-s-anti-aging-products-market-projected-to-reach-27-billion-by-2033/ (link remains unchanged)


All source links provided for easy reference to the original reporting and research above.


This episode is essential listening for fans of biohacking, human performance, functional medicine and longevity who want practical tools from Host ­Dave Asprey and the latest breakthroughs shaping the future of health.


Dave Asprey is a four-time New York Times bestselling author, founder of Bulletproof Coffee, and the father of biohacking. With over 1,000 interviews and 1 million monthly listeners, The Human Upgrade gives you the knowledge to take control of your biology, extend your longevity, and optimize every system in your body and mind. Each episode delivers cutting-edge insights in health, performance, neuroscience, supplements, nutrition, biohacking, emotional intelligence and conscious living.


New episodes are released every Tuesday, Thursday, Friday (audio only) and Sunday (BONUS). Dave asks the questions no one else will and gives you real tools to become stronger, smarter, and more resilient.


Keywords: nano CBD, CBD-IN, pain relief research, non opioid pain therapies, chronic pain and aging, caloric restriction aging, methylation clocks, metabolic resilience, AI robotics, Alzheimer’s microsurgery, neurotech advancement, microbiome engineering, colanic acid, longevity probiotics, mitochondrial support, Klotho protein, anti aging gene therapy, cellular rejuvenation, longevity news, biohacking updates


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Timestamps:

0:00 — Intro

0:19 — Story 1: Nano CBD for Pain Relief

1:53 — Story 2: Caloric Restriction and Aging

3:20 — Story 3: AI Robotic Surgery for Alzheimer’s

4:50 — Story 4: Microbiome Reprogramming

6:05 — Substack Announcement

7:04 — Story 5: Klotho Longevity Protein

8:39 — Weekly Homework

9:31 — Outro

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Avsnitt(1431)

Sid Baker: Beetlejuice! Beetlejuice! Beetle Larvae? - #311

Sid Baker: Beetlejuice! Beetlejuice! Beetle Larvae? - #311

Sidney Baker is a doctor, author and lecturer who helped in founding functional medicine and Autism organizations and developed patents and inventions within the medical information technology field. Dr. Baker raises HDCs and probiotics including grain beetles for consumption by patients with autoimmune problems. He has a longstanding devotion to the idea that the patient, not the diagnosis, is the target of treatment. On today's episode of Bulletproof Radio, Dave and Sid talk about Autism causation and treatment, pediatrics, eating beetles and worms, autoimmunity, activated charcoal, C-Sections and more. Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

20 Maj 20161h 12min

Harsha Chigurupati: Liver-Lovin' Liquor - #310

Harsha Chigurupati: Liver-Lovin' Liquor - #310

Harsha Chigurupati is the founder of Chigurupati Technologies, a research-focused company with the mission "to aid in the evolution of mankind." Chigurupati is the inventor of NTX Technology, a technology that gave rise to a new category of alcoholic beverages called Functional Spirits, which maintains the positive experiences associated with alcohol consumption while reducing alcohol-induced stress on the body. Chigurupati and his partners recently petitioned the TTF to allow them to use accurate, scientifically-backed health claims on their labels. On today's episode of Bulletproof Radio, Dave and Harsha talk about NTX's manufacturing process, nutrition labels, the Functional Spirit, alcohol regulations, hangover solutions and more. Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

17 Maj 20161h 3min

Vishen Lakhiani: 10 Laws & Four-Letter Words - #309

Vishen Lakhiani: 10 Laws & Four-Letter Words - #309

Vishen Lakhiani is a meditation expert, philanthropist and founder and CEO of Mindvalley. Mindvalley is a premiere edu-tech company specializing in promoting improvements with personal well-being, mindfulness, relationships, fitness and entrepreneurship. His new book, The Code of the Extraordinary Mind, discusses ways to optimize the brain for prime happiness and performance. On today's episode of Bulletproof Radio, Dave and Vishen talk about luck, being "unfuckwithable," developing language habits, the indoctrination of beliefs, goal-setting and more. Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

13 Maj 201657min

Dan Kittredge - Meanwhile, Back at the Ranch

Dan Kittredge - Meanwhile, Back at the Ranch

Dan Kittredge is a life-long organic farmer as well as founder and executive director of the Bionutrient Food Association. The BFA advocates for the shift from the century-long paradigm of factory farming to one in which quality food is profitable, ecologically sustainable, tastier and equally available to all. On today's episode of Bulletproof Radio, Dave and Dan talk about organic farming, finding quality vegetables, supplementing your diet, nutrient-rich foods and a simple diet. Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

10 Maj 20161h

James Swanwick - Be Wiser Without Budweiser : 307

James Swanwick - Be Wiser Without Budweiser : 307

James Swanwick is an Australian-American entrepreneur, former SportsCenter anchor on ESPN and host of The James Swanwick Show podcast. He is the creator of the 30 Day No Alcohol Challenge, which helps you reduce or quit alcohol. On today's episode of Bulletproof Radio, James and Dave talk about the social pressure to drink alcohol and how to conquer it, the marketing tactics of the alcohol industry, considering light as a drug and more. Enjoy the show!See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

6 Maj 20161h 2min

Tony Robbins & Peter Diamandis - Special Podcast, Live From The Genius Network

Tony Robbins & Peter Diamandis - Special Podcast, Live From The Genius Network

This special episode of Bulletproof Radio showcases an exclusive conversation between Tony Robbins, Peter Diamandis and Joe Polish through Joe's Genius Network. Tony Robbins is a world-famous motivational speaker, personal finance instructor and self-help author who partnered with Feeding America to provide 100 million meals to families in need. Peter Diamandis is an engineer, physician and entrepreneur best known for being the founder and chairman of the X Prize Foundation. The X Prize is a competition in which thinkers from all walks of life work on innovations to improve the world, and it has been integral to the development of commercial space travel. During this episode of Bulletproof Radio, Peter and Tony talk about solving humanity's challenges, stress and adversity, achieving the impossible, the power of live-work integration and more! Enjoy the show. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

3 Maj 201655min

Jonny Bowden - The Proof is in the Pork #305

Jonny Bowden - The Proof is in the Pork #305

Jonny Bowden is a nationally known board-certified nutritionist and expert on diet and weight loss. He has appeared on the Dr. Oz Show, Fox News, CNN, MSNBC, ABC, NBC and CBS and has contributed to articles in The New York Times, Forbes, The Daily Beast, The Huffington Post, Vanity Fair Online, Men's Heath, Prevention and dozens of other print and online publications. He is the best-selling author of 15 books and his latest is Smart Fat: Eat More Fat, Lose More Weight, Get Healthy Now! On today's episode of Bulletproof Radio, Dave and Jonny talk about the low-fat diet myth, evidence-based diet claims, contaminated foods, plant-based fats, recommended Omega ratios and more. Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

29 Apr 201651min

Gerald Pollack - It's Not Liquid, It's Water: #304

Gerald Pollack - It's Not Liquid, It's Water: #304

Gerald Pollack received his PhD in biomedical engineering from the University of Pennsylvania in 1968 and continued his research thereafter as a member of the University of Washington faculty. He is a professor of Bioengineering and is also the Founding Editor-in-Chief of the journal WATER, convener of the Annual Conference on the Physics, Chemistry and Biology of Water and Executive Director of the Institute for Venture Science. On today's episode of Bulletproof Radio, Dr. Pollack and Dave talk about landmark discoveries in the sciences of water, mineral water, ozone therapy, infrared light, the Hunza people, hydration and more. Enjoy the show! See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

26 Apr 20161h 27min

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