368. FROM BLACKOUT DRINKER TO PEPTIDE COACH Addiction, Dopamine & Rewiring the Brain with Samantha Lander

WHY DO WE DRINK?

Why do we drink? And when does alcohol move from pleasure and social connection to becoming a way of regulating stress, anxiety or difficult emotions?

This week we meet Samantha Lander, who openly shares her powerful story of ADHD, addiction, recovery and relapse. Her journey included meth, Molly and other drugs, and later becoming what she describes as a blackout drinker.

Today, Samantha works in functional health and is a well-known peptide coach, with a particular interest in how we can support the brain and body during recovery.

We talk about dopamine, GABA, sleep, stress and “hangxiety,” the connection between ADHD and alcohol, and what can happen when we remove the substance we've been using to regulate ourselves.

And of course, we dive into peptides. Samantha teaches about peptides and biological recovery, so we ask: Could peptides have a future role in addiction and recovery? Which mechanisms are particularly interesting, from inflammation and metabolism to the gut-brain axis and stress response and where is the science today?

Samantha also shares her fascinating personal experience with the pepitde Klotho, an emerging longevity-related protein being explored in peptide research, and the remarkable results she says she has experienced herself.

She also shares her thoughts on retatrutide versus tirzepatide, and why, in her experience, she currently prefers tirzepatide when it comes to managing cravings and food noise.

And she revisits AOD-9604, an older peptide developed from a fragment of human growth hormone, and shares her perspective on why it remains interesting in conversations around fat metabolism and metabolic health.

We also explore the growing “California sober” movement replacing alcohol with cannabis or other substances and ask whether this is genuine harm reduction or simply another way of regulating the nervous system.

If we take away the alcohol, what can give us calm, reward and dopamine instead?

An open conversation about alcohol, addiction, recovery, peptides and finding new ways to regulate, heal and feel good again.

Du finner Samatha her: @seefitliving

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