Episode 311: 310. METHODS MONDAY!! What is a Non-Inferiority Trial

Episode 311: 310. METHODS MONDAY!! What is a Non-Inferiority Trial

A noninferiority trial is a type of randomized trial that aims to establish if treatmenet X effectiveness is not substantially less than the existing standard. Unlike superiority trials that are designed to show that one treatment is better than another, a non-inferiority trial is designed to show that a new treatment is ‘not unacceptably worse’ than the current standard therapy. You want to see if the drug you are testing is good enough compared to the standard.

Say you wanted tacos from your favorite place across town cause they have the best tacos but there is another taco place that is across the street the tacos are not as good but they are pretty close and it is a 20 second walk not a 20 minute drive. You might quickly in your mind calculate the trade off and say well the place across the street is noninferior.

Jaksot(385)

52. Should You Question Santa's Health?

52. Should You Question Santa's Health?

Is christmas in danger? What about Santa's Health? Is is the season of holiday joy and cheer and this podcast should have you tapping your toes while Andrew belly flops into an extensive literature di...

20 Joulu 20160s

51. An Irresistible Podcast on Antibiotic Resistance

51. An Irresistible Podcast on Antibiotic Resistance

In this episode Andrew is back on his motorcycle (riding solo). He covers antibiotics resistance and are people not taking a full course of antibiotics really the problem? This episode is full of soun...

17 Marras 201617min

46. Medical Myths for April Fools

46. Medical Myths for April Fools

It is April Fools day and it only seemed right to do a little medical myth busting. In this episode and gulps down the evidence around how much water we should drink. He find out that more money does ...

1 Huhti 201614min

43. Working Out Evidence on Treatment for Depression

43. Working Out Evidence on Treatment for Depression

This episode Andrew is working out the evidence on depression. He addresses the 500lb elephant around the future of Questioning Medicine, but luckily he doesn't try to lift it. He also makes everyone ...

22 Tammi 201621min

41. Getting Maddrey About Alcoholic Hepatitis

41. Getting Maddrey About Alcoholic Hepatitis

Andrew is by himself and trying to struggle through the harsh Florida winter. The question today is should steroids, more specifically prednisolone, be given to those with alcoholic hepatitis? A quick...

30 Marras 201517min

36. Granulocyte Colony Stimulating Factor -- Is It Worth a Stimulating Conversation?

36. Granulocyte Colony Stimulating Factor -- Is It Worth a Stimulating Conversation?

Andrew is back to being by himself. When you get out questioned in questioning medicine its time for a podcast update. This episode briefly touches on the granulocyte colony stimulating factor and is ...

14 Elo 201513min

28. HPV: A Non-Contact Encounter

28. HPV: A Non-Contact Encounter

Boy bands from the 80's might have helped you survive childhood, but now they escort in a new era of non-contact HPV testing. Andrew discusses the potential option for women to do their own testing pr...

4 Huhti 201527min

27. Cervical Cancer Screening and HPV part 2

27. Cervical Cancer Screening and HPV part 2

Andrew and Joe discuss the new guidelines or guidance on using the pap smear with HPV for cervical cancer screening in low risk women. Andrew learns 80's rock trivia and Joe gives level C- evidence. M...

20 Maalis 201527min

Suosittua kategoriassa Terveys ja hyvinvointi

unicast
psykopodiaa-podcast
voi-hyvin-meditaatiot-2
tiedenaiset-podcast
rss-pitaisko-erota
vakeva-elama-viisaampi-mieli-vahvempi-keho
meditaatiot-suomeksi
rss-narsisti
puhu-muru
junnut-pelissa
terapiassa
aamukahvilla
mielen-puolikkaat
rss-mighty-finland-podcast
rss-kuumilla-aalloilla
paritellen
rss-pt-paahtio
rss-adama-mindful-hetki
rss-en-saa-unta
rss-vapaudu-voimaasi