198 | Nick Lane on Powering Biology

The origin of life here on Earth was an important and fascinating event, but it was also a long time ago and hasn't left many pieces of direct evidence concerning what actually happened. One set of clues we have comes from processes in current living organisms, especially those processes that seem extremely common. The Krebs cycle, the sequence of reactions that functions as a pathway for energy distribution in aerobic organisms, is such an example. I talk with biochemist about the importance of the Krebs cycle to contemporary biology, as well as its possible significance in understanding the origin of life.

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Nick Lane received his PhD from the Royal Free Hospital Medical School. He is currently a professor of Evolutionary Biochemistry at University College London. He was a founding member of the UCL Consortium for Mitochondrial Research, and is Co-Director of the UCL Centre for Life's Origin and Evolution. He was awarded the 2009 UCL Provost's Venture Research Prize, the 2011 BMC Research Award for Genetics, Genomics, Bioinformatics and Evolution, the 2015 Biochemical Society Award, and the 2016 Royal Society Michael Faraday Prize and Lecture. His new book is Transformer: The Deep Chemistry of Life and Death.


Jaksot(416)

339 | Ned Block on Whether Consciousness Requires Biology

339 | Ned Block on Whether Consciousness Requires Biology

It's become increasingly clear that the Turing Test -- determining whether human interlocutors can tell whether a conversation is being carried out by a human or a machine -- is not a good way to thin...

5 Tammi 1h 11min

Holiday Message 2025 | The Romance of the University

Holiday Message 2025 | The Romance of the University

Time for the holiday message! Rounding off the year with a brief and casual reflection on some issue that doesn't quite rise to the level of a full solo podcast. And hopefully something uplifting. Thi...

22 Joulu 202542min

AMA | December 2025

AMA | December 2025

Welcome to the December 2025 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Pa...

15 Joulu 20253h 36min

338 | Ryan Patterson on the Physics of Neutrinos

338 | Ryan Patterson on the Physics of Neutrinos

The story goes that Wolfgang Pauli, who first proposed the existence of neutrinos, was embarrassed to have done so, as it was considered uncouth to hypothesize new particles that could not be detected...

8 Joulu 20251h 26min

337 | Kevin Zollman on Game Theory, Signals, and Meaning

337 | Kevin Zollman on Game Theory, Signals, and Meaning

Game theory is a way of quantitatively describing what happens any time one thing interacts with another thing, when both things have goals and potential rewards. That's a pretty broad class of intere...

1 Joulu 20251h 17min

336 | Anil Ananthaswamy on the Mathematics of Neural Nets and AI

336 | Anil Ananthaswamy on the Mathematics of Neural Nets and AI

Machine learning using neural networks has led to a remarkable leap forward in artificial intelligence, and the technological and social ramifications have been discussed at great length. To understan...

24 Marras 20251h 14min

AMA | November 2025

AMA | November 2025

Welcome to the November 2025 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Pa...

17 Marras 20253h 34min

335 | Andrew Jaffe on Models, Probability, and the Universe

335 | Andrew Jaffe on Models, Probability, and the Universe

Science has an incredibly impressive track record of uncovering nonintuitive ideas about the universe that turn out to be surprisingly accurate. It can be tempting to think of scientific discoveries a...

10 Marras 20251h 17min

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