198 | Nick Lane on Powering Biology

The origin of life here on Earth was an important and fascinating event, but it was also a long time ago and hasn't left many pieces of direct evidence concerning what actually happened. One set of clues we have comes from processes in current living organisms, especially those processes that seem extremely common. The Krebs cycle, the sequence of reactions that functions as a pathway for energy distribution in aerobic organisms, is such an example. I talk with biochemist about the importance of the Krebs cycle to contemporary biology, as well as its possible significance in understanding the origin of life.

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Nick Lane received his PhD from the Royal Free Hospital Medical School. He is currently a professor of Evolutionary Biochemistry at University College London. He was a founding member of the UCL Consortium for Mitochondrial Research, and is Co-Director of the UCL Centre for Life's Origin and Evolution. He was awarded the 2009 UCL Provost's Venture Research Prize, the 2011 BMC Research Award for Genetics, Genomics, Bioinformatics and Evolution, the 2015 Biochemical Society Award, and the 2016 Royal Society Michael Faraday Prize and Lecture. His new book is Transformer: The Deep Chemistry of Life and Death.


Jaksot(416)

334 | Daniel Whiteson on the Physics of and by Aliens

334 | Daniel Whiteson on the Physics of and by Aliens

The universe as revealed by physics is objective: it's out there, existing and behaving in ways that are completely independent of human thought. But the process by which we learn about the universe, ...

3 Marras 20251h 14min

333 | Gordon Pennycook on Unthinkingness, Conspiracies, and What to Do About Them

333 | Gordon Pennycook on Unthinkingness, Conspiracies, and What to Do About Them

Why are people wrong all the time, anyway? Is it because we human beings are too good at being irrational, using our biases and motivated reasoning to convince ourselves of something that isn't quite ...

27 Loka 20251h 10min

332 | Dmitri Tymoczko on the Mathematics Behind Music

332 | Dmitri Tymoczko on the Mathematics Behind Music

Music is math that you can dance to. The fact that certain notes sound good when played together, or in succession, is related to the mathematical properties of the frequencies to which they correspon...

20 Loka 20251h 21min

AMA | October 2025

AMA | October 2025

Welcome to the October 2025 Ask Me Anything episode of Mindscape! These monthly excursions are funded by Patreon supporters (who are also the ones asking the questions). We take questions asked by Pat...

13 Loka 20253h 37min

331 | Solo: Fine-Tuning, God, and the Multiverse

331 | Solo: Fine-Tuning, God, and the Multiverse

Certain features of our universe seem unnatural to us. These include "constants of nature" such as the cosmological constant and the mass of the Higgs boson, as well as features of the initial conditi...

6 Loka 20251h 54min

330 | Petter Törnberg on the Dynamics of (Mis)Information

330 | Petter Törnberg on the Dynamics of (Mis)Information

A characteristic of complex systems is that individual components combine to exhibit large-scale emergent behavior even when the components were not specifically designed for any particular purpose wi...

29 Syys 20251h 12min

329 | Steven Pinker on Rationality and Common Knowledge

329 | Steven Pinker on Rationality and Common Knowledge

Getting along in society requires that we mostly adhere to certainly shared norms and customs. Often it's not enough that we all know what the rules are, but also that everyone else knows the rules, a...

22 Syys 20251h 16min

328 | Mary Roach on Replacing Parts of Our Bodies

328 | Mary Roach on Replacing Parts of Our Bodies

Like any machine, bodies occasionally break down, and it's natural to go in search of a replacement part. Ancient societies featured simple prosthetics for teeth, noses, and limbs, while modern medici...

15 Syys 20251h 7min

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