Ep 339 - ECA Stack & Yohimbine

Ep 339 - ECA Stack & Yohimbine

In this episode of Iron Culture, Helms and Trex have a lengthy discussion about the ECA stack and yohimbine. The history, the mechanisms, the regulatory changes, the practical applications – you name it, they cover it. Don’t miss this episode if you have an interest in fat loss, stimulants, or dietary supplementation in general.


Also, be sure to check out the newest issue of the MASS Research Review! Learn more at massresearchreview.com


Time stamps

0:00 Intro

4:18 New issue of the MASS Research Review

10:42 Helms contest prep update

13:15 The history of the ECA stack and supplement regulation

30:07 Ephedra vs Ephedrine

35:31 Why people took ephedrine / ECA stack

36:30 Trends in PED use over time

45:00 Research on the ECA stack

50:58 Banning lifters for stimulant use

53:15 Effects of ephedrine + caffeine on metabolism and fat loss

1:02:44 What does aspirin really add to the ECA stack?

1:13:00 Do NSAIDs blunt hypertrophy?

1:21:25 How yohimbine works (and yohimbe vs yohimbine distinction)

1:31:10 Regulatory status of yohimbine

1:32:58 Practical applications

Jaksot(133)

Ep 332 - The Most Extreme Metabolic Adaptation Ever Recorded

Ep 332 - The Most Extreme Metabolic Adaptation Ever Recorded

In this episode, the hosts discuss various aspects of bodybuilding prep, including caloric intake, metabolic adaptation, and the impact of extreme dieting. They explore historical studies that provide...

18 Kesä 20251h 13min

Ep 331 - Contest Prep and Weight Cutting Across Sports

Ep 331 - Contest Prep and Weight Cutting Across Sports

In this episode of Iron Culture, the Erics begin by discussing Helms' prep updates and the standout performances from the recent powerlifting World Champions. The conversation also touches on body com...

11 Kesä 20251h 10min

Ep 330 - Female Health & Fitness Research + Q&A

Ep 330 - Female Health & Fitness Research + Q&A

In this episode of the Iron Culture Podcast, the Erics discuss various topics including updates on Helms' contest prep vlog, a preview of the upcoming Powerlifting World Championships, misconceptions ...

4 Kesä 20251h 20min

Ep 329 - What To Do About Microplastics

Ep 329 - What To Do About Microplastics

What's the deal with microplastics? Where do they come from? Are they in our bodies? If so, are they harmful? Also, what's the deal with microwaving Tupperware and other plastic containers?This episod...

30 Touko 20251h 31min

Ep 328 - Bad Fundamentals Lead to Popular Pseudoscience

Ep 328 - Bad Fundamentals Lead to Popular Pseudoscience

In this episode of Iron Culture presented by MASS, Dr. Eric Helms and Dr. Eric Trexler dive into a wide-ranging discussion covering updates on the long-awaited 3rd edition of the Muscle & Strength Pyr...

22 Touko 20251h 34min

Ep 327 - Fat Loading, Sodium Limits, and More

Ep 327 - Fat Loading, Sodium Limits, and More

In this episode of Iron Culture, hosts Eric Trexler and Eric Helms discuss a variety of topics related to bodybuilding, nutrition, and fitness. First they share updates on Front Page Fitness and discu...

14 Touko 20251h 27min

Ep 326 - Daily 1RM Training: Crazy or Constructive? (ft. Dr. Nick Washmuth and Kaylee Chism)

Ep 326 - Daily 1RM Training: Crazy or Constructive? (ft. Dr. Nick Washmuth and Kaylee Chism)

In this episode of Iron Culture, hosts Eric Helms and Michael Zourdos reconnect and reflect on their experiences at the 2025 Sports Nutrition Association annual conference. Joined by guests Dr. Nick W...

7 Touko 20251h 45min

Ep 325 - Plant-Based Bodybuilding With a World Champ (ft. Maddie McConnell)

Ep 325 - Plant-Based Bodybuilding With a World Champ (ft. Maddie McConnell)

In this episode of Iron Culture, Eric Helms and Trexler welcome Maddie McConnell, a world champion natural physique athlete, to discuss the current trends in natural bodybuilding, her journey into the...

30 Huhti 20251h 49min

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