Part 43 - Dr. Dale Bredesen and the End of Alzheimer's, How YOU Can Prevent it, and Hope for All Degenerative Diseases

Part 43 - Dr. Dale Bredesen and the End of Alzheimer's, How YOU Can Prevent it, and Hope for All Degenerative Diseases

This is an interview I've been looking forward to for years. Dr. Dale Bredesen is shaking up the medical world by showing that Alzheimer's actually can be prevented, treated, and sometimes even reversed. This is really important to me because my mom is the final stages of Alzherimer's and I, of course, am doing everything I can to prevent myself from falling to the same fate.

I believe the Sapien way of eating and lifestyle is doing just that - setting me up for my best chances at my longest healthspan. You can learn more about this at http://sapien.org/diet

Dr. Bredesen and I agree on all the core principles. He really is describing a Sapien diet with his protocol. We're only at odds with the ratio of plant foods to animal foods.

As I've posted today on social media, I think people are actually more on the side of animal foods than they think. In the context of a whole foods, low carb diet without refined grains, sugar or vegetable oil, more often than not people are getting the majority of their calories from animal foods without necessarily realizing it. Only people eating Standard American Diets or Mediterranean Diets and the like are getting most of their calories from plant foods from all the empty calories coming from grains and other carbohydrates.

Many health figures in this space say things like "a plant heavy diet" or "fill half your plate up with greens" and people take this as being akin to a vegetarian diet. As I showed in my post, a daily intake where about 70% of the plates are filled with plants are actually 92% animal foods by calories.

I actually eat this way a lot. This is carnivore adjacent and is part of the Sapien Framework. You're still getting a ton of flavor, variety, and nutrients from plants (even though they're not as bioavailable), but you're really getting 90% of your calories from animal foods. So make your own decision on the ratio of plant to animal foods, but from what I've found, higher animal foods is more species appropriate for homo sapiens, and is actually what most people avoiding empty calorie, nutrient poor foods are already doing.

As always, I didn't want to press him on this. I don't invite people on my podcast to tell them I don't agree with their opinions. I'd love for this to be debated with a moderator at some point, but as long as it's a 1 on 1 Peak Human podcast I'm letting the guest speak their minds.

Here's a bit of Dr. Bredesen's extensive resume. He received his undergraduate degree from Caltech and his medical degree from Duke. He served as Resident and Chief Resident in Neurology at UCSF, he was the Director of the Easton Center for Alzheimer's Disease Research, he's a Professor in the Department of Molecular and Medical Pharmacology at UCLA School of Medicine, and the Founder of the Buck Institute for Research on Aging.

The Bredesen Laboratory studies basic mechanisms underlying the neurodegenerative process, and the translation of this knowledge into effective therapeutics for Alzheimer's disease and other neurodegenerative conditions, leading to the publication of over 220 research papers. He and his group developed a new approach to the treatment of Alzheimer's disease, and this approach led to the discovery of subtypes of the disease, followed by the first description of reversal of symptoms in patients with MCI and Alzheimer's disease, with the ReCODE protocol, published in 2014, 2016, and 2018. His book, The End of Alzheimer's, is a New York Times Bestseller and has been translated into 29 languages.

I'll largely skip the plugs for today. Everyone listening knows about the Food Lies film on Indiegogo, the Patreon at http://patreon.com/peakhuman and my new grass fed meat company http://NoseToTail.org If you find any value in this podcast or my other content on YouTube or social media channels, please consider supporting me and my projects there. I wish I could really get across how much it means to me. It's honestly the only way any of this is possible. Thanks so much, and I'll most likely end season 3 with this episode and come back in a couple weeks with an amazing season 4. Here's the future legend, Dr. Dale Bredesen.

BUY THE MEAT NosetoTail.org

Preorder Food Lies: http://indiegogo.com/projects/food-lies-post

Support me on Patreon! http://patreon.com/peakhuman

SHOW NOTES

  • Dr. Bredesen has been studying the phenomenon of Alzheimer's Disease (AD) for 3 decades and have published over 200 papers on his research
  • Understanding the fundamental nature of the disease is how we can design an effective treatment
  • His protocol is different because it targets the root cause, not the symptoms like most AD drugs do
  • Humans are extremely complicated and there is no one single therapy that will treat the complexity of AD
  • AD is the result of the brain protecting itself from different insults
  • The protective response in the brain causes the brain to shrink and "retreat" so that there is less for foreign substances (insults) to target
  • Amyloids are antimicrobial, bind to toxins, and change the brain's response to glucose but when they are overproduced and build up that's when problems occur
  • Some of the contributors to AD are: chronic inflammation, insulin resistance, glycation damage, toxin exposure, decrease in nutrients, hormones, trophic factors, poor vascular support
  • He has identified and categorized 6 different types of AD: inflammatory, atrophic, glycotoxic, toxic, vascular, and traumatic
  • Paraffin candles produce toxins that damage the brain
  • Most damaging mycotoxins (produced from mold) are the ones you breathe - test your home for molds
  • Go to www.survivingmold.com to learn how to test your home for mold and if you are concerned about mold exposure to learn about what to personally get tested
  • For overall markers you should get tested, you can order tests directly from Dr. Bredesen's site www.drbredesen.com or go to your doctor and test markers
  • Markers for glycotoxicity: fasted insulin, HbA1c, and fasted glucose
  • Markers for nutrients, hormones, and trophic factors: o Vit. D, pragnenolone, progesterone, estradiol, testosterone, free T3 and free T4 (for thyroid), TSH (thyroid stimulating hormone), and reverse T3 (which is an inhibitor of the effect of your active thyroid hormone)
  • Inflammation markers: HS-CRP, TNF-a, IL6, IL8, IL1-b
  • Don't wait until it's too late to check for these things, because AD is preventable
  • Glycotoxicity and how sugar is toxic
  • Humans are not designed to eat sugar
  • Overconsumption of sugar is linked to hypertension, CVD, diabetes, dementia, arthritic, leaky gut, and more
  • Sugar is this generation's smoking, we will get to a day when we think back to how crazy it was that we were eating this stuff
  • We have biomarkers that will tell you whether AD is creeping up on you, so check early in life because you might not feel sick now, but that doesn't mean it's not on its way
  • All these lifestyle and diet changes that you make to prevent AD, apply to so many other modern illnesses
  • If AD runs in your family, you should be interested in prevention
  • AD should be a rare disease
  • APOE4 is the most common genetic risk factor
  • If you have a single copy of APOE4 the risk is ~30%
  • If you have a double copy of APOE4 the risk becomes greater than 50%
  • For people with APOE4, find out early and get on prevention, and you will have a low chance of getting the disease
  • 21st century medicine is about root cause and prevention
  • There is no mono-therapy for AD
  • Look out for symptoms of early cognitive decline like the lack of ability to learn new things, losing organizational skills, not being able to do simple calculations, not being able to find the right word, getting lost in familiar places
  • Don't shake these off as "senior moments"
  • Basic things everyone can do: optimize insulin sensitivity, follow a low-carb, moderate protein, high (good) fat diet, exercise, get enough sleep, reduce stressors in your life, detox, avoid or fix any gut issues, go into periods of ketosis
  • His diet plan is called "KetoFlex 12/3"
  • "Keto" for going into periods of ketosis
  • "Flex" because it is flexitarian, if you want to be a vegetarian or eat meat you can do either
  • "12" because he wants people fasting for at least 12 hours between dinner and the next day's first meal
  • "3" because he wants people to finish eating at least 3 hours before they go to sleep
  • The Big Four to avoid: grains, simple carbs, dairy, and lectins
  • He has had amazing success with his patients and has been publishing results since 2014
  • He has never had someone at risk come in for prevention and develop even mild cognitive impairment (MCI)
  • People who come in with subjected cognitive impairment (SCI) see improvement
  • People who come in with MCI the majority improve
  • People with full-blown AD, some people improve and some people don't
  • He has had people score zero on cognitive tests that have improved
  • The most important point of all of this is that if you get put on a drug for AD you might get a little bump but you fall back to declining again, his approach targets what is actually causing the decline, the people who get better sustain their improvement
  • Complexity gap between the complexity of the problem (human illness) and the data sets that traditional medical doctors are using to treat them (aka we can't expect a simple mono-therapy to treat a complex condition)
  • Dr. Bredesen's daughter is a brain health coach and you can find her at www.siabrainhealth.com
  • His protocol includes sauna for riding the body of toxins
  • We are swimming in an Alzheimer's soup with the amount of toxins we are exposed to in our modern world
  • Get rid of toxins by sweating (sauna and exercise), high fiber diet, optimizing glutathione levels, filtered water, urination, each one of these gets rid of different things
  • If you have leaky gut, fix that
  • The importance of sleep
  • Current research on macular degeneration
  • His new book coming out "The First Survivors of Alzheimer's Disease" will be about people's first-hand stories of people told they had no hope but used his protocol and got better and have kept themselves better
  • The future of medicine will need to look at how humans were evolutionarily designed to live
  • You are not powerless to AD, you have control over it
  • We can reduce the global burden of dementia, we can fight cognitive decline
  • Find Dr. Dale Bredesen at www.drbredesen.com
  • His Facebook page https://facebook.com/drdalebredesen/

BUY THE MEAT NosetoTail.org

Support me on Patreon! http://patreon.com/peakhuman

Preorder the film here: http://indiegogo.com/projects/food-lies-post

Film site: http://FoodLies.org

YouTube: https://www.youtube.com/c/FoodLies

Sapien Movement: http://SapienMovement.com

Follow along:

http://twitter.com/FoodLiesOrg

http://instagram.com/food.lies

http://facebook.com/FoodLiesOrg

Theme music by https://kylewardmusic.com/

Jaksot(233)

Part 161 - Dr. Frederic Leroy Unravels 100 years of the Anti-Meat Agenda

Part 161 - Dr. Frederic Leroy Unravels 100 years of the Anti-Meat Agenda

Specializing in the science and application of animal foods in society and nutrition, Dr. Frederic Leroy is a food scientist, technologist and professor at the University of Brussels. With a dense background in peer-reviewed journals, academic boards, and nonprofits, Dr. Leroy currently is an advocate for a deeper, more nuanced discussion of the importance of animal products, an understanding our our historic relationships with them, and the current war against them in western cultures. Frederic's Twitter Page Watch on YouTube: https://youtu.be/lKGeRAB-K3E Dr. Leroy's slides: https://drive.google.com/file/d/1z7l1vmwCWPnHbyS4BVP-1dx6Jo46dP_a/view?usp=sharing GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org SHOW NOTES [4:10] - Brian and Frederic discuss how the overall health of a society relates to diet and nutrition and how modern fake food plays into them [12:15] - How fake meat corporations are trying to make animal agriculture industry disappear [15:30] - Our connection to butchering, modern animal butchering and how they play into our separation to our ancient ways of living [26:50] - Diving into sensationalism in DailyMail articles since 2000 around Meat [32:50]- Why nuance and context always matters when speaking about foods and specifically meat [35:50] - Do we need meat? Is it fundamental to health? [47:20] - How meat, animal foods, and our relationships to animals provided security for hunter-gatherer communities interactions with animals is changing: slaughtering, butchering, consumption [1:108:30] - The hierarchy of our modern society and the agendas to form mobs, embrace authority, and subvert power [1:22:00] - How our view of death has changed and its role in our our view of meat/animal products [1:29:00] - How to have a societal and individual relationships with animals that are healthy for you, the community and the earth GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

1 Kesä 20221h 47min

Part 160 - Kara Collier on Optimal Health Through Blood Sugar Regulation

Part 160 - Kara Collier on Optimal Health Through Blood Sugar Regulation

Kara Collier is a Registered Dietician Nutritionist and a co-founder of Nutri-Sense, currently leading their team of dieticians to using their continuous glucose monitoring systems to help individuals properly manage their glucose and metabolism. She graduated from Purdue University, previously worked at the Memphis VA medical center as a clinical dietician at Providence Hospital and in a management role at Nutritionix   Use code "PeakHuman" at Nutrisense for $25 off a CGM     GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org   SHOW NOTES [0:30] - Kara details her past and what motivated her to get involved with healthcare, metabolic health and Nutrisense and [5:00] - How using a continuous glucose monitor can increase your awareness of how foods affect your glucose levels, energy, mood etc. [14:30] - How your body adapts to lower levels of carbohydrates in diet and its effects [16:30] - Detailing glucose and its role in metabolism [20:30] - What is a Continuous Glucose Monitor, what it tells you and who might benefit from using it [25:05] - Why Hemoglobin A1c is not the only indicator of your metabolic health and what can make those results less reliable [34:15] - Why its very hard and uncommon for the traditional healthcare system to prescribe beneficial testing as preventative care [41:10] - Lipids, LDL, HDL, Trigs and how their levels affect overall health [48:15] - Lifestyle factors and basic nutrition guidelines to maximize glucose response and metabolic health [58:00] - How Sleep and Alcohol affect glucose response and health [1:11:00] - How larger meals, like an OMAD format, affects your glucose response and metabolism [1:16:00] - Do we know if eating a bunch of fruit and sugar is good/bad?   BUY THE MEAT NosetoTail.org Support me on Patreon! http://patreon.com/peakhuman Preorder the film here: http://indiegogo.com/projects/food-lies-post   Film site: http://FoodLies.org YouTube: https://www.youtube.com/c/FoodLies   Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

25 Touko 20221h 24min

Part 159 - Patrick Theut on the Miraculous Reversal of Heart Disease

Part 159 - Patrick Theut on the Miraculous Reversal of Heart Disease

Patrick Theut is a biochemist and engineer who has successfully managed to reverse his coronary artery disease. He has invested over 16,000 hours of study into the cause of heart disease. He has developed theories and protocols on how this disease is developed, how to stop it from progressing, and protocols to even reverse it. Vitamin K Website The ancestral health & events center in East Austin is getting closer to becoming a reality! Email Brian at hi@foodlies.org to get involved. We're looking for anyone from members to investors! GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org SHOW NOTES [3:50] - Patrick details his life-changing scare with a high Coronary Artery Calcium score [14:04] - Why he thinks a MMR jab negatively affected his life [24:30] - Patrick's mission to get high quality vitamin K to solve his heart disease [29:45] - Why Patrick thinks that conventional western medicine doesn't routinely test for CAC and other root cause issues [40:00] - A breakdown of Fats, Lipids, hormonal health, and the importance of LDL [57:50] - Brian and Patrick Discuss healthy diet and lifestyle factors [1:20:00] - What to do once your get a CAC score [1:27:45] - The "hydra" of heart disease GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

18 Touko 20221h 40min

Part 158 - Dr. Tyna Moore on The Secrets to Living a Long & Pain-Free Life

Part 158 - Dr. Tyna Moore on The Secrets to Living a Long & Pain-Free Life

11 Touko 20221h 8min

Part 157 - Jessica Thompson, PhD on How Eating Animal Fat & Marrow Made Us Human

Part 157 - Jessica Thompson, PhD on How Eating Animal Fat & Marrow Made Us Human

Specializing in human evolution and the aspects revealed through the analysis of ancient animal bones, Jessica Thomspon is a leading voice in paleo-anthropology, evolutionary theory and hunter-gatherer ethnography. She is a professor at Yale University and also leads the Malawi ancient Lifeways and Peoples Project in Malawi, in central Africa, to develop and interpret the evolutionary history in the area during the last Ice Age. Jessica thompson PhD website: https://campuspress.yale.edu/jcthompson/ The ancestral health & events center in East Austin is getting closer to becoming a reality! Email Brian at hi@foodlies.org to get involved. We're looking for anyone from members to investors! GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org SHOW NOTES: [0:30] - Dr. Jessica speaks about getting back on campus at Yale University and her specialties research in the field of anthropology [5:40] - Jessica's take on where and when we started as a human species [10:10] - What is the difference in diet, structure, etc. between humans and primates split around 7+ million years ago? [16:40] - Diving deep into tool marks on bones and what we can learn from them [24:40] - Jessica shares her opinion on the nuance of why our evolutionary adaptations that make us human occurred [36:10] - Did protein or fat change human evolution? [55:22] - The importance that megafauna played in our evolution and how they played into cooperation and competition in populations [57:05] - Jessica shares her thoughts on adaptations to the type of energy we consume such as milk, fat, etc. as it relates to the genes/skills that get passed down [1:01:00] - The massive shift in our modern diet in the short time frame, causing massive implications in long-term health [1:09:19] - Jessica weighs in on the role of animal products on evolution and our current health [1:17:30] - Jessica's thoughts on longevity and biological anthropology GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

27 Huhti 20221h 37min

Part 156 - Keith Norris on Becoming Healthy & Free in Our Crazy Modern World

Part 156 - Keith Norris on Becoming Healthy & Free in Our Crazy Modern World

Keith Norris is an author, speaker, and the founder of Paleo f(x), the world's premier holistic wellness event, covering health, nutrition, spirituality, entrepreneurship and everything in between, which is happening on the 29th of April  through May 1st.    BUY ONE, GET ONE FREE TICKETS   He and his wife also recently wrote a book, Primal Uprising, The Paleo f(x) Guide to Optimizing Your Health, Expanding Your Mind, and Reclaiming Your Freedom Keith and Michelle's book Primal Uprising  Paleo f(x) tickets and teaser video   GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org   SHOW NOTES: [0:00] - Brian and Keith catch up and chat about when they first met and Paleo f(x) [10:02] - Keith speaks his mind on living in "bubbles" and the different types that exist in areas, the ideologies that go along with it and Brian's own bubbles [14:40] - Neuro Linguistic Programming - what it is and how to use it for more success [23:15] - Willpower, Nutrient Density, Anthropology and Vegetarianism  [47:30] - Redpilling, Food Guidelines, and Effective thinking  [1:01:00] - Censorship and confronting the establishment by beginning with yourself     GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org   Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

20 Huhti 20221h 19min

Part 155 - Dr. Malcolm Kendrick on The True Cause of Heart Disease? The Unifying Theory

Part 155 - Dr. Malcolm Kendrick on The True Cause of Heart Disease? The Unifying Theory

Dr. Malcolm Kendrick is a General Practitioner in Medicine from Scotland, and focuses the bulk of his research and writing on cholesterol, atherosclerosis, stress, and the myths around them. He is an outspoken critic of the cholesterol focus of heart disease, overprescription of medications, and the dirty plays of statistics that some doctors use to increase their gains at the expense of their patients and general population. He is the author of three books, The Clot Thickens, Doctoring Data, and The Cholesterol Con, and runs the website drmalcolmkendrick.org GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org SHOW NOTES: [0:50] - Brian and Malcolm chat about Malcolm recent book, The Clot Thickens, and a brief overview of heart disease, its history and Malcolm's thoughts on it [10:01] - Malcolm details the nuance of atherosclerosis, endothelial cells, and damage to blood vessels [19:40] - Malcolm's thoughts on using LDL as a risk factor for cardiovascular events [31:20] - Myths and facts around cholesterol and its role in physiology [36:00] - Diving deep into Malcolm's thrombogenic hypothesis of heart disease, blood clots and endothelial pathology, Sickle Cell disease and Diabetes [59:21] - Nitric oxide, how it's benefits were found and how to increase it [1:04:21] - How stress correlates to increased risk of cardiovascular disease [1:08:45] - Malcolm's thoughts on lifestyle, diet, and relationships that help or hurt your chances of adverse cardiovascular events [1:14:30] - How Malcolm's thoughts on these topics have changed or cumulated over the years GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

13 Huhti 20221h 23min

Part 154 - Zoe Harcombe PhD on the Upside Down World of Health Policy

Part 154 - Zoe Harcombe PhD on the Upside Down World of Health Policy

Zoe Harcombe, PhD is a researcher, author, blogger and public speaker in the field of diet and health. Her areas of interest/expertise are public health dietary guidelines (especially dietary fat), nutrition and obesity. She regularly is interviewed on TV, radio, newspapers and magazines.   She has a BA and MA from Cambridge University (economics/maths) as well as a Ph.D. in public health nutrition. Her thesis title was "An examination of the randomised controlled trial and epidemiological evidence for the introduction of dietary fat recommendations in 1977 and 1983: A systematic review and meta-analysis." The full document is available to site members here.   Zoe has also offered 50% a year membership to her amazing website where you get all of her articles. My listeners can use this code PH2204 https://www.zoeharcombe.com/register/membership-annual   GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org   SHOW NOTES [1:30] - Zoe's background and why she wrote her thesis on the lack of evidence for the introduction of food guidelines [4:30] - Cutting calories and why it doesn't work to focus on it  [10:40] - Brian asks Zoe how to properly lose fat [16:30] - Zoe's take on low carb and what she thinks we should be eating  [27:40] - Zoe's take on animal vs plant foods in relation to nutrition and protein content [39:30] - Zoe's take on the Food Pyramid and how we got into this awful situation  [50:05] - Power dynamics in society and how it relates to our approach towards kids' health in western societies [1:07:40] - Zoe's thoughts on the World Health Organization and The Great Reset [1:20:50] - How this conversation ties into the ostracisation on red meat and the organizations behind it   GET THE MEAT http://NosetoTail.org FREE SAPIEN FOOD GUIDE http://sapien.org   Follow along: http://twitter.com/FoodLiesOrg http://instagram.com/food.lies http://facebook.com/FoodLiesOrg

7 Huhti 20221h 30min

Suosittua kategoriassa Terveys ja hyvinvointi

unicast
tiedenaiset-podcast
rss-pitaisko-erota
voi-hyvin-meditaatiot-2
meditaatiot-suomeksi
psykopodiaa-podcast
vakeva-elama-viisaampi-mieli-vahvempi-keho
terapiassa
junnut-pelissa
paritellen
rss-kuumilla-aalloilla
selvin-pain
fitnessvastaanotto
rss-en-saa-unta
selviytyjat-tarinoita-elamasta
rss-mighty-finland-podcast
rss-nautinto
rss-narsisti
kaikki-ihonhoidosta
rss-rentoudu-podcast-rentoutumiseen-hanna-viljanmaa