
Pathophysiology of Obesity, Part 10 — Yo-Yo Dieting and Weight Cycling
Meet Sarah. Over the last decade, she's tried everything: keto, intermittent fasting, juice cleanses, low-fat diets. Every time, the pattern is the same. She loses 20 pounds, and within months the wei...
14 Huhti 4min

Pathophysiology of Obesity, Part 9 — The Set Point Theory
If you've ever lost weight on a diet only to see it creep back within months, you're not alone. Your experience reflects one of the most important theories in obesity science: the set point theory. Ou...
9 Huhti 4min

Pathophysiology of Obesity, Part 8 — Why Your Body Defends Fat Mass
Why is losing weight so hard and keeping it off nearly impossible? The answer lies in how our brain and gut are wired to protect fat mass, just like they protect red blood cells, bone, or muscle mass....
7 Huhti 4min

Pathophysiology of Obesity, Part 7 — Energy Balance and the Gut-Brain Connection
Energy balance sounds simple: calories in versus calories out. But it's actually a delicate conversation between the gut and the brain, orchestrated by the hypothalamus. Your brain and gut are in cons...
2 Huhti 5min

Pathophysiology of Obesity, Part 6 - The Gut-Brain Conversation
Our gut constantly talks to our brain through a symphony of hormones that control hunger, fullness, and energy balance. Some hormones rev up appetite, while others apply the brakes.In this episode, we...
31 Maalis 4min

Pathophysiology of Obesity, Part 5 - Insulin: The Gatekeeper
When people say "I'm doing everything right, but the weight won't come off," the answer often lies in insulin resistance.Insulin is the key that unlocks your cells so glucose can enter. Once inside, y...
26 Maalis 6min

Pathophysiology of Obesity, Part 4 — Leptin: The Broken Thermostat
In 1994, scientists discovered leptin, a hormone made by fat cells that tells your brain you've had enough to eat. They thought it was the cure for obesity.But here's the twist: most people with obesi...
24 Maalis 5min

Pathophysiology of Obesity, Part 3 — The Hormonal Storm
Obesity isn't just about food and calories. It's about a highly complex network of hormones that tells you when to eat, when to stop, and how much energy to burn. When that system gets disrupted, ever...
19 Maalis 5min



















