2025 Highlight-o-thon: Oops! All Bests

2025 Highlight-o-thon: Oops! All Bests

It’s that magical time of year once again — highlightapalooza! Stick around for one top bit from each episode we recorded this year, including:

  • Kyle Fish explaining how Anthropic’s AI Claude descends into spiritual woo when left to talk to itself
  • Ian Dunt on why the unelected House of Lords is by far the best part of the British government
  • Sam Bowman’s strategy to get NIMBYs to love it when things get built next to their houses
  • Buck Shlegeris on how to get an AI model that wants to seize control to accidentally help you foil its plans

…as well as 18 other top observations and arguments from the past year of the show.

Links to learn more, video, and full transcript: https://80k.info/best25

It's been another year of living through history, whether we asked for it or not. Luisa and Rob will be back in 2026 to help you make sense of whatever comes next — as Earth continues its indifferent journey through the cosmos, now accompanied by AI systems that can summarise our meetings and generate adequate birthday messages for colleagues we barely know.

Chapters:

  • Cold open (00:00:00)
  • Rob's intro (00:02:35)
  • Helen Toner on whether we're racing China to build AGI (00:03:43)
  • Hugh White on what he'd say to Americans (00:06:09)
  • Buck Shlegeris on convincing AI models they've already escaped (00:12:09)
  • Paul Scharre on a personal experience in Afghanistan that influenced his views on autonomous weapons (00:15:10)
  • Ian Dunt on how unelected septuagenarians are the heroes of UK governance (00:19:06)
  • Beth Barnes on AI companies being locally reasonable, but globally reckless (00:24:27)
  • Tyler Whitmer on one thing the California and Delaware attorneys general forced on the OpenAI for-profit as part of their restructure (00:28:02)
  • Toby Ord on whether rich people will get access to AGI first (00:30:13)
  • Andrew Snyder-Beattie on how the worst biorisks are defence dominant (00:34:24)
  • Eileen Yam on the most eye-watering gaps in opinions about AI between experts and the US public (00:39:41)
  • Will MacAskill on what a century of history crammed into a decade might feel like (00:44:07)
  • Kyle Fish on what happens when two instances of Claude are left to interact with each other (00:49:08)
  • Sam Bowman on where the Not In My Back Yard movement actually has a point (00:56:29)
  • Neel Nanda on how mechanistic interpretability is trying to be the biology of AI (01:03:12)
  • Tom Davidson on the potential to install secret AI loyalties at a very early stage (01:07:19)
  • Luisa and Rob discussing how medicine doesn't take the health burden of pregnancy seriously enough (01:10:53)
  • Marius Hobbhahn on why scheming is a very natural path for AI models — and people (01:16:23)
  • Holden Karnofsky on lessons for AI regulation drawn from successful farm animal welfare advocacy (01:21:29)
  • Allan Dafoe on how AGI is an inescapable idea but one we have to define well (01:26:19)
  • Ryan Greenblatt on the most likely ways for AI to take over (01:29:35)
  • Updates Daniel Kokotajlo has made to his forecasts since writing and publishing the AI 2027 scenario (01:32:47)
  • Dean Ball on why regulation invites path dependency, and that's a major problem (01:37:21)


Video and audio editing: Dominic Armstrong, Milo McGuire, Luke Monsour, and Simon Monsour
Music: CORBIT
Coordination, transcripts, and web: Katy Moore

Episoder(331)

#229 – Marius Hobbhahn on the race to solve AI scheming before models go superhuman

#229 – Marius Hobbhahn on the race to solve AI scheming before models go superhuman

We often worry about AI models “hallucinating” or making honest mistakes. But what happens when a model knows the truth, but decides to deceive you anyway to achieve a goal of its own? This isn’t sci-...

3 Des 20253h 3min

Rob & Luisa chat kids, the 2016 fertility crash, and how the 50s invented parenting that makes us miserable

Rob & Luisa chat kids, the 2016 fertility crash, and how the 50s invented parenting that makes us miserable

Global fertility rates aren’t just falling: the rate of decline is accelerating. From 2006 to 2016, fertility dropped gradually, but since 2016 the rate of decline has increased 4.5-fold. In many weal...

25 Nov 20251h 59min

#228 – Eileen Yam on how we're completely out of touch with what the public thinks about AI

#228 – Eileen Yam on how we're completely out of touch with what the public thinks about AI

If you work in AI, you probably think it’s going to boost productivity, create wealth, advance science, and improve your life. If you’re a member of the American public, you probably strongly disagree...

20 Nov 20251h 43min

OpenAI: The nonprofit refuses to be killed (with Tyler Whitmer)

OpenAI: The nonprofit refuses to be killed (with Tyler Whitmer)

Last December, the OpenAI business put forward a plan to completely sideline its nonprofit board. But two state attorneys general have now blocked that effort and kept that board very much alive and k...

11 Nov 20251h 56min

#227 – Helen Toner on the geopolitics of AGI in China and the Middle East

#227 – Helen Toner on the geopolitics of AGI in China and the Middle East

With the US racing to develop AGI and superintelligence ahead of China, you might expect the two countries to be negotiating how they’ll deploy AI, including in the military, without coming to blows. ...

5 Nov 20252h 20min

#226 – Holden Karnofsky on unexploited opportunities to make AI safer — and all his AGI takes

#226 – Holden Karnofsky on unexploited opportunities to make AI safer — and all his AGI takes

For years, working on AI safety usually meant theorising about the ‘alignment problem’ or trying to convince other people to give a damn. If you could find any way to help, the work was frustrating an...

30 Okt 20254h 30min

#225 – Daniel Kokotajlo on what a hyperspeed robot economy might look like

#225 – Daniel Kokotajlo on what a hyperspeed robot economy might look like

When Daniel Kokotajlo talks to security experts at major AI labs, they tell him something chilling: “Of course we’re probably penetrated by the CCP already, and if they really wanted something, they c...

27 Okt 20252h 12min

#224 – There's a cheap and low-tech way to save humanity from any engineered disease | Andrew Snyder-Beattie

#224 – There's a cheap and low-tech way to save humanity from any engineered disease | Andrew Snyder-Beattie

Conventional wisdom is that safeguarding humanity from the worst biological risks — microbes optimised to kill as many as possible — is difficult bordering on impossible, making bioweapons humanity’s ...

2 Okt 20252h 31min

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