EPISODE 30: Timelines of Ageing – What Worms Teach Us About Growing Old
In this episode, we dive into a new version of WormGazer as described in a recent GeroScience paper. This implementation automates movement monitoring in C. elegans populations as a rapid healthspan m...
8 Okt 202512min
EPISODE 29: Hidden Circuits – Mapping How Worms Really Think
Is a wiring diagram enough to understand the brain? In this episode, we dive into how researchers combined whole-brain optogenetic stimulation with calcium imaging in C. elegans to reveal functional n...
24 Sep 202512min
EPISODE 28: Colour Coded – How Blind Worms See Danger in Blue
Worms without eyes shouldn’t see colour — yet C. elegans can. In this episode, we dive into a landmark study that shows how worms use blue-to-amber light ratios to make foraging decisions. When expose...
10 Sep 202513min
EPISODE 27: Scent of Supper – How Worms Sniff Out Nutritious Bacteria
How does a worm know what’s good for dinner? In this episode, we uncover how C. elegans can distinguish between helpful and harmful microbes — and it’s all down to polyamines. These microbe-produced m...
3 Sep 202513min
EPISODE 26: Eat, Inhibit, Lay – How Worms Tune Reproduction to Food
Why do C. elegans lay eggs only when food is around? In this episode, we explore a newly uncovered neuromodulatory circuit that links food detection to reproductive behaviour using a clever form of di...
27 Aug 202518min
EPISODE 25: Heavy Worms, Light Data – Proteomics Gets Personal in C. elegans
In this episode, we dive into a milestone in C. elegans systems biology — the first application of SILAC-style metabolic proteome labelling in a whole animal. By feeding worms lysine auxotroph E. coli...
20 Aug 202519min
EPISODE 24: Worms on the Chip – Machine Learning Meets Toxicology
In this episode, we explore a high-tech twist on developmental toxicology. Researchers have combined microfluidic engineering with machine learning to automate the analysis of thousands of C. elegans ...
13 Aug 202519min
EPISODE 23: Magnetic Minds – Worms Reveal Brain-Wide Signals in Real Time
In this episode, we follow Caenorhabditis elegans into the magnetic field. Researchers have developed an elegant way to measure whole-brain neural activity in freely moving worms using a calcium-sensi...
6 Aug 202517min
